Proline analogues
L-Proline has a unique role in protein structure in particular in the formation of B-turns. It has both a secondary nucleophilic amine and a carboxylic acid group, which can act as a Brønsted acid. Thus close analogues are of particular interest. The EnamineStore offers many proline analogues, some with additional conformational constraints like fused, spiro or aza-bicyclo systems. Furthermore there are examples of oxa-systems like the 2-oxa-7-azaspiro[4.4]nonane. To see selected examples, browse compounds below:
| Structure | Product info | Availability | Quantity / Price |
|---|---|---|---|
Catalog IDEN300-74879 Product class
Building Block
Nameazetidine-3-carboxylic acid ACD numberMFCD00191763 CAS number36476-78-5 Formula MW101.1 CLogP-2.664 Storage conditionsRT Transport conditionsNormal | Global stock:> 10 g(5 business days) EU Rush delivery(1 g)(2 business days) 1x0.25, 1x0.5, 1x1 |  | |
Catalog IDEN300-1709414 Product class
Building Block
Name4-METHYLAZETIDINE-2-CARBOXYLIC ACID ACD numberMFCD24498411 CAS number1779725-63-1 Formula MW115.1 CLogP-2.453 Storage conditions+4 Transport conditionsNormal | Global stock:> 10 g(5 business days) USA Rush delivery(2 business days) available in New Jersey stock: 1 g 1x0.25, 1x0.5, 1x1 | | |
Catalog IDEN300-6479762 Product class
Building Block
Namerac-(2R,4S)-4-methylazetidine-2-carboxylic acid, trans ACD numberMFCD31700188 CAS number2237226-49-0 Formula MW115.1 CLogP-2.453 Storage conditions+4 Transport conditionsNormal | Global stock:> 10 g(5 business days) USA Rush delivery(2 business days) available in New Jersey stock: 1 g 1x0.002, 1x0.005, 1x0.01, 1x0.02, 1x0.025, 1x0.05, 1x0.1, 1x0.25, 1x0.5, 1x1 | | |
Catalog IDEN300-68611 Product class
Building Block
Name3-methylpyrrolidine-3-carboxylic acid ACD numberMFCD05663313 CAS number885953-27-5 Formula MW129.2 CLogP-2.239 Storage conditionsRT Transport conditionsNormal | Global stock:> 10 g(5 business days) USA Rush delivery(2 business days) available in Ohio stock: 1 g 1x0.25, 1x0.5, 1x1 | | |
Catalog IDEN300-174676 Product class
Building Block
Name(2S)-2-methylpyrrolidine-2-carboxylic acid ACD numberMFCD01318647 CAS number42856-71-3 Formula MW129.2 CLogP0.499 Storage conditionsRT Transport conditionsNormal | Global stock:> 10 g(5 business days) USA Rush delivery(2 business days) available in New Jersey stock: 5 g 1x0.25, 1x0.5, 1x1, 1x2.5, 1x5 | | |
Catalog IDEN300-6477839 Product class
Building Block
Namerac-(2R,3S)-3-fluoropyrrolidine-2-carboxylic acid, trans ACD numberMFCD32066778 CAS number2199280-76-5 Formula MW133.1 CLogP-2.62 Storage conditionsRT Transport conditionsNormal | Global stock:2.4 g(5 business days) EU Rush delivery(0.101 g)(2 business days) 1x0.002, 1x0.005, 1x0.01, 1x0.02, 1x0.025, 1x0.05, 1x0.1USA Rush delivery(2 business days) available in Ohio stock: 0.25 g 1x0.002, 1x0.005, 1x0.01, 1x0.02, 1x0.025, 1x0.05, 1x0.1, 1x0.25 | | |
Catalog IDEN300-373686 Product class
Building Block
