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Enzyme-Linked Receptors

StructureProduct infoAvailabilityQuantity / Price
BRC1048
Product IDBRC1048
Product classBioreference compound
CAS number62613-82-5
MW
Synonyms
CGP 21690; CT 848; Hydroxypiracetam; ISF 2522; Neuractiv;
Transport conditionsNormal

Oxiracetam

Oxiracetam, a cyclic derivative of gamma-aminobutyric acid (GABA), is a nootropic drug of the racetam family and very mild stimulant.

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BRC1245
Product IDBRC1245
Product classBioreference compound
CAS number98-79-3
MW129.1
Synonyms
NSC 143034; Oxoproline; Glutiminic acid; Pidolidone; Pidolic Acid;
Transport conditionsNormal

L-Pyroglutamic acid

L-Pyroglutamic acid is an amino acid that is used in the synthesis of peptides. It is cyclooxygenase inhibitor.

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BRC0622
Product IDBRC0622
Product classBioreference compound
CAS number73-24-5
MW135.1
Synonyms
Vitamin B4;
Transport conditionsNormal

Adenine

Adenine is a purine base that acts as a precursor, substrate, or cofactor in diverse biochemical pathways. It is a fundamental component of DNA, RNA, and ATP, as well as numerous other natural biochemicals.

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BRC1251
Product IDBRC1251
Product classBioreference compound
CAS number124-04-9
MW146.1
Synonyms
Acifloctin; Acinetten; Adilactetten; Adipinic acid; Asapic; E 355; Inipol DS; NSC 7622; NSC 87836;
Transport conditionsNormal

Adipic acid

Adipic acid is a dicarboxylic acid that is a useful synthetic reagent. Also, it has enzyme inhibitory activity.

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BRC1305
Product IDBRC1305
Product classBioreference compound
CAS number68252-28-8
MW158.2
Synonyms
Transport conditionsNormal

(R)-(+)-Oxiracetam

(R)-(+)-Oxiracetam is enantiomer of Oxiracetam, nootropic drug.

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BRC1041
Product IDBRC1041
Product classBioreference compound
CAS number490-91-5
MW164.2
Synonyms
NSC 2228;
Transport conditionsNormal

Thymoquinone

Thymoquinone is a natural phytochemical with anti-inflammatory effects, blocking the synthesis of leukotrienes. It inhibits the growth of leukemia cells (IC50 = 1.5 μg/ml), inducing apoptosis by down-regulating the expression of Bcl-2 while up-regulating Bax expression.

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BRC1066
Product IDBRC1066
Product classBioreference compound
CAS number498-02-2
MW166.2
Synonyms
NSC 209524; NSC 2146;
Transport conditionsNormal

Apocynin

Apocynin is a methoxy-substituted catechol that is commonly used as a selective NADPH-oxidase inhibitor with IC50 of 10 μM. Acts as an antioxidant in endothelial cells and vascular smooth muscle cells.

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BRC1044
Product IDBRC1044
Product classBioreference compound
CAS number61-80-3
MW168.6
Synonyms
Flexin; McN-485; NSC 24995; Zoxamin;
Transport conditionsNormal

Zoxazolamine

Zoxazolamine is a potent skeletal muscle relaxant that also has uricosuric activity. It is used as a tool for assessing hepatic cytochrome P-450 activity.

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BRC0133
Product IDBRC0133
Product classBioreference compound
CAS number51-43-4
MW183.2
Synonyms
Adrenalin; L-epinephrine; Levoepinephrine;
Transport conditionsNormal

Epinephrine

Epinephrine is indicated for intravenous injection in treatment of acute hypersensitivity, treatment of acute asthmatic attacks to relieve bronchospasm, and treatment and prophylaxis of cardiac arrest and attacks of transitory atrioventricular heart block with syncopal seizures (Stokes-Adams Syndrome).

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BRC0628
Product IDBRC0628
Product classBioreference compound
CAS number13721-01-2
MW189.2
Synonyms
Transport conditionsNormal

4-Quinolone-3-carboxylic acid

4-Quinolone-3-carboxylic acidis a novel HIV-1 integrase strand transfer inhibitor.

