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Antifungals

StructureProduct infoAvailabilityQuantity / Price
BRC0594
Product IDBRC0594
Product classBioreference compound
CAS number2022-85-7
MW129.1
Synonyms
5-Fluorocytosine; 5-FC; NSC-103805; RO 2-9915; RO-2-9915;
Transport conditionsNormal

Flucytosine

Flucytosine, a fluorinated pyrimidine analog, is a synthetic antimycotic prodrug that is converted by cytosine deaminase to 5-fluorouracil. It is an antimetabolite that acts as an antifungal agent with in vitro and in vivo activity against Candida and Cryptococcus.

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BRC0859
Product IDBRC0859
Product classBioreference compound
CAS number69-72-7
MW138.1
Synonyms
FEMA NO. 3985; K-557; NSC-180;
Transport conditionsNormal

Salicylic acid

Salicylic acid is bacteriostatic, fungicide and keratolytic agent. It is directly and irreversibly inhibits the activity of COX-1 and COX-2 to decrease the formation of precursors of prostaglandins and thromboxanes from arachidonic acid.

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BRC1029
Product IDBRC1029
Product classBioreference compound
CAS number59-50-7
MW142.6
Synonyms
NSC 4166; Neopredisan; Parol; Raschit; PCMC;
Transport conditionsNormal

Chlorocresol

Chlorocresol is a chlorinated phenol which is used as an antiseptic and preservative.

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BRC1067
Product IDBRC1067
Product classBioreference compound
CAS number652-67-5
MW146.1
Synonyms
NSC 40725; Polysorb; AT 101; Dianhydro-D-glucitol;
Transport conditionsNormal

Isosorbide

Isosorbide is a heterocyclic compound that is derived from glucose, used as osmotic diuretic to treat hydrocephalus.

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BRC0985
Product IDBRC0985
Product classBioreference compound
CAS number89-83-8
MW150.2
Synonyms
NSC-11215; NSC-47821; NSC-49142; IPMP;
Transport conditionsNormal

Thymol

Thymol is an antiseptic, antibacterial, and antifungal agent. It is used as a stabilizer in pharmaceutic preparations.

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BRC0789
Product IDBRC0789
Product classBioreference compound
CAS number174671-46-6
MW151.9
Synonyms
AN 2690, AN 2729, Kerydin
Transport conditionsNormal

Tavaborole

Tavaborole its antifungal medication for the treatment of onychomycosis, blocking cellular protein synthesis through the formation of an adduct with cytoplasmic leucyl-aminoacyl transfer RNA (tRNA) synthetase.

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BRC1071
Product IDBRC1071
Product classBioreference compound
CAS number120-47-8
MW166.2
Synonyms
Mycocten; NSC 23514; NSC 8510; E 214; Easeptol;
Transport conditionsNormal

Ethylparaben

Ethylparaben is the ethyl ester of p-hydroxybenzoic acid, used as an anti-microbial agent and food additive. It is a standardized chemical allergen. The physiologic effect of ethylparaben is by means of increased histamine release, and cell-mediated immunity.

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BRC1081
Product IDBRC1081
Product classBioreference compound
CAS number130-16-5
MW179.6
Synonyms
Dermofungin; NSC 35083; NSC 53182; NSC 74943;
Transport conditionsNormal

Cloxiquine

Cloxiquine is an antibacterial, antifungal, antiaging and antituberculosis agent.

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BRC1118
Product IDBRC1118
Product classBioreference compound
CAS number112-38-9
MW184.3
Synonyms
NSC 2013; Renselin; Sevinon;
Transport conditionsNormal

Undecenoic Acid

Undecenoic acid is a antifungal agent that treats skin infections such as athlete’s foot and relieves itching, burning, and irritation associated with the skin condition. It is also used as a linking molecule to conjugate other biomolecules such as proteins.

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BRC0912
Product IDBRC0912
Product classBioreference compound
CAS number41814-78-2
MW189.2
Synonyms
EL-291, Dhanteam, Gain, MTB, Sivic
Transport conditionsNormal

Tricyclazole

Tricyclazole is a common active ingredient in fungicide products.

