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BRC1419
Product IDBRC1419
Product classBioreference compound
CAS number107-97-1
MW89.1
Synonyms
Methylglycine; N-Methylaminoacetic acid; Sarcosin; Sarcosinic acid;
Transport conditionsNormal

Sarcosine

Sarcosine is an endogenous inhibitor of GlyT1 with antipsychotic activity. It potentiates the action of glycine on the NMDA glycine binding site.

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BRC1413
Product IDBRC1413
Product classBioreference compound
CAS number77-75-8
MW98.1
Synonyms
NSC 28797; NSC 975; Oblivon; Somnesin; Dormison;
Transport conditionsNormal

Meparfylon

Meparfylon is MAO inhibitor, an antidepressant.

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BRC0928
Product IDBRC0928
Product classBioreference compound
CAS number68506-86-5
MW129.2
Synonyms
CPP-109; MDL 71,754; MDL-71754; RMI-71754; GVG; Sabril™; γ-Vinyl GABA;
Transport conditionsNormal

Vigabatrin

Vigabatrin is a structural analogue of gamma-aminobutyric acid, irreversible inhibitor of 4-aminobutyrate transaminase, the enzyme responsible for the catabolism of gamma-aminobutyric acid.

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BRC0982
Product IDBRC0982
Product classBioreference compound
CAS number5638-76-6
MW136.2
Synonyms
Transport conditionsNormal

Betahistine

Betahistine is an antivertigo drug, a histamine analog, and H1 receptor agonist. It serves as a vasodilator and is most commonly used to treat the symptoms of vertigo. Betahistine also has a strong affinity as an antagonist for histamine H3 receptors.

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BRC0993
Product IDBRC0993
Product classBioreference compound
CAS number65-45-2
MW137.1
Synonyms
OHB;
Transport conditionsNormal

Salicylamide

Salicylamide is an analgesic and antipyretic agent. Its medicinal uses are similar to those of aspirin.

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BRC0859
Product IDBRC0859
Product classBioreference compound
CAS number69-72-7
MW138.1
Synonyms
FEMA NO. 3985; K-557; NSC-180;
Transport conditionsNormal

Salicylic acid

Salicylic acid is bacteriostatic, fungicide and keratolytic agent. It is directly and irreversibly inhibits the activity of COX-1 and COX-2 to decrease the formation of precursors of prostaglandins and thromboxanes from arachidonic acid.

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BRC0873
Product IDBRC0873
Product classBioreference compound
CAS number67-48-1
MW139.6
Synonyms
Bilineurine;
Transport conditionsNormal

Choline

Choline is a precursor to acetylcholine. It is needed for good nerve conduction throughout the CNS. Choline is also needed for gallbladder regulation, liver function, and lecithin formation; for cholesterol metabolism and prevents excessive fat build up in the liver.

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BRC0939
Product IDBRC0939
Product classBioreference compound
CAS number77-67-8
MW141.2
Synonyms
H 940; Mesentol; NSC 64013; PM 671; CN 10395;
Transport conditionsNormal

Ethosuximide

Ethosuximide is an anticonvulsant, used in the treatment of epilepsy. It binds to T-type voltage-sensitive calcium channels.

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BRC0977
Product IDBRC0977
Product classBioreference compound
CAS number7491-74-9
MW142.2
Synonyms
UCB 6215;
Transport conditionsNormal

Piracetam

Piracetam is a nootropic drug that displays cognitive enhancing properties. It is a cyclic derivative of GABA. It has been shown to alter the physical properties of cell membranes and to protect against hypoxia, which might underlie neuroprotective and antithrombotic actions.

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BRC0288
Product IDBRC0288
Product classBioreference compound
CAS number127-48-0
MW143.1
Synonyms
Trimethinum, Troxidone, Tridione, Minoale,
Transport conditionsNormal
Restrictions Included in California Proposition 65 list  WARNING! This product contains a chemical known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

Trimethadione

Trimethadione is an oxazolidinedione anticonvulsant. It is most commonly used to treat epileptic conditions that are resistant to other treatments.

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BRC0249
Product IDBRC0249
Product classBioreference compound
CAS number99-66-1
MW144.2
Synonyms
DPA, n-DPA, Valproate, VPA, Convulex, Depakine, Encorate, Epilim, Valcote, Valparin
Transport conditionsNormal
Restrictions Included in California Proposition 65 list  WARNING! This product contains a chemical known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

Valproic Acid

Valproic acid is a fatty acid with anticonvulsant properties used in the treatment of epilepsy.