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BRC0321
Product IDBRC0321
Product classBioreference compound
CAS number4940-39-0
MW190.2
Synonyms
Atremon, Chromone-2-carboxylic acid,
Transport conditionsNormal

Chromocarb

Chromocarb is a vascular protective agent used in the treatment of venous disorders and microvascular affections.

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BRC0452
Product IDBRC0452
Product classBioreference compound
CAS number1485-00-3
MW193.2
Synonyms
NSC 10120, NSC 105303, NSC 170724, Syk Inhibitor III
Transport conditionsNormal

MNS

MNS is selective inhibitor of Src and Syk tyrosine kinases. Displays antiaggregative activity via inhibition of GPIIb/IIIa activation (IC50 = 12.7 μM for thrombin-induced platelet aggregation). Exhibits no effects on Ca2+-dependent enzymes, PKC or arachidonic acid metabolism.

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BRC0202
Product IDBRC0202
Product classBioreference compound
CAS number672-87-7
MW195.2
Synonyms
Demser, 357 O, L 588, L 588357-0, MK 781, α-MPT,
Transport conditionsNormal

Metyrosine

Metyrosine inhibits tyrosine hydroxylase, which catalyzes the first transformation in catecholamine biosynthesis, i.e., the conversion of tyrosine to dihydroxyphenylalanine (DOPA).

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BRC1319
Product IDBRC1319
Product classBioreference compound
CAS number515-13-9
MW204.4
Synonyms
Levo-β-elemene;
Transport conditionsNormal

β-Elemen

β-Elemene is a natural sesquiterpene, inhibits the proliferation of a wide range of tumors. It has antioxidant and antimicrobial properties.

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BRC0637
Product IDBRC0637
Product classBioreference compound
CAS number2809-21-4
MW206.0
Synonyms
M05BA01; NSC-227995; EHDP; HEDP; Hydroxyethylidene Diphosphonic Acid;
Transport conditionsNormal

Etidronic acid

Etidronate is a first generation, non-nitrogenous diphosphonate analog of endogenous pyrophosphate. It affects on calcium metabolism, inhibits ectopic calcification and slows down bone resorption and bone turnover.

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BRC0323
Product IDBRC0323
Product classBioreference compound
CAS number19983-44-9
MW211.2
Synonyms
STAT3 Inhibitor V
Transport conditionsNormal

Stattic

Stat3 Inhibitor V, Stattic is a small molecule shown to selectively inhibit the activation of the Stat3 transcription factor by blocking phosphorylation and dimerization events.

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BRC0609
Product IDBRC0609
Product classBioreference compound
CAS number776-53-4
MW213.3
Synonyms
Transport conditionsNormal

NSC 9310

NSC 9310 is CDK inhibitor.

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BRC0580
Product IDBRC0580
Product classBioreference compound
CAS number773-76-2
MW214.0
Synonyms
Endiaron; NSC 3904; Quesyl; CHQ;
Transport conditionsNormal

Chloroxine

Chloroxine is a synthetic antibacterial compound. It inhibits the growth of gram-positive as well as some gram-negative organisms.

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BRC0999
Product IDBRC0999
Product classBioreference compound
CAS number66-84-2
MW215.6
Synonyms
Chitosamine;
Transport conditionsNormal

Glucosamine Hydrochloride

Glucosamine is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids.

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BRC0688
Product IDBRC0688
Product classBioreference compound
CAS number1548865-41-3
MW216.6
Synonyms
Transport conditionsNormal

(2S)-2-Amino-N-2H-tetrazol-5-yl-4-pentynamide hydrochloride

The compound is cystathionine-(gamma)-lyase (CSE) inhibitor (IC50 <= 100 μM). Potential means to treat of cutaneous injuries or conditions and sleep-related breathing disorders, pain.

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BRC0300
Product IDBRC0300
Product classBioreference compound
CAS number129-56-6
MW220.2
Synonyms
Nsc75890,
Transport conditionsNormal

SP600125

SP600125 is an anthrapyrazolone inhibitor of JNK that competes with ATP to inhibit the phosphorylation of c-Jun. It prevents the activation of inflammatory genes such as COX-2, IL-2 IFN-γ and TNF-α.8,9 It prevents the activation of JNK after brain ischemia and may be effective in treatment of ischemic stroke.