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BRC0427
Product IDBRC0427
Product classBioreference compound
CAS number4008-48-4
MW190.2
Synonyms
5-NOK, 8-Hydroxy-5-nitroquinoline
Transport conditionsNormal

Nitroxoline

Nitroxoline is a urinary antibacterial agent active against susceptible gram-positive and gram-negative organisms commonly found in urinary tract infections. It is a fluorquinolone that is active against bacterial gyrases. This drug may also have antitumor activity by inhibition of type 2 methionine aminopeptidase (MetAP2) protein which is involved in angiogenesis.

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BRC1288
Product IDBRC1288
Product classBioreference compound
CAS number111-20-6
MW202.2
Synonyms
NSC 19492; NSC 97405;
Transport conditionsNormal

Sebacic acid

Sebacic Acid is a urinary metabolite, identified as an anti-fatigue biomarker.

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BRC0183
Product IDBRC0183
Product classBioreference compound
CAS number104-29-0
MW202.6
Synonyms
Kolpicortin, Maolate, Rinlaxer
Transport conditionsNormal

Chlorphenesin

Chlorphenesin is a muscle relaxant. It blocks nerve impulses (or pain sensations) that are sent to the brain. The mechanism of action of chlorphenesin is not well defined, and its effects are measured mainly by subjective responses. It is known that chlorphenesin acts in the central nervous system (CNS) rather than directly on skeletal muscle.

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BRC0580
Product IDBRC0580
Product classBioreference compound
CAS number773-76-2
MW214.0
Synonyms
Endiaron; NSC 3904; Quesyl; CHQ;
Transport conditionsNormal

Chloroxine

Chloroxine is a synthetic antibacterial compound. It inhibits the growth of gram-positive as well as some gram-negative organisms.

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BRC1139
Product IDBRC1139
Product classBioreference compound
CAS number496-67-3
MW223.1
Synonyms
Pivadorn; Somnurol; Upiol; Uvaleral;
Transport conditionsNormal

Bromisoval

Bromisoval is a sedative-hypnotic agent that is occasionally combined with non-steroidal anti-inflammatory drugs in over-the-counter products. It suppresses expression of many kinds of pro- and anti-inflammatory mediators in LPS- or interferon-γ activated alveolar and peritoneal macrophages. Bromisoval is used to treat anxiety.

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BRC1052
Product IDBRC1052
Product classBioreference compound
CAS number72-80-0
MW228.1
Synonyms
Acnosan; Afungil; Florabina;
Transport conditionsNormal

Chlorquinaldol

Chlorquinaldol is an antimicrobial agent.

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BRC0876
Product IDBRC0876
Product classBioreference compound
CAS number1707149-00-5
MW279.2
Synonyms
Transport conditionsNormal

N-(3,5-difluorophenyl)-1-methyl-6-oxo-1,6-dihydropyridine-3-carbohydrazide

The compound is novel antifungal oxodihydropyridinecarbohydrazide derivative.

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BRC0419
Product IDBRC0419
Product classBioreference compound
CAS number91161-71-6
MW291.4
Synonyms
SF 86-327, Terbinex
Transport conditionsNormal

Terbinafine

Terbinafine is an allylamine antifungal agent and acts by inhibiting squalene epoxidase, thus blocking the biosynthesis of ergosterol, an essential component of fungal cell membranes.

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BRC1076
Product IDBRC1076
Product classBioreference compound
CAS number130-26-7
MW305.5
Synonyms
Lekosept; NSC 3531; NSC 74938; Nioform;
Transport conditionsNormal

Clioquinol

Clioquinol is a broad-spectrum antibacterial with antifungal properties. It inhibits certain enzymes related to DNA replication.