Namerac-(2R,4S,6R)-4,6-dimethylpiperidine-2-carboxylic acid ACD number CAS number2089245-52-1 Formula MW157.2 CLogP-0.816 Storage conditionsRT Transport conditionsNormal | Global stock:2.7 g(5 business days) USA Rush delivery(2 business days) available in New Jersey stock: 1 g 1x0.25, 1x0.5, 1x1 | | |
Catalog IDEN300-1477614 Product class
Building Block
Name6-ETHYLPIPERIDINE-2-CARBOXYLIC ACID ACD numberMFCD26045085 CAS number1037471-93-4 Formula MW157.2 CLogP-0.806 Storage conditionsRT Transport conditionsNormal | Global stock:> 10 g(5 business days) USA Rush delivery(2 business days) available in New Jersey stock: 1 g 1x0.25, 1x0.5, 1x1 | | |
Catalog IDEN300-35220 Product class
Building Block
Name2-azabicyclo[2.1.1]hexane-1-carboxylic acid hydrochloride ACD number CAS number116129-07-8 Formula MW163.6 CLogP-0.265 Storage conditionsRT Transport conditionsNormal | Global stock:> 10 g(5 business days) | | |
Catalog IDEN300-88835 Product class
Building Block
Name3-azabicyclo[3.1.0]hexane-1-carboxylic acid hydrochloride ACD numberMFCD11858206 CAS number1181458-33-2 Formula MW163.6 CLogP-2.577 Storage conditionsRT Transport conditionsNormal | Global stock:0.3 g(5 business days) | | |
Catalog IDEN300-88447 Product class
Building Block
Namerac-(1R,5S,6R)-3-azabicyclo[3.1.0]hexane-6-carboxylic acid hydrochloride ACD numberMFCD11099877 CAS number1212105-25-3 Formula MW163.6 CLogP-2.574 Storage conditionsRT Transport conditionsNormal | Global stock:> 10 g(5 business days) | | |
Catalog IDEN300-114208 Product class
Building Block
Name2-(pyrrolidin-2-yl)acetic acid hydrochloride ACD numberMFCD11506301 CAS number71985-79-0 Formula MW165.6 CLogP-2.139 Storage conditionsRT Transport conditionsNormal | Global stock:> 10 g(5 business days) USA Rush delivery(2 business days) available in Ohio stock: 1 g 1x0.25, 1x0.5, 1x1 | | |
Catalog IDEN300-331563 Product class
Building Block
Name3,3-dimethylazetidine-2-carboxylic acid hydrochloride ACD numberMFCD30497784 CAS number2059936-62-6 Formula MW165.6 CLogP-1.934 Storage conditionsRT Transport conditionsNormal | Global stock:> 10 g(5 business days) | | |
Catalog IDEN300-114790 Product class
Building Block
Name2-methylpyrrolidine-2-carboxylic acid hydrochloride ACD numberMFCD22565928 CAS number1423025-85-7 Formula MW165.6 CLogP0.499 Storage conditionsRT Transport conditionsNormal | Global stock:> 10 g(5 business days) | | |
Catalog IDEN300-139285 Product class
Building Block
Name3-methylpyrrolidine-2-carboxylic acid hydrochloride, Mixture of diastereomers ACD numberMFCD26936039 CAS number14704-69-9 Formula MW165.6 CLogP-1.894 Storage conditionsRT Transport conditionsNormal | Global stock:> 10 g(5 business days) USA Rush delivery(2 business days) available in Ohio stock: 5 g 1x0.25, 1x0.5, 1x1, 1x2.5, 1x5EU Rush delivery(1 g)(2 business days) 1x0.25, 1x0.5, 1x1 | | |
Catalog IDEN300-105554 Product class
Building Block
Name3-methylpyrrolidine-3-carboxylic acid hydrochloride ACD numberMFCD22369922 CAS number1222503-25-4 Formula MW165.6 CLogP-2.239 Storage conditionsRT Transport conditionsNormal | Global stock:3.5 g(5 business days) | | |
Catalog IDEN300-301433 Product class
Building Block