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BRC0981
Product IDBRC0981
Product classBioreference compound
CAS number103-90-2
MW151.2
Synonyms
NSC-109028; NSC-3991; APAP; Acenol; Paracetamol;
Transport conditionsNormal

Acetaminophen

Acetaminophen is a widely used analgesic and antipyretic drug that is used for the relief of fever, headaches, and other minor aches and pains. It is thought to act primarily in the CNS, increasing the pain threshold by inhibiting both isoforms of cyclooxygenase, COX-1, COX-2, and COX-3 enzymes involved in prostaglandin synthesis.

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BRC1033
Product IDBRC1033
Product classBioreference compound
CAS number64-65-3
MW155.2
Synonyms
Mikedimide; NP 13; NSC 168667; NSC 58187; Zentraleptin;
Transport conditionsNormal

Bemegride

Bemegride is a central nervous system stimulant and antidote for barbiturate poisoning as its chemoreceptor agonism increases mean tidal volume, thereby increasing respiration and the concentration of O2 in blood.

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BRC0878
Product IDBRC0878
Product classBioreference compound
CAS number54-11-5
MW162.2
Synonyms
Transport conditionsNormal
Restrictions Included in California Proposition 65 list  WARNING! This product contains a chemical known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

Nicotine

Nicotine is highly toxic alkaloid, nicotinic acetylcholine receptors agonist. In the brain, nicotine binds to nicotinic acetylcholine receptors on dopaminergic neurons in the cortico-limbic pathways. It exhibits vasoconstrictive, hypertensive and prothrombotic activity.

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BRC0692
Product IDBRC0692
Product classBioreference compound
CAS number76-38-0
MW165.0
Synonyms
DA-759; NSC-110432;
Transport conditionsNormal

Methoxyflurane

Methoxyflurane is an anesthetic used for induction and maintenance of general anesthesia. It induces muscle relaxation and reduces pains sensitivity by altering tissue excitability.

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BRC0966
Product IDBRC0966
Product classBioreference compound
CAS number94-09-7
MW165.2
Synonyms
AR01; NSC-41531; NSC-4688;
Transport conditionsNormal

Benzocaine

Benzocaine is a local anesthetic commonly used as a topical pain reliever. It binds to sodium channels and reversibly stabilizes the neuronal membrane which decreases its permeability to sodium ions.

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BRC1066
Product IDBRC1066
Product classBioreference compound
CAS number498-02-2
MW166.2
Synonyms
NSC 209524; NSC 2146;
Transport conditionsNormal

Apocynin

Apocynin is a methoxy-substituted catechol that is commonly used as a selective NADPH-oxidase inhibitor with IC50 of 10 μM. Acts as an antioxidant in endothelial cells and vascular smooth muscle cells.

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BRC0213
Product IDBRC0213
Product classBioreference compound
CAS number95-25-0
MW169.6
Synonyms
Myoflexin, Paraflex, Relaxazone, Remular, Remular-S, Solaxin, Strifon Forte DSC
Transport conditionsNormal

Chlorzoxazone

A centrally acting central muscle relaxant with sedative properties. It is claimed to inhibit muscle spasm by exerting an effect primarily at the level of the spinal cord and subcortical areas of the brain.

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BRC0020
Product IDBRC0020
Product classBioreference compound
CAS number1986-47-6
MW169.6
Synonyms
Parnate; Transamine; Jatrosom;
Transport conditionsNormal

(1R,2S)-(+)-Tranylcypromine hydrochloride

Tranylcypromine hydrochloride is a non-hydrazine monoamine oxidase inhibitor with a rapid onset of activity.

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BRC0274
Product IDBRC0274
Product classBioreference compound
CAS number102767-28-2
MW170.2
Synonyms
UCB 22059, UCB L059, UCB-22059, UCB-L059, SIB-S1, Keppra
Transport conditionsNormal

Levetiracetam

Levetiracetam is an anticonvulsant medication used to treat epilepsy. Levetiracetam may selectively prevent hypersynchronization of epileptiform burst firing and propagation of seizure activity.

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BRC1056
Product IDBRC1056
Product classBioreference compound
CAS number51-15-0
MW172.6
Synonyms
Protopam chloride; 2-PAM chloride; NSC 164614; UNII-P7MU9UTP52;
Transport conditionsNormal

Pralidoxime chloride

Pralidoxime is an antidote to organophosphate pesticides and chemicals. It binds to inactivated acetylcholinesterases.

