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BRC1070
Product IDBRC1070
Product classBioreference compound
CAS number66-22-8
MW112.1
Synonyms
4-Hydroxyuracil; Hybar X; NSC 3970; Pirod;
Transport conditionsNormal

Uracil

Uracil is a pyrimidine derivative, one of the four nucleobases in the nucleic acid of RNA can be used for drug delivery and as a pharmaceutical. Uracil serves as allosteric regulator and coenzyme for reactions in the human body and in plants.

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BRC0594
Product IDBRC0594
Product classBioreference compound
CAS number2022-85-7
MW129.1
Synonyms
5-Fluorocytosine; 5-FC; NSC-103805; RO 2-9915; RO-2-9915;
Transport conditionsNormal

Flucytosine

Flucytosine, a fluorinated pyrimidine analog, is a synthetic antimycotic prodrug that is converted by cytosine deaminase to 5-fluorouracil. It is an antimetabolite that acts as an antifungal agent with in vitro and in vivo activity against Candida and Cryptococcus.

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BRC0031
Product IDBRC0031
Product classBioreference compound
CAS number51-21-8
MW130.1
Synonyms
5-FU, Carzonal, Efudix, Efurix, Ftoruracil, NSC 19893
Transport conditionsNormal
Restrictions Included in California Proposition 65 list  WARNING! This product contains a chemical known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

5-Fluorouracil

Fluorouracil is an antineoplastic anti-metabolite. Anti-metabolites masquerade as purine or pyrimidine - which become the building blocks of DNA. They prevent these substances from becoming incorporated into DNA during the "S" phase (of the cell cycle), stopping normal development and division.

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BRC0622
Product IDBRC0622
Product classBioreference compound
CAS number73-24-5
MW135.1
Synonyms
Vitamin B4;
Transport conditionsNormal

Adenine

Adenine is a purine base that acts as a precursor, substrate, or cofactor in diverse biochemical pathways. It is a fundamental component of DNA, RNA, and ATP, as well as numerous other natural biochemicals.

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BRC1290
Product IDBRC1290
Product classBioreference compound
CAS number97-59-6
MW158.1
Synonyms
NSC 7606; Psoralon; SD 101; Sebical;
Transport conditionsNormal

Allantoin

Allantoin is a purine metabolite via the uric acid pathway. It may be a useful biomarker for oxidative stress.

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BRC0952
Product IDBRC0952
Product classBioreference compound
CAS number154-42-7
MW167.2
Synonyms
6-TG; NSC-752; NSC-76504; Wellcome U 3 B;
Transport conditionsNormal
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Tioguanine

Thioguanine is an antineoplastic compound which also has antimetabolite action, used in the treatment of several forms of leukemia including acute nonlymphocytic leukemia.

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BRC1078
Product IDBRC1078
Product classBioreference compound
CAS number149-91-7
MW170.1
Synonyms
NSC 20103; NSC 674319;
Transport conditionsNormal

Gallic acid

Gallic acid is an anti-inflammatory agent and cyclooxygenase inhibitor found in plants and has been shown to Induce apoptosis in human lung cancer cells. It is often used as a standard for determining the phenol content of various analytes by the Folin-Ciocalteau assay where results are reported in gallic acid equivalents.

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BRC0102
Product IDBRC0102
Product classBioreference compound
CAS number6112-76-1
MW170.2
Synonyms
Purinethol, 6-Thiopurine,
Transport conditionsNormal

6-Mercaptopurine monohydrate

Mercaptopurine is one of a large series of purine analogues which interfere with nucleic acid biosynthesis and has been found active against human leukemias. It is an analogue of the purine bases adenine and hypoxanthine. It is not known exactly which of any one or more of the biochemical effects of mercaptopurine and its metabolites are directly or predominantly responsible for cell death.

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BRC0170
Product IDBRC0170
Product classBioreference compound
CAS number443-48-1
MW171.2
Synonyms
Flagyl, Trichopol, Vagilen
Transport conditionsNormal
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Metronidazole

Metronidazole, a synthetic antibacterial and antiprotozoal agent of the nitroimidazole class, is used against protozoa. Metronidazole is a prodrug. Unionized metronidazole is selective for anaerobic bacteria due to their ability to intracellularly reduce metronidazole to its active form.

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BRC0467
Product IDBRC0467
Product classBioreference compound
CAS number64984-31-2
MW181.2
Synonyms
NSC 30358
Transport conditionsNormal

Pifithrin-μ

Pifithrin-μ (PFT-μ) is an inhibitor of p53-mediated apoptosis, preventing p53 binding to Bcl-xL and Bcl-2 at the mitochondria without affecting p53 transactivational activities.

