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StructureProduct infoAvailabilityQuantity / Price
BRC0177
Product IDBRC0177
Product classBioreference compound
CAS number68-41-7
MW102.1
Synonyms
DCS, Orientomycin, PA-94, Ro-1-9213, Seromycin
Transport conditionsNormal

D-Cycloserine

Cycloserine, a broad-spectrum antibiotic, may be bactericidal or bacteriostatic, depending on its concentration at the site of infection and the susceptibility of the organism. Cycloserine works by blocking the formation of these peptidoglycans. By doing this the walls of the bacteria become weak and it results in the death of the bacteria.

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BRC1354
Product IDBRC1354
Product classBioreference compound
CAS number444-27-9
MW133.2
Synonyms
Heparegene; NSC 25855; Norgamem; Detoxepa; DL-Thiaproline; ATC;
Transport conditionsNormal

Timonacic

Timonacic is shown to revert tumor cells back to normal via membrane interaction. It has been used in trials studying the treatment of HIV Infections.

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BRC0694
Product IDBRC0694
Product classBioreference compound
CAS number58-85-5
MW244.3
Synonyms
Meribin, NSC 63865, Rovimix H 2, Vitamin B7, Vitamin H
Transport conditionsNormal

Biotin

Biotin is a growth factor present in minute amounts in every living cell. Plays an indispensable role in numerous naturally occurring carboxylation reactions. Occurs mainly bound to proteins or polypeptides.

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BRC0121
Product IDBRC0121
Product classBioreference compound
CAS number50-35-1
MW258.2
Synonyms
Thalomid, Distaval, Softenon, Talimol,
Transport conditionsNormal
Restrictions Included in California Proposition 65 list  WARNING! This product contains a chemical known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

Thalidomide

Thalidomide is an immunomodulatory agent with a spectrum of activity that is not fully characterized. Thalidomide is racemic — it contains both left and right handed isomers in equal amounts: one enantiomer is effective against morning sickness, and the other is teratogenic.

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BRC0312
Product IDBRC0312
Product classBioreference compound
CAS number380315-80-0
MW369.5
Synonyms
Transport conditionsNormal

Tenovin-1

Tenovin-1 is p53 activator that protects against MDM2-mediated p53 degradation. Elevates levels of p53 and p21CIP/WAF1 and induces expression from an endogenous p53-dependent promoter. Exhibits potent antiproliferative activity in vitro.

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BRC0335
Product IDBRC0335
Product classBioreference compound
CAS number222716-34-9
MW420.5
Synonyms
Transport conditionsNormal

SZL P1-41

Skp2 inhibitor; thought to prevent assembly of Skp2-Skp1 complexes. Selectively suppresses Skp2 SCF E3 ligase activity but exhibits no effect on the activity of other SCF complexes. Also inhibits Skp2-mediated p27 and Akt ubiquitination in vivo and in vitro. Suppresses the survival of cancer cells and cancer stem cells by triggering cell senescence and inhibiting glycolysis. Exhibits antitumor effects in multiple animal models and cancer cell lines.

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BRC0442
Product IDBRC0442
Product classBioreference compound
CAS number924198-81-2
MW451.5
Synonyms
A17(SMURF1 inhibitor)
Transport conditionsNormal

A17

A17 is an inhibitor of ubiquitin ligase Smad ubiquitination regulatory factor-1 (Smuf1) that is a major regulator of bone morphogenetic protein (BMP) signaling. A17 strongly inhibits Smad1/5 ubiquitination mediated by Smuf1, increases BMP signal responsiveness and enhances BMP-2 induced osteoblastic activity.

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BRC0437
Product IDBRC0437
Product classBioreference compound
CAS number691881-87-5
MW455.9
Synonyms
Transport conditionsNormal

3-(benzo[d][1,3]dioxol-5-ylmethyl)-5-((5-(2-chlorophenyl)furan-2-yl)methylene)-2-thioxothiazolidin-4-one

Inhibitor of MDM2-mediated p53 ubiquitynation.

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BRC0016
Product IDBRC0016
Product classBioreference compound
CAS number155141-29-0
MW473.5
Synonyms
Avandia, Brl-49653, Rosiglizole, BRL49653,
Transport conditionsNormal

Rosiglitazone maleate

Rosiglitazone acts as a highly selective and potent agonist at peroxisome proliferator activated receptors (PPAR) in target tissues for insulin action such as adipose tissue, skeletal muscle, and liver. Activation of PPAR-gamma receptors regulates the transcription of insulin-responsive genes involved in the control of glucose production, transport, and utilization. In this way, rosiglitazone enhances tissue sensitivity to insulin.

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BRC0921
Product IDBRC0921
Product classBioreference compound
CAS number1007647-73-5
MW512.9
Synonyms
Transport conditionsNormal

A01 (Smurf1 inhibitor)

A01 is an inhibitor of ubiquitin ligase Smad ubiquitination regulatory factor-1 (Smuf1) that is a major regulator of bone morphogenetic protein (BMP) signaling. AO1 strongly inhibits Smad1/5 ubiquitination mediated by Smuf1, increases BMP signal responsiveness and enhances BMP-2 induced osteoblastic activity.

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