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Angiotensin-converting enzyme (ACE)

StructureProduct infoAvailabilityQuantity / Price
BRC0890
Product IDBRC0890
Product classBioreference compound
CAS number62571-86-2
MW217.3
Synonyms
C09AA01, SA-333, SQ-14225
Transport conditionsNormal
Restrictions Included in California Proposition 65 list Restriction  WARNING! This product contains a chemical known to the State of California to cause health damage. For more information go to www.P65Warnings.ca.gov.

Captopril

Captopril is a potent, competitive inhibitor of angiotensin-converting enzyme (ACE), the enzyme responsible for the conversion of angiotensin I (ATI) to angiotensin II (ATII). ATII regulates blood pressure and is a key component of the renin-angiotensin-aldosterone system (RAAS).

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BRC0632
Product IDBRC0632
Product classBioreference compound
CAS number23113-43-1
MW267.5
Synonyms
NSC 68982, Wy 8678
Transport conditionsNormal

Guanabenz hydrochloride

Guanabenz is a centrally acting α-2 adrenergic agonist and IGRS (imidazoline I2 binding site) selective ligand, indicated for treatment of hypertension.

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BRC1295
Product IDBRC1295
Product classBioreference compound
CAS number51298-62-5
MW269.7
Synonyms
Transport conditionsNormal

L-NAME hydrochloride

L-NAME hydrochloride is a nonselective inhibitor of nitric oxide synthetases.

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BRC0509
Product IDBRC0509
Product classBioreference compound
CAS number82158-86-9
MW319.4
Synonyms
Kinedak; ONO 2235; Sorbista;
Transport conditionsNormal

Epalrestat

Epalrestat is a carboxylic acid-based inhibitor of aldose reductase (IC50 = 0.01-15 μM). Epalrestat has been shown to reduce oxidative stress in type 2 diabetic patients, significantly decreasing lipid hydroperoxide levels in erythrocytes when administered at 150 mg/day.

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BRC0095
Product IDBRC0095
Product classBioreference compound
CAS number84680-54-6
MW384.4
Synonyms
Enalapril acid, MK-422 Dihydrate
Transport conditionsNormal

Enalaprilat dihydrate

Enalaprilat is the active metabolite of the orally available pro-drug, enalapril. Used in the treatment of hypertension, enalapril is an ACE inhibitor that prevents Angiotensin Converting Enzyme (ACE) from transforming angiotensin I into angiotensin II.

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BRC0855
Product IDBRC0855
Product classBioreference compound
CAS number76547-98-3
MW405.5
Synonyms
MK 521, MK 522
Transport conditionsNormal
Restrictions Included in California Proposition 65 list Restriction  WARNING! This product contains a chemical known to the State of California to cause health damage. For more information go to www.P65Warnings.ca.gov.

Lisinopril

Lisinopril is a potent, competitive inhibitor of angiotensin-converting enzyme, the enzyme responsible for the conversion of angiotensin I (ATI) to angiotensin II (ATII). ATII is a key component of the renin-angiotensin-aldosterone system (RAAS).

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BRC0716
Product IDBRC0716
Product classBioreference compound
CAS number87333-19-5
MW416.5
Synonyms
Corpril, Delix, Ecator, HOE 498
Transport conditionsNormal
Restrictions Included in California Proposition 65 list Restriction  WARNING! This product contains a chemical known to the State of California to cause health damage. For more information go to www.P65Warnings.ca.gov.

Ramipril

Ramipril is non-peptide, competitive angiotensin converting enzyme (ACE) inhibitor (IC50 = 5 nM). It is prodrug which is hydrolyzed in vivo to the active metabolite ramiprilat. Displays protective effects on endothelium against high-glucose induced dysfunction.

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BRC0850
Product IDBRC0850
Product classBioreference compound
CAS number82586-55-8
MW475.0
Synonyms
C09AA06
Transport conditionsNormal

Quinapril hydrochloride

Quinapril hydrochloride is a prodrug, angiotensin-converting enzyme (ACE) inhibitor. It is metabolized to quinaprilat (quinapril diacid) following oral administration. Quinaprilat is a competitive inhibitor of ACE, the enzyme responsible for the conversion of angiotensin I (ATI) to angiotensin II (ATII).

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BRC0681
Product IDBRC0681
Product classBioreference compound
CAS number98048-97-6
MW563.7
Synonyms
Fozitec
Transport conditionsNormal

Fosinopril

Fosinopril is an inhibitor of Angiotensin-converting enzyme (ACE). In nature, ACE converts angiotensin I to angiotensin II, which causes blood vessels to constrict, and thereby increasing blood pressure.

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