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BRC0615
Product IDBRC0615
Product classBioreference compound
CAS number2078-54-8
MW178.3
Synonyms
ICI 35868; Disoprivan; Disoprofol;
Transport conditionsNormal

Propofol

Propofol is a sedative-hypnotic agent for use in the induction and maintenance of anesthesia or sedation. It acts as a potentiator of the GABAA receptor.

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BRC0319
Product IDBRC0319
Product classBioreference compound
CAS number62-44-2
MW179.2
Synonyms
Achrocidin, Codempiral, Commotional, Contradol, Contradouleur
Transport conditionsNormal
Restrictions Included in California Proposition 65 list  WARNING! This product contains a chemical known to the State of California to cause cancer. For more information go to www.P65Warnings.ca.gov.

Phenacetin

Phenacetin was the first NSAID and fever reducer to go on the market. Its analgesic effects are due to its actions on the sensory tracts of the spinal cord. In addition, phenacetin has a depressant action of the heart, where it acts as a negative inotrope.

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BRC0251
Product IDBRC0251
Product classBioreference compound
CAS number75448-53-2
MW180.2
Synonyms
Elixophyllin, Respbid, Theo-dur, Theolair, Uniphyl
Transport conditionsNormal

Theophylline

Theophylline, an xanthine derivative chemically similar to caffeine and theobromine, is used to treat asthma and bronchospasm. Theophylline has two distinct actions in the airways of patients with reversible (asthmatic) obstruction; smooth muscle relaxation (i.e., bronchodilation) and suppression of the response of the airways to stimuli (i.e., non-bronchodilator prophylactic effects).

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BRC1007
Product IDBRC1007
Product classBioreference compound
CAS number146255-66-5
MW183.2
Synonyms
(RS)-3,5-Dihydroxyphenylglycine;
Transport conditionsNormal

DHPG

DHPG is an agonist of the group I metabotropic glutamate receptors, binding both mGluR1a and mGluR5a (Ki = 0.9 and 3.9 µM, respectively) but not ionotropic glutamate receptors. The (S)-enantiomer is about ten times more potent than the (R)-enantiomer.

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BRC0633
Product IDBRC0633
Product classBioreference compound
CAS number56-92-8
MW184.1
Synonyms
NSC-257873; NSC-33792;
Transport conditionsNormal

Histamine Dihydrochloride

Histamine is a depressor amine. It is a powerful stimulant of gastric secretion, a bronchoconstrictor, vasodilator, and also a centrally acting neurotransmitter.

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BRC0956
Product IDBRC0956
Product classBioreference compound
CAS number138-92-1
MW184.1
Synonyms
Ametazole;
Transport conditionsNormal

Betazole Dihydrochloride

Betazole dihydrochloride is a histamine H2 agonist used in a test for measuring maximal production of gastric acidity or anacidity.

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BRC0687
Product IDBRC0687
Product classBioreference compound
CAS number13838-16-9
MW184.5
Synonyms
Anesthetic 347; Alyrane;
Transport conditionsNormal

Enflurane

Enflurane is an anesthetic. It induces muscle relaxation and reduces pains sensitivity by altering tissue excitability. Enflurane acts as a positive allosteric modulator of the GABAA, glycine, and 5-HT3 receptors, and as a negative allosteric modulator of the AMPA, kainate, and NMDA receptors, as well as of nicotinic acetylcholine receptors.

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BRC0260
Product IDBRC0260
Product classBioreference compound
CAS number665-66-7
MW187.7
Synonyms
Aminoadamantane, Viregyt, Virosol, PK-Merz, Symadine, Symmetrel
Transport conditionsNormal
Restrictions Included in California Proposition 65 list  WARNING! This product contains a chemical known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

Amantadine hydrochloride

Amantadine is an antiviral drug which also acts as an antiparkinson agent, for which it is usually combined with L-DOPA when L-DOPA responses decline (probably due to tolerance).

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BRC0978
Product IDBRC0978
Product classBioreference compound
CAS number60-80-0
MW188.2
Synonyms
Transport conditionsNormal

Antipyrine

Antipyrine is an analgesic and antipyretic. It inhibits isoforms of cyclooxygenase, COX-1, COX-2, and COX-3 enzymes involved in prostaglandin (PG) synthesis. Antipyrine is often used in testing the effects of other drugs or diseases on drug-metabolizing enzymes in the liver.

