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Phosphatidylinositol 3-kinase (PDK)

StructureProduct infoAvailabilityQuantity / Price
BRC0295
Product IDBRC0295
Product classBioreference compound
CAS number58-08-2
MW194.2
Synonyms
Methyltheobromine, NSC 5036
Transport conditionsNormal

Caffeine

Central nervous system stimulant. Antagonist at A1 and A2A adenosine receptors and inhibitor of cyclic nucleotide phosphodiesterases. Mobilizes calcium from intracellular stores and inhibits benzodiazepine binding to GABA receptors.

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BRC0082
Product IDBRC0082
Product classBioreference compound
CAS number51-30-9
MW247.7
Synonyms
Norisodrine, Novodrin, Isopropydrin, Aludrine
Transport conditionsNormal

Isoproterenol hydrochloride

Isoproterenol is a relatively selective beta2-adrenergic bronchodilator. Isoproterenol is indicated for the relief of bronchospasm associated with chronic obstructive pulmonary disease.

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BRC0303
Product IDBRC0303
Product classBioreference compound
CAS number117-39-5
MW302.2
Synonyms
Sophoretin, Meletin, Quercetol, Xanthaurine
Transport conditionsNormal

Quercetin

Quercetin is a type of plant-based chemical. In several studies, it may have anti-inflammatory and antioxidant properties, and it is being investigated for a wide range of potential health benefits. Quercetin is a PI3K inhibitor with IC50 of 2.4 – 5.4 μM.

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BRC0545
Product IDBRC0545
Product classBioreference compound
CAS number330786-24-8
MW303.3
Synonyms
Transport conditionsNormal

3-(4-Phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine

The compound is a highly selective Bruton’s tyrosine kinase (BTK) irreversible inhibitor (IC50 < 10 µM) and useful synthetic intermediate in the synthesis of Ibrutinib.

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BRC0433
Product IDBRC0433
Product classBioreference compound
CAS number154447-36-6
MW307.3
Synonyms
NSC 697286, SF 1101, LY 294002
Transport conditionsNormal

LY294002

LY294002 is a potent inhibitor of numerous proteins, and a strong inhibitor of phosphoinositide 3-kinases (PI3Ks).

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BRC0720
Product IDBRC0720
Product classBioreference compound
CAS number1276110-06-5
MW422.5
Synonyms
Transport conditionsNormal

HS 173

HS-173 is a potent PI3Kα inhibitor (IC50 = 0.8 nM) with anticancer activity.

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