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Src kinases

StructureProduct infoAvailabilityQuantity / Price
BRC0452
Product IDBRC0452
Product classBioreference compound
CAS number1485-00-3
MW193.2
Synonyms
NSC 10120, NSC 105303, NSC 170724, Syk Inhibitor III
Transport conditionsNormal

MNS

MNS is selective inhibitor of Src and Syk tyrosine kinases. Displays antiaggregative activity via inhibition of GPIIb/IIIa activation (IC50 = 12.7 μM for thrombin-induced platelet aggregation). Exhibits no effects on Ca2+-dependent enzymes, PKC or arachidonic acid metabolism.

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BRC0793
Product IDBRC0793
Product classBioreference compound
CAS number710323-58-3
MW356.2
Synonyms
GSK 3 Inhibitor IX; MLS 2052; 6-Bromoindirubin-3-oxime;
Transport conditionsNormal

BIO

BIO is a cell-permeable, highly potent, selective, reversible and ATP-competitive glycogen synthase kinase-3 inhibitor. Maintains self-renewal and pluripotency in embryonic stem cells via activation of the Wnt signaling pathway in vitro. Also, promotes proliferation and dedifferentiation in cardiomyocytes.

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BRC0330
Product IDBRC0330
Product classBioreference compound
CAS number302962-49-8
MW488.0
Synonyms
BMS 354825, Sprycel
Transport conditionsNormal

Dasatinib

Dasatinib is an oral dual BCR/ABL and Src family tyrosine kinase inhibitor approved for use in patients with chronic myelogenous leukemia (CML). The main targets of Dasatinib, are BCRABL, SRC, Ephrins and GFR.

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