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Anti-Inflammatory

StructureProduct infoAvailabilityQuantity / Price
BRC0993
Product IDBRC0993
Product classBioreference compound
CAS number65-45-2
MW137.1
Synonyms
OHB;
Transport conditionsNormal

Salicylamide

Salicylamide is an analgesic and antipyretic agent. Its medicinal uses are similar to those of aspirin.

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BRC0859
Product IDBRC0859
Product classBioreference compound
CAS number69-72-7
MW138.1
Synonyms
FEMA NO. 3985; K-557; NSC-180;
Transport conditionsNormal

Salicylic acid

Salicylic acid is bacteriostatic, fungicide and keratolytic agent. It is directly and irreversibly inhibits the activity of COX-1 and COX-2 to decrease the formation of precursors of prostaglandins and thromboxanes from arachidonic acid.

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BRC1058
Product IDBRC1058
Product classBioreference compound
CAS number25769-03-3
MW147.2
Synonyms
Pyrrolidinecarbodithioic acid; Tetramethylenedithiocarbamic acid;
Transport conditionsNormal

PDTC

PDTC is a potent inhibitor of Nuclear Factor κB (IC50 = 3.35 µM). It prevents the increase in NO-synthase mRNA by interleukin-1, without affecting the formation of NO-synthase mRNA produced by cAMP.

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BRC0168
Product IDBRC0168
Product classBioreference compound
CAS number89-57-6
MW153.1
Synonyms
5-ASA, Asacol, Asacolitin, Canasa, Claversal, Fisalamine, Iialda, Lixacol, m-Aminosalicylic acid, P-Aminosalicylsaeure, Pentasa, Rowasa, Salofalk
Transport conditionsNormal

Mesalazine

An anti-inflammatory agent, structurally related to the salicylates, which is active in inflammatory bowel disease. It is considered to be the active moiety of sulphasalazine. 

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BRC1035
Product IDBRC1035
Product classBioreference compound
CAS number41862-09-3
MW155.2
Synonyms
Transport conditionsNormal

6-Amino-1-ethyluracil

6-Amino-1-ethyluracil is A2B adenosine receptor antagonist, may used in prevention and treatment of liver disease.

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BRC1290
Product IDBRC1290
Product classBioreference compound
CAS number97-59-6
MW158.1
Synonyms
NSC 7606; Psoralon; SD 101; Sebical;
Transport conditionsNormal

Allantoin

Allantoin is a purine metabolite via the uric acid pathway. It may be a useful biomarker for oxidative stress.

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BRC1041
Product IDBRC1041
Product classBioreference compound
CAS number490-91-5
MW164.2
Synonyms
NSC 2228;
Transport conditionsNormal

Thymoquinone

Thymoquinone is a natural phytochemical with anti-inflammatory effects, blocking the synthesis of leukotrienes. It inhibits the growth of leukemia cells (IC50 = 1.5 μg/ml), inducing apoptosis by down-regulating the expression of Bcl-2 while up-regulating Bax expression.

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BRC1066
Product IDBRC1066
Product classBioreference compound
CAS number498-02-2
MW166.2
Synonyms
NSC 209524; NSC 2146;
Transport conditionsNormal

Apocynin

Apocynin is a methoxy-substituted catechol that is commonly used as a selective NADPH-oxidase inhibitor with IC50 of 10 μM. Acts as an antioxidant in endothelial cells and vascular smooth muscle cells.

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BRC1078
Product IDBRC1078
Product classBioreference compound
CAS number149-91-7
MW170.1
Synonyms
NSC 20103; NSC 674319;
Transport conditionsNormal

Gallic acid

Gallic acid is an anti-inflammatory agent and cyclooxygenase inhibitor found in plants and has been shown to Induce apoptosis in human lung cancer cells. It is often used as a standard for determining the phenol content of various analytes by the Folin-Ciocalteau assay where results are reported in gallic acid equivalents.

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BRC0936
Product IDBRC0936
Product classBioreference compound
CAS number50-78-2
MW180.2
Synonyms
BAY1019036; NSC-27223; NSC-406186; ASA; Aspirin;
Transport conditionsNormal
Restrictions Included in California Proposition 65 list  WARNING! This product contains a chemical known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

Acetylsalicylic acid

Acetylsalicylic acid is an anti-inflammatory and antipyretic agent and acts as the inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. It also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis.

