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Dipeptidase inhibitor

StructureProduct infoAvailabilityQuantity / Price
BRC0208
Product IDBRC0208
Product classBioreference compound
CAS number82009-34-5
MW358.4
Synonyms
Cilastatin-Natrium
Transport conditionsNormal

Cilastatin

Cilastatin is a renal dehydropeptidase-I and leukotriene D4 dipeptidase inhibitor. Since the antibiotic, imipenem, is hydrolyzed by dehydropeptidase-I, which resides in the brush border of the renal tubule, cilastatin is administered with imipenem to increase its effectiveness. The drug also inhibits the metabolism of leukotriene D4 to leukotriene E4.

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