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Steroids

StructureProduct infoAvailabilityQuantity / Price
BRC0684
Product IDBRC0684
Product classBioreference compound
CAS number56-53-1
MW268.4
Synonyms
NSC 3070, DES
Transport conditionsNormal
Restrictions Included in California Proposition 65 list  WARNING! This product contains a chemical known to the State of California to cause cancer and birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

Diethylstilbestrol

Diethylstilbestrol is a synthetic estrogen with carcinogenic properties (estrogen receptor agonist, EC50 = 0.007 nM). Used in the treatment of prostate cancer to block the production of testosterone.

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BRC0796
Product IDBRC0796
Product classBioreference compound
CAS number53-16-7
MW270.4
Synonyms
NSC 9699, WAY 164397
Transport conditionsNormal

Estrone

Estrone is an estradiol metabolite, estrogen receptor agonist.

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BRC0753
Product IDBRC0753
Product classBioreference compound
CAS number50-28-2
MW272.4
Synonyms
E3A, NSC 17590, NSC-20293, NSC-9895, SQ 16150, WC-3011
Transport conditionsNormal
Restrictions Included in California Proposition 65 list  WARNING! This product contains a chemical known to the State of California to cause cancer. For more information go to www.P65Warnings.ca.gov.

Estradiol

Estradiol is endogenous estrogen receptor (ER) agonist (Ki = 0.12 and 0.13 nM for ERα and ERβ respectively). Also high affinity ligand at membrane estrogen GPR30 receptors.

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BRC0787
Product IDBRC0787
Product classBioreference compound
CAS number112809-51-5
MW285.3
Synonyms
CGS 20267, Femara
Transport conditionsNormal

Letrozole

Letrozole is an aromatase inhibitor used in the treatment of breast cancer.

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BRC0088
Product IDBRC0088
Product classBioreference compound
CAS number57-63-6
MW296.4
Synonyms
Ethinyloestradiol, Ethinoral, Lynoral
Transport conditionsNormal
Restrictions Included in California Proposition 65 list  WARNING! This product contains a chemical known to the State of California to cause cancer and birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

Ethinyl Estradiol

Ethinyl estradiol is a synthetic derivative of the natural estrogen estradiol. It is one of two estrogens currently used in oral contraceptive pills. The other, mestranol, is converted to ethinyl estradiol before it is biologically active. Ethinyl estradiol and norethindrone are used together as an oral contraceptive agent.

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BRC0820
Product IDBRC0820
Product classBioreference compound
CAS number72-33-3
MW310.4
Synonyms
NSC 84032, Norquen, Ovastol, SC 4725
Transport conditionsNormal
Restrictions Included in California Proposition 65 list  WARNING! This product contains a chemical known to the State of California to cause health damage. For more information go to www.P65Warnings.ca.gov.

Mestranol

Mestranol is the 3-methyl ether of ethinylestradiol. It is a biologically inactive prodrug of ethinylestradiol to which it is demethylated in the liver with a conversion efficiency of 70%.

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BRC0866
Product IDBRC0866
Product classBioreference compound
CAS number57-83-0
MW314.5
Synonyms
BP 14, NSC-64377, NSC-9704, U 3672
Transport conditionsNormal
Restrictions Included in California Proposition 65 list  WARNING! This product contains a chemical known to the State of California to cause health damage. For more information go to www.P65Warnings.ca.gov.

Progesterone

Progesterone is steroid hormone produced by the corpus luteum. It is endogenous progesterone receptor (PR) agonist (EC50 = 0.5 nM).

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BRC0195
Product IDBRC0195
Product classBioreference compound
CAS number13647-35-3
MW329.4
Synonyms
WIN 24540, Desopan, Modrefen, Vetoryl
Transport conditionsNormal
Restrictions Included in California Proposition 65 list  WARNING! This product contains a chemical known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

Trilostane

Trilostane blocks an enzyme involved in the production of several steroids including cortisol. Inhibiting this enzyme inhibits the production of cortisol.

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BRC0836
Product IDBRC0836
Product classBioreference compound
CAS number50-23-7
MW362.5
Synonyms
NSC-10483
Transport conditionsNormal

Hydrocortisone

Hydrocortisone is steroid hormone of the adrenal cortex with anti-inflammatory properties.