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BRC1022
Product IDBRC1022
Product classBioreference compound
CAS number331-39-5
MW180.2
Synonyms
DHCA; NSC 57197; NSC 623438;
Transport conditionsNormal
Restrictions Included in California Proposition 65 list  WARNING! This product contains a chemical known to the State of California to cause cancer. For more information go to www.P65Warnings.ca.gov.

Caffeic Acid

Caffeic Acid is an endogenous phenolic phytochemical compound. It non-competitive inhibits a number of lipoxygenases such as 5-LO (5-lipoxygenase), and 12-LO (12-lipoxygenase) inhibiting leukotriene synthesis resulting in further inhibition of immunoregulation. Caffeic Acid has also been shown to inhibit arachidonic acid metabolism in platelets at high doses. It has been observed to stimulate prostaglandin synthesis at high doses. It is an inhibitor of GST, ODC, Tyk and Xanthine Oxidase.

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BRC1121
Product IDBRC1121
Product classBioreference compound
CAS number123-99-9
MW188.2
Synonyms
Finacea; Lepargylic acid; NSC 19493; Skinoren; ZK 62498;
Transport conditionsNormal

Azelaic Acid

Azelaic acid is an anti-inflammatory agent. It directly inhibits kallikrein 5 (KLK5), downregulating expression of KLK5, toll-like receptor 2 (TLR 2), and cathelicidin, and suppresses activity of serine proteases in vitro, in vivo, and in clinical settings.

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BRC0978
Product IDBRC0978
Product classBioreference compound
CAS number60-80-0
MW188.2
Synonyms
Transport conditionsNormal

Antipyrine

Antipyrine is an analgesic and antipyretic. It inhibits isoforms of cyclooxygenase, COX-1, COX-2, and COX-3 enzymes involved in prostaglandin (PG) synthesis. Antipyrine is often used in testing the effects of other drugs or diseases on drug-metabolizing enzymes in the liver.

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BRC1244
Product IDBRC1244
Product classBioreference compound
CAS number127657-29-8
MW205.2
Synonyms
Reolase;
Transport conditionsNormal

(R, S) - Telmesteine

Telmesteine is a mucolytic agent.

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BRC0827
Product IDBRC0827
Product classBioreference compound
CAS number51146-56-6
MW206.3
Synonyms
d-ibuproten; S(+)-ibuprofen;
Transport conditionsNormal

Dexibuprofen

Dexibuprofen is a non-steroidal anti-inflammatory drug. It is a pharmacologically effective enantiomer of racemic ibuprofen that differs in physicochemical properties.

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BRC0814
Product IDBRC0814
Product classBioreference compound
CAS number15687-27-1
MW206.3
Synonyms
NSC 256857; U-18753;
Transport conditionsNormal

Ibuprofen

Ibuprofen is a nonsteroidal anti-inflammatory agent with analgesic and antipyretic properties. It is a non-selective, reversible COX inhibitor (IC50 for human recombinant COX-1 and COX-2 are 2.6 and 1.53 µM, respectively).

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BRC0297
Product IDBRC0297
Product classBioreference compound
CAS number57-67-0
MW214.2
Synonyms
Guanicil, RP 2275
Transport conditionsNormal

Sulfaguanidine

Sulfaguanidine is a sulfonamide used as an anti-infective agent. Is the first sulfonamide designed to treat enteric infections.

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BRC0999
Product IDBRC0999
Product classBioreference compound
CAS number66-84-2
MW215.6
Synonyms
Chitosamine;
Transport conditionsNormal

Glucosamine Hydrochloride

Glucosamine is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids.

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BRC1139
Product IDBRC1139
Product classBioreference compound
CAS number496-67-3
MW223.1
Synonyms
Pivadorn; Somnurol; Upiol; Uvaleral;
Transport conditionsNormal

Bromisoval

Bromisoval is a sedative-hypnotic agent that is occasionally combined with non-steroidal anti-inflammatory drugs in over-the-counter products. It suppresses expression of many kinds of pro- and anti-inflammatory mediators in LPS- or interferon-γ activated alveolar and peritoneal macrophages. Bromisoval is used to treat anxiety.

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BRC0329
Product IDBRC0329
Product classBioreference compound
CAS number66000-40-6
MW229.2
Synonyms
Transport conditionsNormal

BW 755C

BW-755C is a dual inhibitor of both cyclooxygenase and lipoxygenase pathways. It exerts an anti-inflammatory effect by inhibiting the formation of prostaglandins and leukotrienes. The drug also enhances pulmonary hypoxic vasoconstriction and has a protective effect after myocardial ischemia.

