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RAF kinases

StructureProduct infoAvailabilityQuantity / Price
BRC0503
Product IDBRC0503
Product classBioreference compound
CAS number22816-60-0
MW271.6
Synonyms
Transport conditionsNormal

A 22 hydrochloride

A22 s a cell-permeable isothiourea compound that inhibits MreB, an actin-like bacterial protein, and has been shown to act as an antiobiotic adjuvant.

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BRC0553
Product IDBRC0553
Product classBioreference compound
CAS number1400989-38-9
MW453.4
Synonyms
Transport conditionsNormal

N-[3-(3-Amino-4-nitrophenoxy)phenyl]-3-(trifluoromethyl)benzenesulfonamide

The compound is protein tyrosine phosphatase SHP1 agonist.

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BRC0219
Product IDBRC0219
Product classBioreference compound
CAS number284461-73-0
MW464.8
Synonyms
BAY 43-9006, Nexavar,
Transport conditionsNormal

Sorafenib

Sorafenib is a small molecular inhibitor of Raf kinase, PDGF (platelet-derived growth factor), VEGF receptor 2 and 3 kinases and c Kit the receptor for Stem cell factor. A growing number of drugs target most of these pathways. The originality of Sorafenib lays in its simultaneous targeting of the Raf/Mek/Erk pathway.

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BRC0707
Product IDBRC0707
Product classBioreference compound
CAS number1394011-91-6
MW481.8
Synonyms
Transport conditionsNormal

UC 2288

UC 2288 is novel p21 attenuator which is structurally related to sorafenib. Soluble epoxide hydrolase inhibitor (IC50 = 2.9 nM).

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