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Cyclin-dependent protein kinases (CDK)

StructureProduct infoAvailabilityQuantity / Price
BRC0452
Product IDBRC0452
Product classBioreference compound
CAS number1485-00-3
MW193.2
Synonyms
NSC 10120, NSC 105303, NSC 170724, Syk Inhibitor III
Transport conditionsNormal

MNS

MNS is selective inhibitor of Src and Syk tyrosine kinases. Displays antiaggregative activity via inhibition of GPIIb/IIIa activation (IC50 = 12.7 μM for thrombin-induced platelet aggregation). Exhibits no effects on Ca2+-dependent enzymes, PKC or arachidonic acid metabolism.

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BRC0609
Product IDBRC0609
Product classBioreference compound
CAS number776-53-4
MW213.3
Synonyms
Transport conditionsNormal

NSC 9310

NSC 9310 is CDK inhibitor.

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BRC0877
Product IDBRC0877
Product classBioreference compound
CAS number2447-23-6
MW229.1
Synonyms
Transport conditionsNormal

SNX9-1

SNX9-1 is a CDK inhibitor.

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BRC0838
Product IDBRC0838
Product classBioreference compound
CAS number56296-78-7
MW345.8
Synonyms
Lilly 103472; Lilly 110 140; Prozac;
Transport conditionsNormal

Fluoxetine Hydrochloride

Fluoxetine hydrochloride is the first-in-class antidepressant, selective serotonin-reuptake inhibitor. It displays a selectivity for the serotonin transporter (Kd = 0.81 nM) over the norepinephrine transporter (Kd = 240 nM) and the dopamine transporter (Kd = 3,600 nM). It is used in the clinical treatment of major depression as well as other psychiatric disorders.

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BRC0793
Product IDBRC0793
Product classBioreference compound
CAS number710323-58-3
MW356.2
Synonyms
GSK 3 Inhibitor IX; MLS 2052; 6-Bromoindirubin-3-oxime;
Transport conditionsNormal

BIO

BIO is a cell-permeable, highly potent, selective, reversible and ATP-competitive glycogen synthase kinase-3 inhibitor. Maintains self-renewal and pluripotency in embryonic stem cells via activation of the Wnt signaling pathway in vitro. Also, promotes proliferation and dedifferentiation in cardiomyocytes.

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BRC0790
Product IDBRC0790
Product classBioreference compound
CAS number313967-18-9
MW438.5
Synonyms
Transport conditionsNormal

FLI-06

FLI-06 is a novel inhibitor of Notch signaling (EC50 = 2.3 μM). It disrupts Notch trafficking and processing, reduces amyloid β secretion, changes the maturation and abolishes shredding of APP, inhibits ER exporting and converts tubular ER to sheets.

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BRC0707
Product IDBRC0707
Product classBioreference compound
CAS number1394011-91-6
MW481.8
Synonyms
Transport conditionsNormal

UC 2288

UC 2288 is novel p21 attenuator which is structurally related to sorafenib. Soluble epoxide hydrolase inhibitor (IC50 = 2.9 nM).

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BRC0581
Product IDBRC0581
Product classBioreference compound
CAS number129453-61-8
MW606.8
Synonyms
ICI 182780, ZD 182780, ZD 9238
Transport conditionsNormal

Fulvestrant

Fulvestrant is an estrogen receptor antagonist (IC50 = 0.29 nM) with no agonist effects, which works both by down-regulating and by degrading the estrogen receptor.

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