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BRC0826
Product IDBRC0826
Product classBioreference compound
CAS number22204-53-1
MW230.3
Synonyms
RS-3540;
Transport conditionsNormal

Naproxen

Naproxen is a member of the arylacetic acid group of nonsteroidal anti-inflammatory drugs with analgesic and antipyretic properties. It is non-selective cyclooxygenase inhibitor. Has a neuroprotective role against colchicine-induced cognitive impairment and oxidative stress.

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BRC0187
Product IDBRC0187
Product classBioreference compound
CAS number111406-87-2
MW236.3
Synonyms
Zyflo, ICI D2138
Transport conditionsNormal
Restrictions Included in California Proposition 65 list  WARNING! This product contains a chemical known to the State of California to cause cancer and birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

Zileuton

Zileuton is an asthma drug that differs chemically and pharmacologically from other antiasthmatic agents. It blocks leukotriene synthesis by inhibiting 5-lipoxygenase, an enzyme of the eicosanoid synthesis pathway.

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BRC0971
Product IDBRC0971
Product classBioreference compound
CAS number61-68-7
MW241.3
Synonyms
CI-473; CN-35355; INF-3355; J2.344B; M01AG01;
Transport conditionsNormal

Mefenamic acid

Mefenamic acid is a member of the fenamate group of nonsteroidal anti-inflammatory drugs. It exhibits anti-inflammatory, analgesic, and antipyretic activities. Mefenamic acid is a noncompetitive inhibitor of 2-arachidonoylglycerol oxygenation and a competitive inhibitor of COX-2 oxygenation of arachidonic acid.

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BRC1049
Product IDBRC1049
Product classBioreference compound
CAS number486-66-8
MW254.2
Synonyms
Daidzin aglycone; FW 635I-1; Isoaurostatin; K 251b; NPI 031E;
Transport conditionsNormal

Daidzein

Daidzein is the aglucon of Daidzin, an inactive analog of Genistein, a tyrosine kinase inhibitor, that allows it to act as a negative control for such experiments. It is a phytoestrogen which may play a role in hormone-produced cancers.

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BRC1004
Product IDBRC1004
Product classBioreference compound
CAS number36330-85-5
MW254.3
Synonyms
CL 82,204;
Transport conditionsNormal

Fenbufen

Fenbufen is a non-steroidal anti-inflammatory drug. Used primarily to treat inflammation in osteoarthritis, ankylosing spondylitis, and tendinitis. It can also be used to relieve backaches, sprains, and fractures.

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BRC0718
Product IDBRC0718
Product classBioreference compound
CAS number22071-15-4
MW254.3
Synonyms
Orudis; Oruvail;
Transport conditionsNormal

Ketoprofen

Ketoprofen is a nonsteroidal anti-inflammatory agent with analgesic and antipyretic properties. It is used to treat rheumatoid arthritis, osteoarthritis, dysmenorrhea, and alleviate moderate pain. Ketoprofen is a non-selective NSAID exhibiting IC50 values of 0.5 µM and 2.33 µM for human recombinant COX-1 and COX-2, respectively.

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BRC0413
Product IDBRC0413
Product classBioreference compound
CAS number74103-06-3
MW255.3
Synonyms
Acular LS®, Acular PF®, RS 37619, Sprix®, Bedoral, Dolten,
Transport conditionsNormal

Ketorolac

Ketorolac is a nonsteroidal anti-inflammatory drug (NSAID) chemically related to indomethacin and tolmetin. Ketorolac tromethamine is a racemic mixture of [-]S- and [+]R-enantiomeric forms, with the S-form having analgesic activity.

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BRC0915
Product IDBRC0915
Product classBioreference compound
CAS number803647-40-7
MW265.3
Synonyms
Transport conditionsNormal

NSC 59984

NSC59984 restores wild-​type p53 signaling via p73 activation, specifically in mutant p53-​expressing colorectal cancer cells. It synergizes with CPT11 to induce cell death in mutant p53-​expressing colorectal cancer cells and inhibits mutant p53-​assocd. colon tumor xenograft growth in a p73-​dependent manner in vivo.

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BRC1050
Product IDBRC1050
Product classBioreference compound
CAS number485-72-3
MW268.3
Synonyms
Mycotech; NSC 93360; Biochanin B; Flavosil;
Transport conditionsNormal

Formononetin

Formononetin is an isoflavonoid phytoestrogenic compound, the precursor of daidzein. It acts as an agonist of the aryl hydrocarbon receptor (EC50 = 0.13 µM). Formononetin has been reported to possess antitumor and antiviral activity.

