Proline analogues
L-Proline has a unique role in protein structure in particular in the formation of B-turns. It has both a secondary nucleophilic amine and a carboxylic acid group, which can act as a Brønsted acid. Thus close analogues are of particular interest. The EnamineStore offers many proline analogues, some with additional conformational constraints like fused, spiro or aza-bicyclo systems. Furthermore there are examples of oxa-systems like the 2-oxa-7-azaspiro[4.4]nonane. To see selected examples, browse compounds below:
| Structure | Product info | Availability | Quantity / Price |
|---|---|---|---|
Catalog IDEN300-74879 Product class
Building Block
Nameazetidine-3-carboxylic acid ACD numberMFCD00191763 CAS number36476-78-5 Formula MW101.1 CLogP-2.664 Storage conditionsRT Transport conditionsNormal | Purity: 95%Global stock:2.8 g(5 business days) |  | |
Catalog IDEN300-263502 Product class
Building Block
Namerac-(3aR,6aR)-5-[(tert-butoxy)carbonyl]-hexahydro-1H-furo[3,4-c]pyrrole-3a-carboxylic acid ACD number CAS number1251019-97-2 Formula MW257.3 CLogP1.985 Storage conditionsRT Transport conditionsNormal | Purity: 95%Global stock:0.1 g(5 business days) | | |
Catalog IDEN300-383912 Product class
Building Block
Namebenzyl (2S,3aS,6aS)-octahydrocyclopenta[b]pyrrole-2-carboxylate hydrochloride ACD numberMFCD04974076 CAS number87269-87-2 Formula MW281.8 CLogP2.849 Storage conditions+4 Transport conditionsNormal | Purity: 95%Global stock:2.4 g(5 business days) | | |
Catalog IDEN300-1709414 Product class
Building Block
Name4-METHYLAZETIDINE-2-CARBOXYLIC ACID ACD numberMFCD24498411 CAS number1779725-63-1 Formula MW115.1 CLogP-2.453 Storage conditions+4 Transport conditionsNormal | USA Rush delivery(2 business days) available in New Jersey stock : 1x1 g | | |
Catalog IDEN300-6479762 Product class
Building Block
Namerac-(2R,4S)-4-methylazetidine-2-carboxylic acid, trans ACD numberMFCD31700188 CAS number2237226-49-0 Formula MW115.1 CLogP-2.453 Storage conditions+4 Transport conditionsNormal | USA Rush delivery(2 business days) available in New Jersey stock : 1x1 g | | |
Catalog IDEN300-58616 Product class
Building Block
Name(1S,5R)-2-azabicyclo[3.1.0]hexane-1-carboxylic acid ACD numberMFCD08436669 CAS number1212822-41-7 Formula MW127.1 CLogP-0.265 Storage conditionsRT Transport conditionsNormal | Out of stock 20 working days | | |
Catalog IDEN300-144929 Product class
Building Block
Name3-azabicyclo[3.1.0]hexane-1-carboxylic acid ACD numberMFCD19159829 CAS number63618-04-2 Formula MW127.1 CLogP-2.577 Storage conditionsRT Transport conditionsNormal | Out of stock 20 working days | | |
Catalog IDEN300-146494 Product class
Building Block
Name(1R,3S,5R)-2-azabicyclo[3.1.0]hexane-3-carboxylic acid ACD numberMFCD09040606 CAS number214193-12-1 Formula MW127.1 CLogP-2.428 Storage conditionsRT Transport conditionsNormal | Out of stock 20 working days | | |
Catalog IDEN300-28750 Product class
Building Block
Name2-azabicyclo[2.1.1]hexane-1-carboxylic acid ACD number CAS number73550-56-8 Formula MW127.1 CLogP-0.265 Storage conditionsRT Transport conditionsNormal | Out of stock 20 working days | | |
Catalog IDEN300-145230 Product class
Building Block
Name(1R,5S,6R)-3-azabicyclo[3.1.0]hexane-6-carboxylic acid ACD numberMFCD22395324 CAS number1212822-57-5 Formula MW127.1 CLogP-2.574 Storage conditionsRT Transport conditionsNormal | Out of stock 20 working days | | |
Catalog IDEN300-68611 Product class
Building Block
