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Glucocorticoid receptor

StructureProduct infoAvailabilityQuantity / Price
BRC0866
Product IDBRC0866
Product classBioreference compound
CAS number57-83-0
MW314.5
Synonyms
BP 14, NSC-64377, NSC-9704, U 3672
Transport conditionsNormal
Restrictions Included in California Proposition 65 list  WARNING! This product contains a chemical known to the State of California to cause health damage. For more information go to www.P65Warnings.ca.gov.

Progesterone

Progesterone is steroid hormone produced by the corpus luteum. It is endogenous progesterone receptor (PR) agonist (EC50 = 0.5 nM).

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BRC0048
Product IDBRC0048
Product classBioreference compound
CAS number976-71-6
MW340.5
Synonyms
Phanurane, Aldadiene, Luvion, Aldadiene,
Transport conditionsNormal

Canrenone

Mineralocorticoid receptor antagonist. Active metabolite of spironolactone. A potassium sparing diuretic that acts by antagonism of aldosterone in the distal renal tubules. It is used mainly in the treatment of refractory edema in patients with congestive heart failure, nephrotic syndrome, or hepatic cirrhosis. Its effects on the endocrine system are utilized in the treatments of hirsutism and acne but they can lead to adverse effects.

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BRC0106
Product IDBRC0106
Product classBioreference compound
CAS number50-24-8
MW360.4
Synonyms
Meticortelone, Predonine, Metacortandralone, Deltacortril, Hydeltra
Transport conditionsNormal

Prednisolone

Prednisolone is a synthetic glucocorticoid used as antiinflammatory or immunosuppressive agent.

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BRC0836
Product IDBRC0836
Product classBioreference compound
CAS number50-23-7
MW362.5
Synonyms
NSC-10483
Transport conditionsNormal

Hydrocortisone

Hydrocortisone is steroid hormone of the adrenal cortex with anti-inflammatory properties.

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BRC0488
Product IDBRC0488
Product classBioreference compound
CAS number71653-63-9
MW367.3
Synonyms
Foridon, Foridone, PP 1466
Transport conditionsNormal

Riodipine

Riodipine is a calcium channel blocker.

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BRC0844
Product IDBRC0844
Product classBioreference compound
CAS number378-44-9
MW392.5
Synonyms
NSC-39470, SCH 4831
Transport conditionsNormal

Betamethasone

Betamethasone is a glucocorticoid receptor agonist.

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BRC0352
Product IDBRC0352
Product classBioreference compound
CAS number50-02-2
MW392.5
Synonyms
MK 125, NSC 34521
Transport conditionsNormal

Dexamethasone

Dexamethasone is an antiinflammatory glucocorticoid that induces the production of phospholipase A2 inhibitory protein (lipocortin). It also inhibits induction of nitric oxide synthase (IC50=5 nM). Dexamethasone has been shown to cause reduction in cyclin A and Cdk2 activity, inhibition of G1/S transition in osteoblasts and inhibition of phosphorylation of Rb protein in vitro.

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BRC0072
Product IDBRC0072
Product classBioreference compound
CAS number52-01-7
MW416.6
Synonyms
Aldactone, Verospiron, Spiroctan
Transport conditionsNormal
Restrictions Included in California Proposition 65 list  WARNING! This product contains a chemical known to the State of California to cause cancer. For more information go to www.P65Warnings.ca.gov.

Spironolactone

Spironolactone is a potent antagonist of the androgen receptor with IC50 of 77 nM. Spironolactone is a synthetic 17-lactone steroid which is a renal competitive aldosterone antagonist in a class of pharmaceuticals called potassium-sparing diuretics.

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BRC0296
Product IDBRC0296
Product classBioreference compound
CAS number84371-65-3
MW429.6
Synonyms
RU 486, RU 38486, C-1073
Transport conditionsNormal

Mifepristone

A progestational and glucocorticoid hormone antagonist.

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BRC0027
Product IDBRC0027
Product classBioreference compound
CAS number126784-99-4
MW475.6
Synonyms
EllaOne, Ella, CDB 2914,
Transport conditionsNormal

Ulipristal acetate

Ulipristal is a selective, reversible progestin receptor modulator and its tissue targets include the uterus, cervix, ovaries, and hypothalamus. Ulipristal may act as an agonist or antagonist in the presence or absence of progesterone based on the tissue target.

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