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BRC0023
Product IDBRC0023
Product classBioreference compound
CAS number62-31-7
MW189.6
Synonyms
3-Hydroxytyramine, Deoxyepinephrine, Oxytyramine, Intropin, Revimine
Transport conditionsNormal

Dopamine hydrochloride

Dopamine is a natural catecholamine formed by the decarboxylation of 3,4-dihydroxyphenylalanine (DOPA). It is a precursor to norepinephrine in noradrenergic nerves and is also a neurotransmitter in certain areas of the central nervous system, especially in the nigrostriatal tract, and in a few peripheral sympathetic nerves. Dopamine produces positive chronotropic and inotropic effects on the myocardium, resulting in increased heart rate and cardiac contractility.

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BRC1080
Product IDBRC1080
Product classBioreference compound
CAS number94-25-7
MW193.2
Synonyms
Butylcaine; Hemoride; NSC 128464; Planoform; Scuroform;
Transport conditionsNormal

Butamben

Butamben is a mildly water-soluble, long-duration local anesthetic that is thought to reversibly blocking nerve conduction.

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BRC0719
Product IDBRC0719
Product classBioreference compound
CAS number41078-02-8
MW194.2
Synonyms
3-Propylxanthine, D 4028
Transport conditionsNormal

Enprofylline

Enprofylline is a synthetic dimethylxanthine derivative, it antagonizes erythrocyte phosphodiesterase, increasing cAMP activity.

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BRC0295
Product IDBRC0295
Product classBioreference compound
CAS number58-08-2
MW194.2
Synonyms
Methyltheobromine, NSC 5036
Transport conditionsNormal

Caffeine

Central nervous system stimulant. Antagonist at A1 and A2A adenosine receptors and inhibitor of cyclic nucleotide phosphodiesterases. Mobilizes calcium from intracellular stores and inhibits benzodiazepine binding to GABA receptors.

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BRC0840
Product IDBRC0840
Product classBioreference compound
CAS number59-92-7
MW197.2
Synonyms
V-1512; Pardopa; Syndopa; L-dopa;
Transport conditionsNormal
Restrictions Included in California Proposition 65 list  WARNING! This product contains a chemical known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

Levodopa

Levodopa is a metabolic precursor of dopamine that is capable of crossing the blood-brain barrier. It is used to replace dopamine lost in Parkinsons disease.

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BRC1074
Product IDBRC1074
Product classBioreference compound
CAS number153322-05-5
MW198.3
Synonyms
ARL 15896; FPL 15896; AR-R15896; AZD6765;
Transport conditionsNormal

Lanicemine

Lanicemine is a non-selective, voltage-dependent NMDA channel blocker (IC50 = 4-7 µM). It has been used in trials studying the treatment and basic science of Depression, Major Depressive Disorder, and Treatment-Resistant Major Depressive Disorder.

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BRC0390
Product IDBRC0390
Product classBioreference compound
CAS number55-65-2
MW198.3
Synonyms
Ismedine, Ismelin
Transport conditionsNormal

Guanethidine

Guanethidine works by decreasing the heart rate and relaxing the blood vessels so that blood can flow more easily through the body, thereby reducing these risks. It is a postganglionic sympathetic nerve terminal blocker that prevents the release of norepinephrine from nerve terminals.

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BRC1030
Product IDBRC1030
Product classBioreference compound
CAS number92-84-2
MW199.3
Synonyms
Fenoverm; NSC 2037; Dibenzothiazine; ENT 38;
Transport conditionsNormal

Phenothiazine

Phenothiazine is a rigid, tricyclic thiazine useful as an electron donor. It was formerly used as an insecticide and as a drug to treat infections with parasitic worms (anthelminthic).

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BRC0857
Product IDBRC0857
Product classBioreference compound
CAS number28523-86-6
MW200.1
Synonyms
Transport conditionsNormal

Sevoflurane

Sevoflurane is one of the most commonly used volatile anesthetic agents, particularly for outpatient anesthesia, across all ages, as well as in veterinary medicine.

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BRC0098
Product IDBRC0098
Product classBioreference compound
CAS number826-39-1
MW203.8
Synonyms
Inversine; Versamine;
Transport conditionsNormal

Mecamylamine hydrochloride

Mecamylamine hydrochloride is a potent, oral antihypertensive agent and ganglion blocker.