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BRC1320
Product IDBRC1320
Product classBioreference compound
CAS number2482-00-0
MW228.3
Synonyms
NIH 11035; NSC 56332;
Transport conditionsNormal

Agmatine sulfate

Agmantine is a natural metabolite of the arginine. It binds to human adrenergic receptors and imidazoline (I) receptors. Agmatine acts as an antagonist of the NMDA receptor and nicotinic acetylcholine receptors. It is an antagonist of the serotonin receptor subtype 5-HT3 and blocks ATP-sensitive potassium channels. Agmatine competitively inhibits neuronal, macrophage, endothelial, and inducible nitric oxide synthase and irreversibly inactivates neuronal NOS in the presence of calmodulin.

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BRC0630
Product IDBRC0630
Product classBioreference compound
CAS number71897-07-9
MW234.3
Synonyms
AG-1295, NSC 380341
Transport conditionsNormal

Tyrphostin AG-1295

Tyrphostin AG 1295 is a cell-permeable, reversible, ATP-competitive and selective inhibitor of PDGFR (platelet-derived growth factor receptor) protein tyrosine kinase (PDGF-receptor PTK)(IC50 = 500 nM) and PDGF-dependent DNA synthesis (IC50 = 2.5 μM) in Swiss/3T3 cells, and demonstrates about 50% inhibition on neointimal formation after balloon injury in porcine femoral arteries.

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BRC0967
Product IDBRC0967
Product classBioreference compound
CAS number137-58-6
MW234.3
Synonyms
ALGRX-3268; LSM-3165; NSC-40030;
Transport conditionsNormal

Lidocaine

Lidocaine is an anaesthetic agent and class Ib antiarrhythmic agent. It is a selective inverse peripheral histamine H1-receptor agonist. This compound is known to block voltage-gated sodium channels in the inactivated state.

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BRC1421
Product IDBRC1421
Product classBioreference compound
CAS number137-26-8
MW240.4
Synonyms
Basultra; Betoxin; ENT 987; NSC 1771; NSC 49512; NSC 59637; NSC 622696; Nobecutan; SQ 1489;
Transport conditionsNormal

Thiram

Thiram is a fungicide, ectoparasiticide, and animal repellent.

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BRC0760
Product IDBRC0760
Product classBioreference compound
CAS number1018454-97-1
MW242.3
Synonyms
Transport conditionsNormal

Thienopyridone

Thienopyridone is selective phosphatase inhibitor suppresses tumor cell anchorage-independent growth by a novel mechanism involving p130Cas cleavage.

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BRC0082
Product IDBRC0082
Product classBioreference compound
CAS number51-30-9
MW247.7
Synonyms
Norisodrine, Novodrin, Isopropydrin, Aludrine
Transport conditionsNormal

Isoproterenol hydrochloride

Isoproterenol is a relatively selective beta2-adrenergic bronchodilator. Isoproterenol is indicated for the relief of bronchospasm associated with chronic obstructive pulmonary disease.

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BRC0973
Product IDBRC0973
Product classBioreference compound
CAS number66376-36-1
MW249.1
Synonyms
G 704650; GTH 4; L 670; L 670452; MK 217; ABDP;
Transport conditionsNormal

Alendronic acid

Alendronate is a second-generation bisphosphonate. Used to reduce hypercalcemia in tumor-induced bone disease, to treat corticosteroid-induced osteoporosis and Pagets disease.

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BRC0718
Product IDBRC0718
Product classBioreference compound
CAS number22071-15-4
MW254.3
Synonyms
Orudis; Oruvail;
Transport conditionsNormal

Ketoprofen

Ketoprofen is a nonsteroidal anti-inflammatory agent with analgesic and antipyretic properties. It is used to treat rheumatoid arthritis, osteoarthritis, dysmenorrhea, and alleviate moderate pain. Ketoprofen is a non-selective NSAID exhibiting IC50 values of 0.5 µM and 2.33 µM for human recombinant COX-1 and COX-2, respectively.