Name4-methyl-2-azabicyclo[2.1.1]hexane-1-carboxylic acid hydrochloride ACD numberMFCD30181140 CAS number1955540-92-7 Formula MW177.6 CLogP0.254 Storage conditionsRT Transport conditionsNormal | Global stock:> 10 g(5 business days) | | |
Catalog IDEN300-705715 Product class
Building Block
Namerac-(1R,6S)-2-azabicyclo[4.1.0]heptane-1-carboxylic acid hydrochloride, cis ACD numberMFCD31542473 CAS number2137717-74-7 Formula MW177.6 CLogP0.294 Storage conditionsRT Transport conditionsNormal | Global stock:> 10 g(5 business days) | | |
Catalog IDEN300-6735921 Product class
Building Block
Namerac-(1R,2S,5S)-3-azabicyclo[3.2.0]heptane-2-carboxylic acid hydrochloride ACD number CAS number Formula MW177.6 CLogP-2.099 Storage conditionsRT Transport conditionsNormal | Global stock:> 10 g(5 business days) USA Rush delivery(2 business days) available in Ohio stock: 1 g 1x0.25, 1x0.5, 1x1 | | |
Catalog IDEN300-39280 Product class
Building Block
Name7-azabicyclo[2.2.1]heptane-1-carboxylic acid hydrochloride ACD number CAS number182137-43-5 Formula MW177.6 CLogP0.294 Storage conditionsRT Transport conditionsNormal | Global stock:> 10 g(5 business days) EU Rush delivery(1 g)(2 business days) 1x0.002, 1x0.005, 1x0.01, 1x0.02, 1x0.025, 1x0.05, 1x0.1, 1x0.25, 1x0.5, 1x1 | | |
Catalog IDEN300-73242 Product class
Building Block
Name2-azaspiro[3.3]heptane-6-carboxylic acid hydrochloride ACD numberMFCD11858156 CAS number1172252-57-1 Formula MW177.6 CLogP-3.097 Storage conditions+4 Transport conditionsNormal | Global stock:> 10 g(5 business days) | | |
Catalog IDEN300-204155 Product class
Building Block
Name2-{2-azabicyclo[2.1.1]hexan-1-yl}acetic acid hydrochloride ACD numberMFCD28348295 CAS number637740-18-2 Formula MW177.6 CLogP-2.384 Storage conditions+4 Transport conditionsNormal | Global stock:1.7 g(5 business days) USA Rush delivery(2 business days) available in New Jersey stock: 0.25 g 1x0.25 | | |
Catalog IDEN300-6740513 Product class
Building Block
Name(6S)-5-azaspiro[2.4]heptane-6-carboxylic acid hydrochloride ACD numberMFCD29918531 CAS number2200278-74-4 Formula MW177.6 CLogP-2.099 Storage conditions+4 Transport conditionsNormal | Global stock:> 10 g(5 business days) USA Rush delivery(2 business days) available in New Jersey stock: 1 g 1x0.25, 1x0.5, 1x1 | | |
Catalog IDEN300-295593 Product class
Building Block
Name2-azabicyclo[2.2.1]heptane-1-carboxylic acid hydrochloride ACD numberMFCD30180465 CAS number1955494-71-9 Formula MW177.6 CLogP0.294 Storage conditionsRT Transport conditionsNormal | Global stock:> 10 g(5 business days) USA Rush delivery(2 business days) available in New Jersey stock: 1 g 1x0.25, 1x0.5, 1x1 | | |
Catalog IDEN300-367074 Product class
Building Block
Name(S)-METHYL 4-METHYLENEPYRROLIDINE-2-CARBOXYLATE HCL ACD numberMFCD24856407 CAS number84348-41-4 Formula MW177.6 CLogP0.5 Storage conditions+4 Transport conditionsNormal | Global stock:6.9 g(5 business days) USA Rush delivery(2 business days) available in New Jersey stock: 5 g 1x0.002, 1x0.005, 1x0.01, 1x0.02, 1x0.025, 1x0.05, 1x0.1, 1x0.25, 1x0.5, 1x1, 1x2.5, 1x5 | | |
Catalog IDEN300-1704559 Product class