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BRC1178
Product IDBRC1178
Product classBioreference compound
CAS number209185-99-9
MW205.8
Synonyms
Transport conditionsNormal

Neramexane hydrochloride

Neramexane hydrochloride is an NMDA antagonist with neuroprotective effects. It targets the cognitive decline in Alzheimer’s Disease by altering neurotransmitter signaling. Neramexane also acts as a nicotinic acetylcholine receptor antagonist.

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BRC0827
Product IDBRC0827
Product classBioreference compound
CAS number51146-56-6
MW206.3
Synonyms
d-ibuproten; S(+)-ibuprofen;
Transport conditionsNormal

Dexibuprofen

Dexibuprofen is a non-steroidal anti-inflammatory drug. It is a pharmacologically effective enantiomer of racemic ibuprofen that differs in physicochemical properties.

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BRC0814
Product IDBRC0814
Product classBioreference compound
CAS number15687-27-1
MW206.3
Synonyms
NSC 256857; U-18753;
Transport conditionsNormal

Ibuprofen

Ibuprofen is a nonsteroidal anti-inflammatory agent with analgesic and antipyretic properties. It is a non-selective, reversible COX inhibitor (IC50 for human recombinant COX-1 and COX-2 are 2.6 and 1.53 µM, respectively).

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BRC0955
Product IDBRC0955
Product classBioreference compound
CAS number16904-30-6
MW209.1
Synonyms
W 1544;
Transport conditionsNormal

Phenelzine Dihydrochloride

Phenelzine dihydrochloride is an antidepressant, irreversible non-selective monoamine oxidase inhibitor. May be used to treat major depressive disorder.

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BRC0150
Product IDBRC0150
Product classBioreference compound
CAS number1313437-84-1
MW209.9
Synonyms
Trilithium citrate
Transport conditionsNormal
Restrictions Included in California Proposition 65 list  WARNING! This product contains a chemical known to the State of California to cause health damage. For more information go to www.P65Warnings.ca.gov.

Lithium Citrate

Lithium salts such as lithium carbonate, lithium citrate, and lithium orotate are mood stabilizers. They are used in the treatment of bipolar disorder, since unlike most other mood altering drugs, they counteract both mania and depression.

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BRC0972
Product IDBRC0972
Product classBioreference compound
CAS number835-31-4
MW210.3
Synonyms
Antan; Rhinazine; Imidin;
Transport conditionsNormal

Naphazoline

Naphazoline is sympathomimetic adrenergic alpha-agonist. It is used to induce systemic vasoconstriction, thereby decreasing nasal congestion and inducing constriction around the conjunctiva.

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BRC1008
Product IDBRC1008
Product classBioreference compound
CAS number55206-24-1
MW214.7
Synonyms
Transport conditionsNormal

6-fluorotryptamine hydrochloride

6-fluorotryptamine hydrochloride is a tryptamine derivative that potentially agonizes 5-HT serotonin receptors (EC50 = 4.56 nM).

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BRC0032
Product IDBRC0032
Product classBioreference compound
CAS number41100-52-1
MW215.8
Synonyms
Abixa, Akatinol, Axura, Memox
Transport conditionsNormal

Memantine hydrochloride

Memantine exerts its action through uncompetitive NMDA receptor antagonism, binding preferentially to the NMDA receptor-operated cation channels. Memantine also has antagonistic activity at the type 3 serotonergic (5-HT3) receptor with a potency that is similar to that at the NMDA receptor, and lower antagonistic activity at the nicotinic acetylcholine receptor. This drug has no affinity for γ-aminobutyric acid (GABA), benzodiazepine, dopamine, adrenergic, histamine, or glycine receptors or for voltage-dependent calcium, sodium, or potassium channels.

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BRC0226
Product IDBRC0226
Product classBioreference compound
CAS number125-33-7
MW218.3
Synonyms
Desoxyphenobarbital, Mysoline, Liskantin, Mizodin, Mylepsinum, Pridona, Primid, Prysoline, Sertan
Transport conditionsNormal
Restrictions Included in DEA controlled list

Primidone

An antiepileptic agent related to the barbiturates; it is partly metabolized to phenobarbital in the body and owes some of its actions to this metabolite. Primidone is a GABA receptor agonist.

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BRC0181
Product IDBRC0181
Product classBioreference compound
CAS number50-12-4
MW218.3
Synonyms
Mesantoin
Transport conditionsNormal

Mephenytoin

Mephenytoin is an antiepileptic drug which can be useful in the treatment of epilepsy.

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