Name3-methylpyrrolidine-3-carboxylic acid ACD numberMFCD05663313 CAS number885953-27-5 Formula MW129.2 CLogP-2.239 Storage conditionsRT Transport conditionsNormal | USA Rush delivery(2 business days) available in New Jersey stock : 2x1 g | | |
Catalog IDEN300-206455 Product class
Building Block
Name(2S,5S)-5-methylpyrrolidine-2-carboxylic acid ACD numberMFCD19217648 CAS number49669-55-8 Formula MW129.2 CLogP-1.894 Storage conditionsRT Transport conditionsNormal | Out of stock 20 working days | | |
Catalog IDEN300-174676 Product class
Building Block
Name(2S)-2-methylpyrrolidine-2-carboxylic acid ACD numberMFCD01318647 CAS number42856-71-3 Formula MW129.2 CLogP0.499 Storage conditionsRT Transport conditionsNormal | USA Rush delivery(2 business days) available in New Jersey stock : 1x5 g | | |
Catalog IDEN300-50592 Product class
Building Block
Name2-(pyrrolidin-2-yl)acetic acid ACD numberMFCD08458431 CAS number56879-46-0 Formula MW129.2 CLogP-2.139 Storage conditionsRT Transport conditionsNormal | Out of stock 20 working days | | |
Catalog IDEN300-116707 Product class
Building Block
Name3-methylpyrrolidine-2-carboxylic acid ACD numberMFCD11557236 CAS number3005-84-3 Formula MW129.2 CLogP-1.894 Storage conditionsRT Transport conditionsNormal | Out of stock 20 working days | | |
Catalog IDEN300-80864 Product class
Building Block
Name2-methylpyrrolidine-2-carboxylic acid ACD numberMFCD01318632 CAS number16277-06-8 Formula MW129.2 CLogP0.499 Storage conditionsRT Transport conditionsNormal | Out of stock 20 working days | | |
Catalog IDEN300-6477839 Product class
Building Block
Namerac-(2R,3S)-3-fluoropyrrolidine-2-carboxylic acid, trans ACD numberMFCD32066778 CAS number2199280-76-5 Formula MW133.1 CLogP-2.62 Storage conditionsRT Transport conditionsNormal | EU Rush delivery : (2 business days) 1x0.101 gUSA Rush delivery(2 business days) available in New Jersey stock : 1x0.25 g | | |
Catalog IDEN300-204156 Product class
Building Block
Name2-{2-azabicyclo[2.1.1]hexan-1-yl}acetic acid ACD numberMFCD19225804 CAS number721394-81-6 Formula MW141.2 CLogP-2.384 Storage conditionsRT Transport conditionsNormal | Out of stock 20 working days | | |
Catalog IDEN300-57845 Product class
Building Block
Name7-azabicyclo[2.2.1]heptane-1-carboxylic acid ACD numberMFCD19690726 CAS number331258-38-9 Formula MW141.2 CLogP0.294 Storage conditionsRT Transport conditionsNormal | Out of stock 20 working days | | |
Catalog IDEN300-142601 Product class
Building Block
Name2-azaspiro[3.3]heptane-6-carboxylic acid ACD numberMFCD18837596 CAS number1172691-93-8 Formula MW141.2 CLogP-3.097 Storage conditionsRT Transport conditionsNormal | Out of stock 20 working days | | |
Catalog IDEN300-148045 Product class
Building Block
Name(1S,4R)-2-azabicyclo[2.2.1]heptane-1-carboxylic acid ACD numberMFCD08444726 CAS number882182-44-7 Formula MW141.2 CLogP0.294 Storage conditionsRT Transport conditionsNormal | Out of stock 20 working days | | |
Catalog IDEN300-125410 Product class
Building Block
Name3-azabicyclo[3.2.0]heptane-1-carboxylic acid ACD numberMFCD28968118 CAS number1804129-89-2 Formula MW141.2 CLogP-2.018 Storage conditionsRT Transport conditionsNormal | Out of stock 20 working days | | |
Catalog IDEN300-147163 Product class
Building Block
Name3-azabicyclo[3.1.1]heptane-6-carboxylic acid ACD numberMFCD23106436 CAS number1240562-06-4 Formula MW141.2 CLogP-2.245 Storage conditionsRT Transport conditionsNormal | Out of stock 20 working days | | |
Catalog IDEN300-188013 Product class
Building Block
Name(2R,3S)-2-methylmorpholine-3-carboxylic acid ACD numberMFCD13176508 CAS number1212252-84-0 Formula MW145.2 CLogP-1.032 Storage conditionsRT Transport conditionsNormal | Out of stock 20 working days | | |