Building Block
Namerac-(1R,5R)-2-azabicyclo[3.2.0]heptane-1-carboxylic acid hydrochloride, cis ACD numberMFCD31629904 CAS number2173998-87-1 Formula MW177.6 CLogP0.294 Storage conditionsRT Transport conditionsNormal | Global stock:8.0 g(5 business days) USA Rush delivery(2 business days) available in Ohio stock: 1 g 1x0.002, 1x0.005, 1x0.01, 1x0.02, 1x0.025, 1x0.05, 1x0.1, 1x0.25, 1x0.5, 1x1 | | |
Catalog IDEN300-1086669 Product class
Building Block
Namemethyl (2R)-2-methylpyrrolidine-2-carboxylate hydrochloride ACD numberMFCD20685906 CAS number1286768-32-8 Formula MW179.6 CLogP0.784 Storage conditions+4 Transport conditionsNormal | Global stock:> 10 g(5 business days) USA Rush delivery(2 business days) available in New Jersey stock: 1 g 1x0.25, 1x0.5, 1x1 | | |
Catalog IDEN300-1212484 Product class
Building Block
Name3-ethylpyrrolidine-2-carboxylic acid hydrochloride, Mixture of diastereomers ACD numberMFCD20640491 CAS number104757-47-3 Formula MW179.6 CLogP-1.365 Storage conditionsRT Transport conditionsNormal | Global stock:> 10 g(5 business days) USA Rush delivery(2 business days) available in Ohio stock: 1 g 1x0.002, 1x0.005, 1x0.01, 1x0.02, 1x0.025, 1x0.05, 1x0.1, 1x0.25, 1x0.5, 1x1 | | |
Catalog IDEN300-252788 Product class
Building Block
Name3,3-dimethylpyrrolidine-2-carboxylic acid hydrochloride ACD numberMFCD19382435 CAS number61406-78-8 Formula MW179.6 CLogP-1.375 Storage conditionsRT Transport conditionsNormal | Global stock:> 10 g(5 business days) | | |
Catalog IDEN300-1605416 Product class
Building Block
Name4,4-dimethylpyrrolidine-2-carboxylic acid hydrochloride ACD numberMFCD31665535 CAS number2197372-53-3 Formula MW179.6 CLogP-1.375 Storage conditionsRT Transport conditionsNormal | Global stock:> 10 g(5 business days) USA Rush delivery(2 business days) available in Ohio stock: 1 g 1x0.25, 1x0.5, 1x1 | | |
Catalog IDEN300-6478515 Product class
Building Block
Name(3S,6R)-6-methylmorpholine-3-carboxylic acid hydrochloride ACD numberMFCD31695967 CAS number2237216-22-5 Formula MW181.6 CLogP-1.032 Storage conditionsRT Transport conditionsNormal | Global stock:> 10 g(5 business days) | | |
Catalog IDEN300-188012 Product class
Building Block
Name(2R,3S)-2-methylmorpholine-3-carboxylic acid hydrochloride ACD numberMFCD28145077 CAS number1808578-40-6 Formula MW181.6 CLogP-1.032 Storage conditionsRT Transport conditionsNormal | Global stock:> 10 g(5 business days) USA Rush delivery(2 business days) available in Ohio stock: 1 g 1x0.002, 1x0.005, 1x0.01, 1x0.02, 1x0.025, 1x0.05, 1x0.1, 1x0.25, 1x0.5, 1x1 | | |
Catalog IDEN300-344717 Product class
Building Block
Namerac-(3R,6R)-6-methylmorpholine-3-carboxylic acid hydrochloride, trans ACD numberMFCD28954384 CAS number2059909-93-0 Formula MW181.6 CLogP-1.032 Storage conditionsRT Transport conditionsNormal | Global stock:4.7 g(5 business days) USA Rush delivery(2 business days) available in Ohio stock: 0.25 g 1x0.002, 1x0.005, 1x0.01, 1x0.02, 1x0.025, 1x0.05, 1x0.1, 1x0.25 | | |
Catalog IDEN300-1168847 Product class
Building Block