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BRC0121
Product IDBRC0121
Product classBioreference compound
CAS number50-35-1
MW258.2
Synonyms
Thalomid, Distaval, Softenon, Talimol,
Transport conditionsNormal
Restrictions Included in California Proposition 65 list  WARNING! This product contains a chemical known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

Thalidomide

Thalidomide is an immunomodulatory agent with a spectrum of activity that is not fully characterized. Thalidomide is racemic — it contains both left and right handed isomers in equal amounts: one enantiomer is effective against morning sickness, and the other is teratogenic.

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BRC0780
Product IDBRC0780
Product classBioreference compound
CAS number191732-72-6
MW259.3
Synonyms
CC-5013, CDC 501, IMid-1, IMiD3, ENMD 0997
Transport conditionsNormal

Lenalidomide

Lenalidomide is a thalidomide analogue. It is immunomodulatory agent possessing antiangiogenic properties.

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BRC0860
Product IDBRC0860
Product classBioreference compound
CAS number63132-39-8
MW263.1
Synonyms
Transport conditionsNormal

Olpadronic acid

Olpadronic Acid is the starting compound for obtaining bisphosphonic acid derivatives as anti-osteoporosis agents.

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BRC0915
Product IDBRC0915
Product classBioreference compound
CAS number803647-40-7
MW265.3
Synonyms
Transport conditionsNormal

NSC 59984

NSC59984 restores wild-​type p53 signaling via p73 activation, specifically in mutant p53-​expressing colorectal cancer cells. It synergizes with CPT11 to induce cell death in mutant p53-​expressing colorectal cancer cells and inhibits mutant p53-​assocd. colon tumor xenograft growth in a p73-​dependent manner in vivo.

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BRC1295
Product IDBRC1295
Product classBioreference compound
CAS number51298-62-5
MW269.7
Synonyms
Transport conditionsNormal

L-NAME hydrochloride

L-NAME hydrochloride is a nonselective inhibitor of nitric oxide synthetases.

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BRC0243
Product IDBRC0243
Product classBioreference compound
CAS number75706-12-6
MW270.2
Synonyms
Arava, HW 486, Avara, SU 101
Transport conditionsNormal

Leflunomide

Leflunomide is a pyrimidine synthesis inhibitor indicated in adults for the treatment of active rheumatoid arthritis (RA).

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BRC0817
Product IDBRC0817
Product classBioreference compound
CAS number133-16-4
MW270.8
Synonyms
Halestyn; Piocaine;
Transport conditionsNormal

Chloroprocaine

Chloroprocaine is an anesthetic agent indicated for production of local or regional anesthesia. It blocks the generation and the conduction of nerve impulses, presumably by increasing the threshold for electrical excitation in the nerve, by slowing the propagation of the nerve impulse and by reducing the rate of rising of the action potential.

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BRC0503
Product IDBRC0503
Product classBioreference compound
CAS number22816-60-0
MW271.6
Synonyms
Transport conditionsNormal

A 22 hydrochloride

A22 s a cell-permeable isothiourea compound that inhibits MreB, an actin-like bacterial protein, and has been shown to act as an antiobiotic adjuvant.

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BRC0476
Product IDBRC0476
Product classBioreference compound
CAS number315694-89-4
MW276.3
Synonyms
Transport conditionsNormal

TC-DAPK 6

TC-DAPK 6 is potent and selective, ATP-competitive inhibitor of death-associated protein kinase 1 (DAPK1) (IC50 values are 69 and 225 nM for DAPK1 and DAPK3 respectively, when assayed with 10 μM ATP). Displays selectivity for DAPK1 over a range of 48 other kinases, including Abl, AMPK, Chk1, Met and Src (IC50 > 10 μM).

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BRC0514
Product IDBRC0514
Product classBioreference compound
CAS number116970-50-4
MW287.8
Synonyms
Protein kinase inhibitor H-9
Transport conditionsNormal

H-9 hydrochloride

H-9 (hydrochloride), an isoquinolinesulfonamide protein kinase inhibitor, is a competitive inhibitor of PKC, PKG, and PKA with Ki values of 18, 0.87, and 1.9 µM, respectively.

