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BRC1048
Product IDBRC1048
Product classBioreference compound
CAS number62613-82-5
MW
Synonyms
CGP 21690; CT 848; Hydroxypiracetam; ISF 2522; Neuractiv;
Transport conditionsNormal

Oxiracetam

Oxiracetam, a cyclic derivative of gamma-aminobutyric acid (GABA), is a nootropic drug of the racetam family and very mild stimulant.

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BRC0168
Product IDBRC0168
Product classBioreference compound
CAS number89-57-6
MW153.1
Synonyms
5-ASA, Asacol, Asacolitin, Canasa, Claversal, Fisalamine, Iialda, Lixacol, m-Aminosalicylic acid, P-Aminosalicylsaeure, Pentasa, Rowasa, Salofalk
Transport conditionsNormal

Mesalazine

An anti-inflammatory agent, structurally related to the salicylates, which is active in inflammatory bowel disease. It is considered to be the active moiety of sulphasalazine. 

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BRC1305
Product IDBRC1305
Product classBioreference compound
CAS number68252-28-8
MW158.2
Synonyms
Transport conditionsNormal

(R)-(+)-Oxiracetam

(R)-(+)-Oxiracetam is enantiomer of Oxiracetam, nootropic drug.

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BRC0148
Product IDBRC0148
Product classBioreference compound
CAS number1115-70-4
MW165.6
Synonyms
Glucophage, Dimethylbiguanide, Glumetza, Metiguanide
Transport conditionsNormal

Metformin hydrochloride

Metformin is an oral antihyperglycemic agent that improves glucose tolerance in patients with NIDDM, lowering both basal and postprandial plasma glucose.

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BRC1104
Product IDBRC1104
Product classBioreference compound
CAS number459-86-9
MW184.2
Synonyms
NSC 32946; MGBG;
Transport conditionsNormal

Mitoguazone

Mitoguazone is a drug used in chemotherapy, in trials studying the treatment of Lymphoma, HIV Infections, and Non-Hodgkin Lymphoma.

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BRC0628
Product IDBRC0628
Product classBioreference compound
CAS number13721-01-2
MW189.2
Synonyms
Transport conditionsNormal

4-Quinolone-3-carboxylic acid

4-Quinolone-3-carboxylic acidis a novel HIV-1 integrase strand transfer inhibitor.

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BRC0150
Product IDBRC0150
Product classBioreference compound
CAS number1313437-84-1
MW209.9
Synonyms
Trilithium citrate
Transport conditionsNormal
Restrictions Included in California Proposition 65 list  WARNING! This product contains a chemical known to the State of California to cause health damage. For more information go to www.P65Warnings.ca.gov.

Lithium Citrate

Lithium salts such as lithium carbonate, lithium citrate, and lithium orotate are mood stabilizers. They are used in the treatment of bipolar disorder, since unlike most other mood altering drugs, they counteract both mania and depression.

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BRC0831
Product IDBRC0831
Product classBioreference compound
CAS number59277-89-3
MW225.2
Synonyms
NSC-645011, BW 248U
Transport conditionsNormal

Aciclovir

Aciclovir is a synthetic deoxyguanosine analog and it is the prototype antiviral agent that is activated by viral thymidine kinase.

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BRC0233
Product IDBRC0233
Product classBioreference compound
CAS number82410-32-0
MW255.2
Synonyms
GA2, Cytovene, Vitrasert, RS-21592, BW-759
Transport conditionsNormal
Restrictions Included in California Proposition 65 list  WARNING! This product contains a chemical known to the State of California to cause cancer and birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

Ganciclovir

Ganciclovir is a synthetic nucleoside analogue of 2'-deoxyguanosine that inhibits replication of herpes viruses both in vitro and in vivo. Ganciclovir is a prodrug that is structurally similar to acyclovir.

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BRC0771
Product IDBRC0771
Product classBioreference compound
CAS number95058-81-4
MW263.2
Synonyms
LY188011, NSC 613327, Zefei, DDFC
Transport conditionsNormal

Gemcitabine

Gemcitabine is an antineoplastic anti-metabolite that inhibits DNA synthesis.

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BRC0243
Product IDBRC0243
Product classBioreference compound
CAS number75706-12-6
MW270.2
Synonyms
Arava, HW 486, Avara, SU 101
Transport conditionsNormal

Leflunomide

Leflunomide is a pyrimidine synthesis inhibitor indicated in adults for the treatment of active rheumatoid arthritis (RA).

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BRC0510
Product IDBRC0510
Product classBioreference compound
CAS number327033-36-3
MW273.2
Synonyms
TCS PIM-1 4a
Transport conditionsNormal

SMI-4a

SMI-4a is a potent selective ATP-competitive Pim-1 kinase inhibitor with an IC50 of 21 nM for Pim-1 compared to an IC50 of 100 nM for Pim-2. Does not significantly inhibit any other serine/threonine- or tyrosine-kinases.