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BRC1104
Product IDBRC1104
Product classBioreference compound
CAS number459-86-9
MW184.2
Synonyms
NSC 32946; MGBG;
Transport conditionsNormal

Mitoguazone

Mitoguazone is a drug used in chemotherapy, in trials studying the treatment of Lymphoma, HIV Infections, and Non-Hodgkin Lymphoma.

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BRC0210
Product IDBRC0210
Product classBioreference compound
CAS number4812-40-2
MW187.2
Synonyms
Metronidazole-OH;
Transport conditionsNormal

Hydroxymetronidazole

Hydroxymetronidazole is a metabolite of metronidazole.

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BRC1121
Product IDBRC1121
Product classBioreference compound
CAS number123-99-9
MW188.2
Synonyms
Finacea; Lepargylic acid; NSC 19493; Skinoren; ZK 62498;
Transport conditionsNormal

Azelaic Acid

Azelaic acid is an anti-inflammatory agent. It directly inhibits kallikrein 5 (KLK5), downregulating expression of KLK5, toll-like receptor 2 (TLR 2), and cathelicidin, and suppresses activity of serine proteases in vitro, in vivo, and in clinical settings.

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BRC0277
Product IDBRC0277
Product classBioreference compound
CAS number52-24-4
MW189.2
Synonyms
Thioplex;
Transport conditionsNormal
Restrictions Included in California Proposition 65 list  WARNING! This product contains a chemical known to the State of California to cause cancer. For more information go to www.P65Warnings.ca.gov.

Thiotepa

Thiotepa is a cancer chemotherapeutic member of the alkylating agent group.

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BRC0164
Product IDBRC0164
Product classBioreference compound
CAS number85622-93-1
MW194.2
Synonyms
BRN 5547136, CCRG 81045, CCRIS 8996, MB 39831, Methazolastone, NSC 362856, Sch 52365, Temodal, Temodar, TMZ
Transport conditionsNormal

Temozolomide

Temozolomide is an imidazotetrazine deritave and an antineoplastic agent. It is a prodrug that has little to no pharmacological activity until it is hydrolyzed in vivo to 5-(3-methyltriazen-1-yl)imidazole-4-carboxamide (MTIC).

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BRC0295
Product IDBRC0295
Product classBioreference compound
CAS number58-08-2
MW194.2
Synonyms
Methyltheobromine, NSC 5036
Transport conditionsNormal

Caffeine

Central nervous system stimulant. Antagonist at A1 and A2A adenosine receptors and inhibitor of cyclic nucleotide phosphodiesterases. Mobilizes calcium from intracellular stores and inhibits benzodiazepine binding to GABA receptors.

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BRC0322
Product IDBRC0322
Product classBioreference compound
CAS number6960-45-8
MW206.2
Synonyms
NSC 69877, 7-NO2-ICA, 7-Nitroindole-2-Carboxylic Acid
Transport conditionsNormal

CRT0044876

DNA Base Excision Repair Pathway Inhibitor is a potent, nontoxic, specific, and cell-permeable DNA repair enzyme inhibitor.

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BRC0304
Product IDBRC0304
Product classBioreference compound
CAS number3160-91-6
MW207.7
Synonyms
Influcol, Spenitol, ABOB, SKF 8898-A
Transport conditionsNormal

Moroxydine hydrochloride

Moroxydine hydrochloride is a synthetic antiviral drug chemically belonging to the series of the heterocyclic biguanidines.

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BRC0182
Product IDBRC0182
Product classBioreference compound
CAS number645-05-6
MW210.3
Synonyms
Hexalen, Hexamethylmelamine, HMM, NSC13875, ENT50852
Transport conditionsNormal
Restrictions Included in California Proposition 65 list  WARNING! This product contains a chemical known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

Altretamine

Altretamine is a novel antineoplastic agent. 

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BRC0225
Product IDBRC0225
Product classBioreference compound
CAS number154-93-8
MW214.0
Synonyms
BCNU; Bicnu; Gliadel; Becenun; Nitrumon; NSC 409962;
Transport conditionsNormal
Restrictions Included in California Proposition 65 list  WARNING! This product contains a chemical known to the State of California to cause cancer and birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

Carmustine

Carmustine is a nitrogen mustard ?-chloro-nitrosourea compound that is used as an alkylating agent.

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BRC0431
Product IDBRC0431
Product classBioreference compound
CAS number1501-84-4
MW215.8
Synonyms
Flumadine
Transport conditionsNormal

Rimantadine hydrochloride

Rimantadine, a cyclic amine, is a synthetic antiviral drug and a derivate of adamantane, like a similar drug amantadine.