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BRC0556
Product IDBRC0556
Product classBioreference compound
CAS number325979-58-6
MW300.4
Synonyms
Transport conditionsNormal

SB-347804

SB-347804 is a potent and selective inhibitor of JNK3 kinase (IC50 = 3.16 μM).

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BRC0303
Product IDBRC0303
Product classBioreference compound
CAS number117-39-5
MW302.2
Synonyms
Sophoretin, Meletin, Quercetol, Xanthaurine
Transport conditionsNormal

Quercetin

Quercetin is a type of plant-based chemical. In several studies, it may have anti-inflammatory and antioxidant properties, and it is being investigated for a wide range of potential health benefits. Quercetin is a PI3K inhibitor with IC50 of 2.4 – 5.4 μM.

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BRC1032
Product IDBRC1032
Product classBioreference compound
CAS number521-74-4
MW303.0
Synonyms
Fenilor; Intensopan; NSC 1810; NSC 74937;
Transport conditionsNormal

Broxyquinoline

Broxyquinoline is an antiprotozoal agent.

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BRC0545
Product IDBRC0545
Product classBioreference compound
CAS number330786-24-8
MW303.3
Synonyms
Transport conditionsNormal

3-(4-Phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine

The compound is a highly selective Bruton’s tyrosine kinase (BTK) irreversible inhibitor (IC50 < 10 µM) and useful synthetic intermediate in the synthesis of Ibrutinib.

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BRC0501
Product IDBRC0501
Product classBioreference compound
CAS number140405-36-3
MW312.4
Synonyms
Transport conditionsNormal

RSVA 405

RSVA 405 is an AMP-activated protein kinase (AMPK) activator (EC50 = 1 μM). Also inhibits LPS-induced STAT3 phosphorylation (IC50 = 0.5 μM). Induces autophagy and promotes Aβ degradation in vitro. Also inhibits adipogenesis in vitro and reduces weight gain in diet-induced obese mice.

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BRC0573
Product IDBRC0573
Product classBioreference compound
CAS number1434927-54-4
MW315.4
Synonyms
Transport conditionsNormal

C10D

C10D is novel lipoprotein lipase (LPL) agonist rescues the enzyme from inhibition by angiopoietin-like 4 (ANGPTL4).

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BRC1358
Product IDBRC1358
Product classBioreference compound
CAS number1214672-15-7
MW316.3
Synonyms
Transport conditionsNormal

LM11A-31 dihydrochloride

LM11A-31 dihydrochloride is a p75 neurotrophin receptor ligand that inhibits nerve growth factor binding to p75NTR-Fc. It inhibits DNA damage in and promotes survival of hippocampal neuronal cultures in a p75NTR- and concentration-dependent manner.

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BRC0667
Product IDBRC0667
Product classBioreference compound
CAS number125314-13-8
MW317.3
Synonyms
Transport conditionsNormal

CP21R7

CP21R7 is a potent and selective inhibitor of GSK3 beta (IC50 = 1.8 nM).

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BRC0696
Product IDBRC0696
Product classBioreference compound
CAS number332939-46-5
MW326.8
Synonyms
Transport conditionsNormal

N-[(5-Chloro-8-hydroxyquinolin-7-yl)(phenyl)methyl]acetamide

The compound is inhibitor of HIV-1 integrase-lens epithelium-derived growth factor/p75 (IN-LEDGF/p75) interaction (IC50 = 3 µM).

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BRC0083
Product IDBRC0083
Product classBioreference compound
CAS number50-65-7
MW327.1
Synonyms
Niclocide, Yomesan, Cestocid, Sagimid
Transport conditionsNormal

Niclosamide

Niclosamide is an antihelminth used against tapeworm infections. It may act by the uncoupling of the electron transport chain to ATP synthase. The disturbance of this crucial metabolic pathway prevents creation of adenosine tri-phosphate (ATP), an essential molecule that supplies energy for metabolism.

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BRC0472
Product IDBRC0472
Product classBioreference compound
CAS number380491-32-7
MW330.4
Synonyms
SJ000170251
Transport conditionsNormal

GNF-Pf-2466

GNF-Pf-2466 is kinase inhibitor. Also potential antitubercular agent (TB IC90 = 3.2).

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