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BRC1295
Product IDBRC1295
Product classBioreference compound
CAS number51298-62-5
MW269.7
Synonyms
Transport conditionsNormal

L-NAME hydrochloride

L-NAME hydrochloride is a nonselective inhibitor of nitric oxide synthetases.

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BRC0203
Product IDBRC0203
Product classBioreference compound
CAS number108605-62-5
MW270.2
Synonyms
a 77-1726; Aubagio; HMR1726;
Transport conditionsNormal

(E, Z) - Teriflunomide

Teriflunomide is an immunomodulatory agent that decreases the amount of activated CNS lymphocytes, which results in anti-inflammatory and antiproliferative effects.

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BRC0758
Product IDBRC0758
Product classBioreference compound
CAS number53716-49-7
MW273.7
Synonyms
C 5720, Carprodyl, Imadyl, NSC 297935, Rimadyl, Ro 20-5720, Ro 20-5720/000
Transport conditionsNormal

Carprofen

Carprofen is a non-steroidal anti-inflammatory drug that selectively inhibits cyclooxygenase-2 (COX-2). It is no longer used in the clinical setting, but is approved for use in dogs.

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BRC0479
Product IDBRC0479
Product classBioreference compound
CAS number530-78-9
MW281.2
Synonyms
Arlef, CI 440, CN 27544, INF 1837, NSC 219007, NSC 82699
Transport conditionsNormal

Flufenamic acid

Flufenamic acid is an anthranilic acid-derived nonsteroidal anti-inflammatory drug (NSAID) thought to exert its actions by a prostanoid-independent mechanism.

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BRC0980
Product IDBRC0980
Product classBioreference compound
CAS number4394-00-7
MW282.2
Synonyms
Lopac-N-0630; UP 83; NFA; Niflugel; Actol; Donalgin; Nifluril;
Transport conditionsNormal

Niflumic Acid

Niflumic acid is a nonsteroidal anti-inflammatory fenamate, is a Ca2+-activated Cl- channel blocker. It inhibits both phospholipase A2 as well as COX-2.

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BRC0756
Product IDBRC0756
Product classBioreference compound
CAS number41340-25-4
MW287.4
Synonyms
Lodine, NIH 9918, NSC 282126, AY 24236
Transport conditionsNormal
Restrictions Included in California Proposition 65 list  WARNING! This product contains a chemical known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

Etodolac

Etodolac is a non-steroidal anti-inflammatory drug that selectively inhibits cyclooxygenase-2 (COX-2). It is an anti-inflammatory agent with analgesic and antipyretic properties.

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BRC0426
Product IDBRC0426
Product classBioreference compound
CAS number21256-18-8
MW293.3
Synonyms
WY-21743, Daypro, NSC 310839, Alvo
Transport conditionsNormal

Oxaprozin

Oxaprozin is a nonsteroidal anti-inflammatory drug (NSAID) with analgesic and antipyretic properties.

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BRC0989
Product IDBRC0989
Product classBioreference compound
CAS number15307-86-5
MW296.2
Synonyms
ISV-205;
Transport conditionsNormal

Diclofenac

Diclofenac is a nonsteroidal anti-inflammatory drug with analgesic and antipyretic properties. It inhibits both leukocyte migration and the enzyme cyclooxygenase (COX-1 and COX-2), leading to the peripheral inhibition of prostaglandin synthesis.

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BRC0359
Product IDBRC0359
Product classBioreference compound
CAS number50-33-9
MW308.4
Synonyms
Butazolidinel
Transport conditionsNormal

Phenylbutazone

Phenylbutazone is a compound of research interest as an anti-inflammatory and anti-proliferative agent.

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BRC0345
Product IDBRC0345
Product classBioreference compound
CAS number24237-54-5
MW316.4
Synonyms
Y-3642, Nonflamin, Dimaten
Transport conditionsNormal

Tinoridine

Tinoridine, also known as Y-3642, is a non-steroidal anti-inflammatory drug.

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BRC0166
Product IDBRC0166
Product classBioreference compound
CAS number67254-91-5
MW318.1
Synonyms
Meclofenamate, Arquel, Acide meclofenamique, Meclomen
Transport conditionsNormal

Meclofenamate sodium

A non-steroidal anti-inflammatory agent with antipyretic and antigranulation activities. It also inhibits prostaglandin biosynthesis.

