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Histone Demethylase

StructureProduct infoAvailabilityQuantity / Price
BRC0341
Product IDBRC0341
Product classBioreference compound
CAS number1373423-53-0
MW417.5
Synonyms
Histone Lysine Demethylase Inhibitor VIII, GSK-J1 Pro-Drug, JMJD3 Inhibitor II
Transport conditionsNormal

GSK J4

Histone lysine demethylase (KDM) inhibitor; blocks demethylation of histone H3K27. Attenuates lipopolysaccharide (LPS)-induced proinflammatory cytokine production in primary human macrophages (IC50 = 9 μM for the inhibition of TNFα release).

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BRC0500
Product IDBRC0500
Product classBioreference compound
CAS number1287421-04-8
MW437.9
Synonyms
HCI-2509, LSD1 Inhibitor VII
Transport conditionsNormal

SP2509

SP2509 is a reversible inhibitor of LSD1 (IC50 = 13 nM) showing no activity against MAO-A, MAO-B, lactate dehydrogenase and glucose oxidase.

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