Namerac-(3R,5R)-5-methylmorpholine-3-carboxylic acid hydrochloride, cis ACD numberMFCD28246426 CAS number1807938-48-2 Formula MW181.6 CLogP-1.032 Storage conditionsRT Transport conditionsNormal | Global stock:> 10 g(5 business days) USA Rush delivery(2 business days) available in Ohio stock: 1 g 1x0.25, 1x0.5, 1x1EU Rush delivery(1 g)(2 business days) 1x0.25, 1x0.5, 1x1 | | |
Catalog IDEN300-6764094 Product class
Building Block
Namerac-(2R,4R)-4-chloropyrrolidine-2-carboxylic acid hydrochloride, cis ACD numberMFCD31915836 CAS number2309431-84-1 Formula MW186.0 CLogP-1.88 Storage conditionsRT Transport conditionsNormal | Global stock:> 10 g(5 business days) USA Rush delivery(2 business days) available in Ohio stock: 1 g 1x0.25, 1x0.5, 1x1 | | |
Catalog IDEN300-264302 Product class
Building Block
Name3-(piperidin-4-yl)prop-2-ynoic acid hydrochloride ACD numberMFCD29991443 CAS number1955530-40-1 Formula MW189.6 CLogP-2.112 Storage conditionsRT Transport conditionsNormal | Global stock:> 10 g(5 business days) USA Rush delivery(2 business days) available in Ohio stock: 5 g 1x0.25, 1x0.5, 1x1, 1x2.5, 1x5 | | |
Catalog IDEN300-298246 Product class
Building Block
Name3-(piperidin-3-yl)prop-2-ynoic acid hydrochloride ACD numberMFCD29991818 CAS number1955523-88-2 Formula MW189.6 CLogP-2.062 Storage conditionsRT Transport conditionsNormal | Global stock:> 10 g(5 business days) USA Rush delivery(2 business days) available in Ohio stock: 5 g 1x0.25, 1x0.5, 1x1, 1x2.5, 1x5 | | |
Catalog IDEN300-131172 Product class
Building Block
Name3-phenylpyrrolidine-2-carboxylic acid, Mixture of diastereomers ACD numberMFCD01191420 CAS number3005-68-3 Formula MW191.2 CLogP-1.555 Storage conditionsRT Transport conditionsNormal | Global stock:1.6 g(5 business days) USA Rush delivery(2 business days) available in Ohio stock: 1 g 1x0.25, 1x0.5, 1x1 | | |
Catalog IDEN300-43003 Product class
Building Block
Name2-azabicyclo[2.2.2]octane-1-carboxylic acid hydrochloride ACD number CAS number1156078-42-0 Formula MW191.7 CLogP0.853 Storage conditionsRT Transport conditionsNormal | Global stock:> 10 g(5 business days) USA Rush delivery(2 business days) available in New Jersey stock: 1 g 1x0.25, 1x0.5, 1x1EU Rush delivery(1 g)(2 business days) 1x0.25, 1x0.5, 1x1 | | |
Catalog IDEN300-1266430 Product class
Building Block
Namerac-(1R,3aR,6aS)-octahydrocyclopenta[c]pyrrole-1-carboxylic acid hydrochloride ACD number CAS number2220172-17-6 Formula MW191.7 CLogP-1.54 Storage conditionsRT Transport conditionsNormal | Global stock:> 10 g(5 business days) USA Rush delivery(2 business days) available in Ohio stock: 5 g 1x0.25, 1x0.5, 1x1, 1x2.5, 1x5 | | |
Catalog IDEN300-253656 Product class
Building Block
Name6-azaspiro[2.5]octane-1-carboxylic acid hydrochloride ACD numberMFCD18071370 CAS number1332530-45-6 Formula MW191.7 CLogP-2.308 Storage conditionsRT Transport conditionsNormal | Global stock:> 10 g(5 business days) USA Rush delivery(2 business days) available in Ohio stock: 5 g 1x0.25, 1x0.5, 1x1, 1x2.5, 1x5 | | |
Catalog IDEN300-7441792 Product class
Building Block