Catalog IDEN300-89756 Product class
Building Block
Name4,4-difluoropyrrolidine-2-carboxylic acid ACD numberMFCD13186733 CAS number1073555-68-6 Formula MW151.1 CLogP-1.227 Storage conditionsRT Transport conditionsNormal | Out of stock 20 working days | | |
Catalog IDEN300-146263 Product class
Building Block
Name6-azaspiro[2.5]octane-1-carboxylic acid ACD numberMFCD17012789 CAS number1242028-68-7 Formula MW155.2 CLogP-2.308 Storage conditionsRT Transport conditionsNormal | Out of stock 20 working days | | |
Catalog IDEN300-130329 Product class
Building Block
Nameoctahydrocyclopenta[c]pyrrole-3a-carboxylic acid, cis ACD numberMFCD05663151 CAS number885956-39-8 Formula MW155.2 CLogP-1.459 Storage conditions+4 Transport conditionsNormal | Out of stock 20 working days | | |
Catalog IDEN300-345278 Product class
Building Block
Nameoctahydrocyclopenta[b]pyrrole-3a-carboxylic acid ACD numberMFCD30537767 CAS number1502028-23-0 Formula MW155.2 CLogP-1.885 Storage conditionsRT Transport conditionsNormal | Out of stock 20 working days | | |
Catalog IDEN300-43005 Product class
Building Block
Name2-azabicyclo[2.2.2]octane-1-carboxylic acid ACD numberMFCD20542906 CAS number1124344-72-4 Formula MW155.2 CLogP0.853 Storage conditionsRT Transport conditionsNormal | Out of stock 20 working days | | |
Catalog IDEN300-135608 Product class
Building Block
Name3,3-dimethylpiperidine-2-carboxylic acid ACD numberMFCD20640452 CAS number129769-02-4 Formula MW157.2 CLogP-0.816 Storage conditionsRT Transport conditionsNormal | Out of stock 20 working days | | |
Catalog IDEN300-109348 Product class
Building Block
Name4,4-dimethylpiperidine-2-carboxylic acid ACD numberMFCD20641837 CAS number137734-86-2 Formula MW157.2 CLogP-0.816 Storage conditionsRT Transport conditionsNormal | Out of stock 20 working days | | |
Catalog IDEN300-373686 Product class
Building Block
Namerac-(2R,4S,6R)-4,6-dimethylpiperidine-2-carboxylic acid ACD number CAS number2089245-52-1 Formula MW157.2 CLogP-0.816 Storage conditionsRT Transport conditionsNormal | USA Rush delivery(2 business days) available in New Jersey stock : 1x1 g | | |
Catalog IDEN300-1477614 Product class
Building Block
Name6-ETHYLPIPERIDINE-2-CARBOXYLIC ACID ACD numberMFCD26045085 CAS number1037471-93-4 Formula MW157.2 CLogP-0.806 Storage conditionsRT Transport conditionsNormal | USA Rush delivery(2 business days) available in New Jersey stock : 1x1 g | | |
Catalog IDEN300-217759 Product class
Building Block
Name2-(methoxymethyl)pyrrolidine-2-carboxylic acid ACD numberMFCD26082324 CAS number1564868-48-9 Formula MW159.2 CLogP0.439 Storage conditionsRT Transport conditionsNormal | Out of stock 20 working days | | |
Catalog IDEN300-152014 Product class
Building Block
Name1-oxo-1lambda4-thiomorpholine-3-carboxylic acid ACD numberMFCD21129256 CAS number156474-26-9 Formula MW163.2 CLogP-2.218 Storage conditionsRT Transport conditionsNormal | Out of stock 20 working days | | |
Catalog IDEN300-85729 Product class
Building Block
Name(1R,3S,5R)-2-azabicyclo[3.1.0]hexane-3-carboxylic acid hydrochloride ACD numberMFCD09971683 CAS number1807939-32-7 Formula MW163.6 CLogP-2.428 Storage conditionsRT Transport conditionsNormal | Out of stock 20 working days | | |
Catalog IDEN300-35220 Product class
Building Block
Name2-azabicyclo[2.1.1]hexane-1-carboxylic acid hydrochloride ACD number CAS number116129-07-8 Formula MW163.6 CLogP-0.265 Storage conditionsRT Transport conditionsNormal | USA Rush delivery(2 business days) available in New Jersey stock : 1x1 g | | |