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BRC0514
Product IDBRC0514
Product classBioreference compound
CAS number116970-50-4
MW287.8
Synonyms
Protein kinase inhibitor H-9
Transport conditionsNormal

H-9 hydrochloride

H-9 (hydrochloride), an isoquinolinesulfonamide protein kinase inhibitor, is a competitive inhibitor of PKC, PKG, and PKA with Ki values of 18, 0.87, and 1.9 µM, respectively.

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BRC0302
Product IDBRC0302
Product classBioreference compound
CAS number103745-39-7
MW291.4
Synonyms
ZK-258594, HA-1077, AT-877
Transport conditionsNormal

Fasudil

Fasudil is a class of calcium antagonists. Fasudil is able to inhibit contractile responses to KCl, phenylephnne (PHE) and prostaglandin (PG) F2a. Fasudil also exhibits vasodilator actions by inhibition of 5-hydroxytryptamine, noradrenaline, histamine, angiotensin, and dopamine induced spiral strips contraction

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BRC0667
Product IDBRC0667
Product classBioreference compound
CAS number125314-13-8
MW317.3
Synonyms
Transport conditionsNormal

CP21R7

CP21R7 is a potent and selective inhibitor of GSK3 beta (IC50 = 1.8 nM).

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BRC0743
Product IDBRC0743
Product classBioreference compound
CAS number836620-48-5
MW347.4
Synonyms
Transport conditionsNormal

AS1842856

AS1842856 is cell-permeable oxodihydroquinoline that preferentially inhibits the transcription activity of Forkhead box O family member Foxo1 (IC50 = 33 nM) over that of the functionally related Foxo3a and Foxo4 (70%, 20%, and 3% inhibition, respectively, in HepG2-based reporter assays) via direct binding of the active Foxo1, but not the Ser256-phosphorylated/inactive form of Foxo1.

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BRC0558
Product IDBRC0558
Product classBioreference compound
CAS number301305-73-7
MW360.4
Synonyms
Transport conditionsNormal

TCS 359

TCS 359 is a potent inhibitor of FLT3 receptor tyrosine kinase (IC50 = 42 nM) that displays selectivity over a range of other kinases.

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BRC0398
Product IDBRC0398
Product classBioreference compound
CAS number124832-27-5
MW360.8
Synonyms
Bagovir, Cycloval,Mitanga, Ovalac, Pervioral, Revira, Vacyless, Vadiral, Valdacir, Valotix, Valtrex, Valvir, Valztrex, Viramixal, Viropel, Vociflon, Zelitrex, Zelivire
Transport conditionsNormal

Valaciclovir hydrochloride

Valaciclovir (INN) or Valacyclovir (USAN) is a prodrug and synthetic purine nucleoside analogue with inhibitory activity against herpes simplex virus types 1 (HSV-1), 2 (HSV-2), varicella-zoster virus (VZV), Epstein-Barr virus (EBV), and cytomegalovirus (CMV).

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BRC0349
Product IDBRC0349
Product classBioreference compound
CAS number75607-67-9
MW365.2
Synonyms
F-ara-A (NSC 312887) Phosphate, NSC-118218
Transport conditionsNormal

Fludarabine phosphate

Fludarabine is a chemotherapy drug used in the treatment of chronic lymphocytic leukemia. It acts at DNA polymerase alpha, ribonucleotide reductase and DNA primase, results in the inhibition of DNA synthesis, and destroys the cancer cells.

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BRC0064
Product IDBRC0064
Product classBioreference compound
CAS number10540-29-1
MW371.5
Synonyms
Zemide, Ethanamine, ICI 46474
Transport conditionsNormal
Restrictions Included in California Proposition 65 list  WARNING! This product contains a chemical known to the State of California to cause cancer. For more information go to www.P65Warnings.ca.gov.

Tamoxifen

Tamoxifen is indicated for the treatment of metastatic breast cancer in women and men and ductal carcinoma in Situ. Tamoxifen is a nonsteroidal agent that binds to estrogen receptors (ER), inducing a conformational change in the receptor. This results in a blockage or change in the expression of estrogen dependent genes. The prolonged binding of tamoxifen to the nuclear chromatin of these results in reduced DNA polymerase activity, impaired thymidine utilization, blockade of estradiol uptake, and decreased estrogen response.

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BRC0680
Product IDBRC0680
Product classBioreference compound
CAS number169590-42-5
MW381.4
Synonyms
Eurocox, Medicoxib, SC 58635, Xilebao, YM 177
Transport conditionsNormal

Celecoxib

Celecoxib is a selective cyclooxygenase-2 (Cox-2) inhibitor (IC50 = 40 nM) with low sensitivity against Cox-1. Celecoxib is a non-steroidal anti-inflammatory drug (NSAID) used in the treatment of osteoarthritis, rheumatoid arthritis, acute pain, painful menstruation and menstrual symptoms.