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BRC0786
Product IDBRC0786
Product classBioreference compound
CAS number98319-26-7
MW372.6
Synonyms
MK 906,
Transport conditionsNormal

Finasteride

Finasteride is a competitive and specific inhibitor of Type II 5a-reductase, an intracellular enzyme that converts the androgen testosterone into 5α-dihydrotestosterone (DHT).

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BRC0352
Product IDBRC0352
Product classBioreference compound
CAS number50-02-2
MW392.5
Synonyms
MK 125, NSC 34521
Transport conditionsNormal

Dexamethasone

Dexamethasone is an antiinflammatory glucocorticoid that induces the production of phospholipase A2 inhibitory protein (lipocortin). It also inhibits induction of nitric oxide synthase (IC50=5 nM). Dexamethasone has been shown to cause reduction in cyclin A and Cdk2 activity, inhibition of G1/S transition in osteoblasts and inhibition of phosphorylation of Rb protein in vitro.

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BRC0844
Product IDBRC0844
Product classBioreference compound
CAS number378-44-9
MW392.5
Synonyms
NSC-39470, SCH 4831
Transport conditionsNormal

Betamethasone

Betamethasone is a glucocorticoid receptor agonist.

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BRC0305
Product IDBRC0305
Product classBioreference compound
CAS number83-44-3
MW392.6
Synonyms
NSC-8797, Deoxycholate, Desoxycholic acid, Cholerebic, Cholorebic, ATX-101
Transport conditionsNormal

Deoxycholic acid

Deoxycholic acid is a a bile acid which emulsifies and solubilizes dietary fats in the intestine, and when injected subcutaneously, it disrupts cell membranes in adipocytes and destroys fat cells in that tissue.

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BRC0887
Product IDBRC0887
Product classBioreference compound
CAS number474-25-9
MW392.6
Synonyms
Transport conditionsNormal
Restrictions Included in California Proposition 65 list  WARNING! This product contains a chemical known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

Chenodeoxycholic acid

Chenodeoxycholic acid is an epimer of ursodeoxycholic acid. Chenodeoxycholic acid is a bile acid naturally found in the body. It is potent selective inhibitors of DD2 (AKR1C2).

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BRC0389
Product IDBRC0389
Product classBioreference compound
CAS number128-13-2
MW392.6
Synonyms
Cholit-ursan, Delursan, Destolit, Deursil, Litursol, Solutrat, Ursacol, Ursochol, Ursolvan
Transport conditionsNormal
Restrictions Included in California Proposition 65 list  WARNING! This product contains a chemical known to the State of California to cause health damage. For more information go to www.P65Warnings.ca.gov.

Ursodeoxycholic acid

Ursodiol (also known as ursodeoxycholic acid) is one of the secondary bile acids, which are metabolic byproducts of intestinal bacteria. Ursodeoxycholic acid helps regulate cholesterol by reducing the rate at which the intestine absorbs cholesterol molecules while breaking up micelles containing cholesterol. Because of this property, ursodeoxycholic acid is used to treat gall stones non-surgically.

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BRC0296
Product IDBRC0296
Product classBioreference compound
CAS number84371-65-3
MW429.6
Synonyms
RU 486, RU 38486, C-1073
Transport conditionsNormal

Mifepristone

A progestational and glucocorticoid hormone antagonist.

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BRC0540
Product IDBRC0540
Product classBioreference compound
CAS number261766-32-9
MW461.0
Synonyms
Transport conditionsNormal

LM 4108

LM 4108 is amide derivative of the nonsteroidal anti-inflammatory drug, indomethacin. It selective cyclooxygenase-2 inhibitor (IC50 = 0.04 µM).

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BRC0070
Product IDBRC0070
Product classBioreference compound
CAS number164656-23-9
MW528.5
Synonyms
Avodart, Avolve, GG-745, GI198745
Transport conditionsNormal

Dutasteride

Dutasteride belongs to a class of drugs called 5-alpha-reductase inhibitors, which block the action of the 5-alpha-reductase enzymes that convert testosterone into dihydrotestosterone (DHT).

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BRC0901
Product IDBRC0901
Product classBioreference compound
CAS number65277-42-1
MW531.4
Synonyms
Phytorol, R 41400, Tocon
Transport conditionsNormal

Ketoconazole

Ketoconazole is anti-fungal agent with potent anti-metastatic, anti-neoplastic, and anti-psoriatic activities. It is an inhibitor of cytochrome P-450 in steroid biosynthesis. Also acts as an inhibitor of 5-lipoxygenase and thromboxane synthase activities.

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