Catalog IDEN300-88835 Product class
Building Block
Name3-azabicyclo[3.1.0]hexane-1-carboxylic acid hydrochloride ACD numberMFCD11858206 CAS number1181458-33-2 Formula MW163.6 CLogP-2.577 Storage conditionsRT Transport conditionsNormal | Out of stock 20 working days | | |
Catalog IDEN300-88447 Product class
Building Block
Namerac-(1R,5S,6R)-3-azabicyclo[3.1.0]hexane-6-carboxylic acid hydrochloride ACD numberMFCD11099877 CAS number1212105-25-3 Formula MW163.6 CLogP-2.574 Storage conditionsRT Transport conditionsNormal | | ||
Catalog IDEN300-53419 Product class
Building Block
Name(1S,5R)-2-azabicyclo[3.1.0]hexane-1-carboxylic acid hydrochloride ACD numberMFCD08460279 CAS number1212477-19-4 Formula MW163.6 CLogP-0.265 Storage conditionsRT Transport conditionsNormal | Out of stock 20 working days | | |
Catalog IDEN300-82687 Product class
Building Block
Name4,4-difluoropiperidine-3-carboxylic acid ACD numberMFCD18909832 CAS number1303973-15-0 Formula MW165.1 CLogP-1.913 Storage conditionsRT Transport conditionsNormal | Out of stock 20 working days | | |
Catalog IDEN300-224579 Product class
Building Block
Name3-(difluoromethyl)pyrrolidine-3-carboxylic acid ACD numberMFCD29033965 CAS number1820674-05-2 Formula MW165.1 CLogP-2.193 Storage conditionsRT Transport conditionsNormal | Out of stock 20 working days | | |
Catalog IDEN300-86504 Product class
Building Block
Name(3S,4S)-4-(difluoromethyl)pyrrolidine-3-carboxylic acid ACD numberMFCD20441570 CAS number1486470-42-1 Formula MW165.1 CLogP-3.093 Storage conditionsRT Transport conditionsNormal | Out of stock 20 working days | | |
Catalog IDEN300-45049 Product class
Building Block
Name1,1-dioxo-1,2-thiazolidine-3-carboxylic acid ACD numberMFCD07369945 CAS number1146957-01-8 Formula MW165.2 CLogP-1.109 Storage conditions+4 Transport conditionsNormal | | ||
Catalog IDEN300-114208 Product class
Building Block
Name2-(pyrrolidin-2-yl)acetic acid hydrochloride ACD numberMFCD11506301 CAS number71985-79-0 Formula MW165.6 CLogP-2.139 Storage conditionsRT Transport conditionsNormal | USA Rush delivery(2 business days) available in New Jersey stock : 1x1 g | | |
Catalog IDEN300-114790 Product class
Building Block
Name2-methylpyrrolidine-2-carboxylic acid hydrochloride ACD numberMFCD22565928 CAS number1423025-85-7 Formula MW165.6 CLogP0.499 Storage conditionsRT Transport conditionsNormal | | ||
Catalog IDEN300-139285 Product class
Building Block
Name3-methylpyrrolidine-2-carboxylic acid hydrochloride, Mixture of diastereomers ACD numberMFCD26936039 CAS number14704-69-9 Formula MW165.6 CLogP-1.894 Storage conditionsRT Transport conditionsNormal | EU Rush delivery : (2 business days) 1x1 gUSA Rush delivery(2 business days) available in New Jersey stock : 1x5 g | | |
Catalog IDEN300-331563 Product class
Building Block
Name3,3-dimethylazetidine-2-carboxylic acid hydrochloride ACD numberMFCD30497784 CAS number2059936-62-6 Formula MW165.6 CLogP-1.934 Storage conditionsRT Transport conditionsNormal | | ||
Catalog IDEN300-105554 Product class
Building Block
Name3-methylpyrrolidine-3-carboxylic acid hydrochloride ACD numberMFCD22369922 CAS number1222503-25-4 Formula MW165.6 CLogP-2.239 Storage conditionsRT Transport conditionsNormal | | ||
Catalog IDEN300-206454 Product class
Building Block
Name5-methylpyrrolidine-2-carboxylic acid hydrochloride, cis ACD numberMFCD28656971 CAS number38228-14-7 Formula MW165.6 CLogP-1.894 Storage conditionsRT Transport conditionsNormal | Out of stock 20 working days | |