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BRC1106
Product IDBRC1106
Product classBioreference compound
CAS number913548-29-5
MW319.4
Synonyms
APAU;
Transport conditionsNormal

AR-9281

AR-9281 is a soluble bifunctional epoxide hydrolase 2 inhibitor potentially for the treatment of hypertension and type 2 diabetes.

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BRC0193
Product IDBRC0193
Product classBioreference compound
CAS number129-20-4
MW324.4
Synonyms
USAF Ge-14;
Transport conditionsNormal

Oxyphenbutazone

Oxyphenbutazone is a metabolite of Phenylbutazone. It is described to produce anti-inflammatory effects and demonstrates inhibition of cytokine production.

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BRC0696
Product IDBRC0696
Product classBioreference compound
CAS number332939-46-5
MW326.8
Synonyms
Transport conditionsNormal

N-[(5-Chloro-8-hydroxyquinolin-7-yl)(phenyl)methyl]acetamide

The compound is inhibitor of HIV-1 integrase-lens epithelium-derived growth factor/p75 (IN-LEDGF/p75) interaction (IC50 = 3 µM).

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BRC0415
Product IDBRC0415
Product classBioreference compound
CAS number36322-90-4
MW331.4
Synonyms
Feldene; Larapam; NSC 666076; CP 16171; Bruxicam; Dolonex; Erazon; Improntal; Roxam; Roxiden; Sasulen; Solocalm; Trast;
Transport conditionsNormal

Piroxicam

Piroxicam is in a class of drugs called nonsteroidal anti-inflammatory drugs (NSAIDs). Piroxicam works by reducing hormones that cause inflammation and pain in the body.

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BRC1047
Product IDBRC1047
Product classBioreference compound
CAS number133039-73-3
MW338.2
Synonyms
LDN 0097519; Lagistase; C.I. 55005; C.I. 75270; Alizarin yellow;
Transport conditionsNormal

Ellagic Acid

Ellagic acid is selective ATP-competitive inhibitor of casein kinase 2. It exhibits antioxidant, antitumor and antiproliferative activity.

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BRC0447
Product IDBRC0447
Product classBioreference compound
CAS number918328-90-2
MW340.4
Synonyms
Transport conditionsNormal

pyrrolo[2,1-b]quinazoline-1,2,3,9-tetrahydro-9-oxo-N-methyl-N-(1-methyl-piperidinyl-4)-6-carboxamide

Inhibitor of glycosaminoglycan-mediated cell-cell interaction. In an assay, the compound inhibited 16% of MCP-3 chemokine binding to heparin at a concentration of 37.5 μmol/l [WO2007/771 A2, 2007]. The compound also showed anti-inflammatory activity on animal models.

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BRC0797
Product IDBRC0797
Product classBioreference compound
CAS number71125-38-7
MW351.4
Synonyms
N1539, UH-AC 62XX
Transport conditionsNormal

Meloxicam

Meloxicam is an nonsteroidal anti-inflammatory drug with analgesic and antipyretic properties. It inhibits prostaglandin synthetase (cylooxygenase 1 and 2) and leads to a decrease of the synthesis of prostaglandins, therefore, inflammation is reduced.

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BRC0842
Product IDBRC0842
Product classBioreference compound
CAS number80573-04-2
MW357.3
Synonyms
Colazide, Giazo
Transport conditionsNormal

Balsalazide

Balsalazide is a prodrug that produce mesalamine (5-aminosalicylic acid), an anti inflammatory drug.

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BRC0367
Product IDBRC0367
Product classBioreference compound
CAS number53-86-1
MW357.8
Synonyms
Indocin
Transport conditionsNormal

Indomethacin

Indomethacin, an antiinflammatory agent, inhibits Cox-1 and Cox-2 (cyclooxygenases) with selectivity for Cox-1 (IC50 of 230 nM) over Cox-2 (IC50 of 630 nM). Additionally, indomethacin displays adipogenic actions via binding and activation of PPARγ (peroxisome proliferator-activated receptor γ), a ligand-activated transcription factor known to play an important role in adipogenesis.

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BRC0542
Product IDBRC0542
Product classBioreference compound
CAS number138926-19-9
MW359.2
Synonyms
BPH 24,
Transport conditionsNormal

Ibandronate sodium monohydrate

Ibandronate is a nitrogen-containing bisphosphonate, it binds to hydroxyapatite crystals with an affinity constant of 2.36 µM, inhibiting their growth and bone resorption.

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