Name6-azaspiro[2.5]octane-5-carboxylic acid hydrochloride ACD numberMFCD31744411 CAS number2227204-75-1 Formula MW191.7 CLogP-1.54 Storage conditionsRT Transport conditionsNormal | USA Rush delivery(2 business days) available in New Jersey stock: 1 g 1x0.002, 1x0.005, 1x0.01, 1x0.02, 1x0.025, 1x0.05, 1x0.1, 1x0.25, 1x0.5, 1x1 | | |
Catalog IDEN300-26623742 Product class
Building Block
Name5-azaspiro[3.4]octane-6-carboxylic acid hydrochloride ACD number CAS number Formula MW191.7 CLogP-1.54 Storage conditionsRT Transport conditionsNormal | Global stock:> 10 g(5 business days) USA Rush delivery(2 business days) available in New Jersey stock: 1 g 1x0.25, 1x0.5, 1x1 | | |
Catalog IDEN300-1272862 Product class
Building Block
Namerac-methyl (1R,5R)-2-azabicyclo[3.2.0]heptane-1-carboxylate hydrochloride, cis ACD numberMFCD31629030 CAS number2155840-01-8 Formula MW191.7 CLogP0.579 Storage conditionsRT Transport conditionsNormal | Global stock:> 10 g(5 business days) USA Rush delivery(2 business days) available in Ohio stock: 1 g 1x0.002, 1x0.005, 1x0.01, 1x0.02, 1x0.025, 1x0.05, 1x0.1, 1x0.25, 1x0.5, 1x1 | | |
Catalog IDEN300-7539752 Product class
Building Block
Namerac-(1R,6S)-2-azabicyclo[4.2.0]octane-1-carboxylic acid hydrochloride, cis ACD number CAS number Formula MW191.7 CLogP0.853 Storage conditionsRT Transport conditionsNormal | Global stock:> 10 g(5 business days) USA Rush delivery(2 business days) available in New Jersey stock: 1 g 1x0.002, 1x0.005, 1x0.01, 1x0.02, 1x0.025, 1x0.05, 1x0.1, 1x0.25, 1x0.5, 1x1 | | |
Catalog IDEN300-7894437 Product class
Building Block
Namemethyl 2-azabicyclo[2.2.1]heptane-1-carboxylate hydrochloride ACD numberMFCD24508252 CAS number Formula MW191.7 CLogP0.579 Storage conditionsRT Transport conditionsNormal | Global stock:> 10 g(5 business days) | | |
Catalog IDEN300-645522 Product class
Building Block
Namerac-(3aR,6aR)-hexahydro-2H-furo[3,2-b]pyrrole-5-carboxylic acid hydrochloride ACD number CAS number2137432-91-6 Formula MW193.6 CLogP-2.084 Storage conditionsRT Transport conditionsNormal | Global stock:> 10 g(5 business days) USA Rush delivery(2 business days) available in Ohio stock: 1 g 1x0.25, 1x0.5, 1x1 | | |
Catalog IDEN300-181119 Product class
Building Block
Name4,4-dimethylpiperidine-2-carboxylic acid hydrochloride ACD numberMFCD28064046 CAS number1803560-90-8 Formula MW193.7 CLogP-0.816 Storage conditionsRT Transport conditionsNormal | Global stock:6.7 g(5 business days) | | |
Catalog IDEN300-182237 Product class
Building Block
Name3,3-dimethylpiperidine-2-carboxylic acid hydrochloride ACD numberMFCD28064075 CAS number1628734-55-3 Formula MW193.7 CLogP-0.816 Storage conditionsRT Transport conditionsNormal | Global stock:> 10 g(5 business days) EU Rush delivery(1 g)(2 business days) 1x0.25, 1x0.5, 1x1 | | |
Catalog IDEN300-269292 Product class
Building Block
Name4-phosphonopyrrolidine-2-carboxylic acid ACD numberMFCD24514943 CAS number1822542-39-1 Formula MW195.1 CLogP-2.208 Storage conditionsRT Transport conditionsNormal | Global stock:0.9 g(5 business days) USA Rush delivery(2 business days) available in Ohio stock: 0.25 | |