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BRC0635
Product IDBRC0635
Product classBioreference compound
CAS number256477-09-5
MW385.8
Synonyms
Transport conditionsNormal

UK-371804

UK-371804 is a potent and selective inhibitor of urokinase-type plasmogen activator (uPA) (Ki=10 nM). Selectivity is 4000-fold versus tPA and 2700-fold versus plasmin.

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BRC0531
Product IDBRC0531
Product classBioreference compound
CAS number1209784-87-1
MW389.5
Synonyms
Transport conditionsNormal

2-[[[2-(4-Ethoxy-3-methoxyphenyl)-4-thiazolyl]methyl]thio]-4,6-pyrimidinediamine

The compound is deoxycytidine kinase inhibitor (IC50 = 1.12 μM).

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BRC0702
Product IDBRC0702
Product classBioreference compound
CAS number599-79-1
MW398.4
Synonyms
NSC 203730, NSC 667219, Reupirin, Azulfin, Benzosulfa
Transport conditionsNormal
Restrictions Included in California Proposition 65 list  WARNING! This product contains a chemical known to the State of California to cause cancer and birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

Sulfasalazine

Sulfasalazine is an anti-inflammatory (gastrointestinal). It is inhibitor of NF-κB activation. Inhibits in vitro growth of the human pancreatic cancer cell lines MIA PaCa-2 and PANC-1, and induces apoptosis in glioblastoma cell lines. Also inhibits the cystine-glutamate antiporter, system Xc (SXC).

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BRC0502
Product IDBRC0502
Product classBioreference compound
CAS number2060523-50-2
MW409.7
Synonyms
Transport conditionsNormal

4-(aminomethyl)-N'-(5-bromo-2-oxo-2,3-dihydro-1H-indol-3-ylidene)benzohydrazide hydrochloride

Is an inhibitor of human recombinant PKR autophosphorylation.

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BRC0577
Product IDBRC0577
Product classBioreference compound
CAS number1809862-74-5
MW424.5
Synonyms
Transport conditionsNormal

3-methyloxetan-3-yl 4-[3-(2-methoxypyridin-3-yl)pyrazolo[1,5-a]pyrimidin-5-yl]piperazine-1-carboxylate

The compound is potent, brain penetrant inhibitor of AP2-associated protein kinase 1 (IC50 = 4.7 nM).

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BRC0331
Product IDBRC0331
Product classBioreference compound
CAS number183319-69-9
MW429.9
Synonyms
CP358774, NSC 718781
Transport conditionsNormal

Erlotinib hydrochloride

Erlotinib inhibits the intracellular phosphorylation of tyrosine kinase associated with the epidermal growth factor receptor (EGFR).

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BRC0376
Product IDBRC0376
Product classBioreference compound
CAS number1042432-58-5
MW438.9
Synonyms
Transport conditionsNormal

CTx-0152960

CTx-0152960, was reported as a new member of the broad spectrum PKI family and developed as a Sepharose-supported kinase capture reagent in the identification of 235 protein kinases from a digest of human breast adenocarcinoma, MDA-MB-231, cells.

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BRC0592
Product IDBRC0592
Product classBioreference compound
CAS number1448694-02-7
MW447.5
Synonyms
Transport conditionsNormal

GCN2-IN-3

GCN2-IN-3 is inhibitor of GCN2 (IC50 < 0.3 µM).

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BRC0723
Product IDBRC0723
Product classBioreference compound
CAS number1589527-65-0
MW518.5
Synonyms
Transport conditionsNormal

KIRA 6

KIRA 6 is an allosteric inhibitor of IRE1α RNase, preserves cell viability and function in ER-stressed retinitis pigmentosa and diabetes model cells.

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BRC0332
Product IDBRC0332
Product classBioreference compound
CAS number388082-78-8
MW581.1
Synonyms
FMM, GW 572016, Tykerb
Transport conditionsNormal

Lapatinib ditosylate

Lapatinib is a 4-anilinoquinazoline kinase inhibitor of the intracellular tyrosine kinase domains of both epidermal growth factor receptor (HER1/EGFR/ERBB1) and human epidermal growth factor receptor type 2 (HER2/ERBB2)with a dissociation half-life of ≥300 minutes. Lapatinib inhibits ERBB-driven tumor cell growth in vitro and in various animal models.

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BRC0255
Product IDBRC0255
Product classBioreference compound
CAS number34031-32-8
MW678.5
Synonyms
Ridaura, Triethylphosphine gold
Transport conditionsNormal
Restrictions Included in California Proposition 65 list  WARNING! This product contains a chemical known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

Auranofin

Auranofin is a gold salt used in treating inflammatory arthritis. It may act as an inhibitor of kappab kinase and thioredoxin reductase which would lead to a decreased immune response and decreased free radical production, respectively.

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