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BRC0420
Product IDBRC0420
Product classBioreference compound
CAS number86386-73-4
MW306.3
Synonyms
UK 49858, Diflucan, Elazor, Flucazol, Flucostat, Flunizol, Monicure, Pritenzol, Trican, Triflucan
Transport conditionsNormal

Fluconazole

Fluconazole, a synthetic antifungal agent of the imidazole class, is used to treat vaginal candidiasis. It inhibits the fungal lanosterol 14 alpha-demethylase which thereby prevents the formation of ergosterol which is an essential component in the fungal cell membrane.

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BRC0894
Product IDBRC0894
Product classBioreference compound
CAS number60628-96-8
MW310.4
Synonyms
Bay h 4502;
Transport conditionsNormal

Bifonazole

Bifonazole is antifungal, inhibits the production of ergosterol, which is an essential component of fungal cell membranes.

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BRC0388
Product IDBRC0388
Product classBioreference compound
CAS number137234-62-9
MW349.3
Synonyms
DRG 0301, UK 109496, Vfend®, VRC,
Transport conditionsNormal

Voriconazole

Voriconazole is a triazole antifungal agent indicated for use in the treatment of fungal infections including invasive aspergillosis, esophageal candidiasis, and serious fungal infections caused by Scedosporium apiospermum (asexual form of Pseudallescheria boydii) and Fusarium spp. including Fusarium solani.

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BRC0897
Product IDBRC0897
Product classBioreference compound
CAS number126-07-8
MW352.8
Synonyms
Poncyl; Spirofulvin; Sporostatin;
Transport conditionsNormal
Restrictions Included in California Proposition 65 list  WARNING! This product contains a chemical known to the State of California to cause cancer. For more information go to www.P65Warnings.ca.gov.

Griseofulvin

Griseofulvin is an antifungal antibiotic. It binds to tubulin, interfering with microtubule function, thus inhibiting mitosis. It binds to keratin in keratin precursor cells and makes them resistant to fungal infections.

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BRC0954
Product IDBRC0954
Product classBioreference compound
CAS number548-62-9
MW408.0
Synonyms
Methylrosaniline; Atmonil; Avermin; Axuris; Badil;
Transport conditionsNormal

Gentian Violet

Gentian violet is a mutagen, a mitotic poison, and a clastogen. In aqueous solutions, it dissociates into positive (GV+)and negative ions (Cl-) that penetrate through the wall and membrane of both gram-positive and gram-negative bacterial cells.

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BRC0884
Product IDBRC0884
Product classBioreference compound
CAS number121-54-0
MW448.1
Synonyms
BZT, MED 81, Hyamine 1622
Transport conditionsNormal

Benzethonium chloride

Benzethonium chloride is a cationic quaternary ammonium surfactant and anti-infective agent. It is a potent inhibitor of nAChRs.

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BRC0901
Product IDBRC0901
Product classBioreference compound
CAS number65277-42-1
MW531.4
Synonyms
Phytorol, R 41400, Tocon
Transport conditionsNormal

Ketoconazole

Ketoconazole is anti-fungal agent with potent anti-metastatic, anti-neoplastic, and anti-psoriatic activities. It is an inhibitor of cytochrome P-450 in steroid biosynthesis. Also acts as an inhibitor of 5-lipoxygenase and thromboxane synthase activities.

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BRC0047
Product IDBRC0047
Product classBioreference compound
CAS number140-64-7
MW592.7
Synonyms
Pentacarinat
Transport conditionsNormal

Pentamidine isethionate

Pentamidine is an antiprotozoal agent. It is an aromatic diamidine, and is known to have activity against Pneumocystis carinii. It is thought that the drug interferes with nuclear metabolism producing inhibition of the synthesis of DNA, RNA, phospholipids, and proteins.

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BRC0113
Product IDBRC0113
Product classBioreference compound
CAS number84625-61-6
MW705.6
Synonyms
Sporanox, Oriconazole, Hyphanox, R 51211
Transport conditionsNormal

Itraconazole

Itraconazole is an imidazole/triazole type antifungal agent. Itraconazole is a highly selective inhibitor of fungal cytochrome P-450 sterol C-14 α-demethylation via the inhibition of the enzyme cytochrome P450 14α-demethylase.

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