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BRC0896
Product IDBRC0896
Product classBioreference compound
CAS number298-81-7
MW216.2
Synonyms
8-MOP, 9-Methoxypsoralen, NSC-45923
Transport conditionsNormal
Restrictions Included in California Proposition 65 list  WARNING! This product contains a chemical known to the State of California to cause cancer. For more information go to www.P65Warnings.ca.gov.

Methoxsalen

Methoxsalen is a naturally occurring furocoumarin compound, that selectively inhibits the synthesis of deoxyribonucleic acid (DNA) in the presence of ultraviolet A irradiation.

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BRC0135
Product IDBRC0135
Product classBioreference compound
CAS number67-45-8
MW225.2
Synonyms
Furoxone, Nitrofurazolidone, Nitrofuroxon, USAF EA-1
Transport conditionsNormal
Restrictions Included in California Proposition 65 list  WARNING! This product contains a chemical known to the State of California to cause cancer. For more information go to www.P65Warnings.ca.gov.

Furazolidone

Furazolidone and its related free radical products are believed to bind DNA and induce cross-links. Its bactericidal activity is based upon its interference with DNA replication and protein production; this antimicrobial action minimizes the development of resistant organisms.

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BRC0831
Product IDBRC0831
Product classBioreference compound
CAS number59277-89-3
MW225.2
Synonyms
NSC-645011, BW 248U
Transport conditionsNormal

Aciclovir

Aciclovir is a synthetic deoxyguanosine analog and it is the prototype antiviral agent that is activated by viral thymidine kinase.

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BRC0412
Product IDBRC0412
Product classBioreference compound
CAS number2353-33-5
MW228.2
Synonyms
Deoxycytidine, 5-aza-2’-Deoxycytidine, DAC, Dacogen, NSC 127716,
Transport conditionsNormal

Decitabine

Decitabine is an analogue of the natural nucleoside 2’-deoxycytidine. It functions in the same way as 5-Azacytidine. The antineoplastic activity of this drug is dependent on its intracellular conversion to its 5'-triphosphate metabolite.

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BRC0074
Product IDBRC0074
Product classBioreference compound
CAS number3902-71-4
MW228.2
Synonyms
Trimethylpsoralen,
Transport conditionsNormal

Trioxsalen

Trioxsalen is a pigmenting photosensitizing agent used in conjunction with ultraviolet light in the treatment of vitiligo. Trioxsalen is pharmacologically inactive but when exposed to ultraviolet radiation or sunlight it is converted to its active metabolite to produce a beneficial reaction affecting the diseased tissue. After photoactivation it creates interstrand cross-links in DNA, which can cause programmed cell death.

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BRC0773
Product IDBRC0773
Product classBioreference compound
CAS number134678-17-4
MW229.2
Synonyms
GR 109714X, Hepitec, Zefix, BCH 189, (-)-, GR 109714X,
Transport conditionsNormal

Lamivudine

Lamivudine is a nucleoside reverse transcriptase inhibitor with activity against Human Immunodeficiency Virus Type 1 (HIV-1) and hepatitis B (HBV).

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BRC0408
Product IDBRC0408
Product classBioreference compound
CAS number389-08-2
MW232.2
Synonyms
NSC-82174
Transport conditionsNormal
Restrictions Included in California Proposition 65 list  WARNING! This product contains a chemical known to the State of California to cause cancer. For more information go to www.P65Warnings.ca.gov.

Nalidixic Acid

Nalidixic acid is a quinolone antibacterial agent for oral administration. Nalidixic acid has marked antibacterial activity against gram-negative bacteria including Enterobacter species, Escherichia coli, Morganella Morganii; Proteus Mirabilis, Proteus vulgaris, and Providencia rettgeri. Pseudomonas species are generally resistant to the drug.

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BRC1393
Product IDBRC1393
Product classBioreference compound
CAS number88343-72-0
MW236.7
Synonyms
Chlorethyl SOSO; NSC 338947;
Transport conditionsNormal

Clomesone

Clomesone is an antineoplastic agent, DNA inhibitor.

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BRC0407
Product IDBRC0407
Product classBioreference compound
CAS number3424-98-4
MW242.2
Synonyms
LDT, 2'-Deoxy-L-thymidine, Epavudine
Transport conditionsNormal

Telbivudine

Telbivudine is a synthetic thymidine nucleoside analogue with activity against hepatitis B virus (HBV). Telbivudine is the unmodified β–L enantiomer of the naturally occurring nucleoside, thymidine. It undergoes phosphorylation via interaction with cellular kinases to form the active metabolite, telbivudine 5'-triphosphate.

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BRC0057
Product IDBRC0057
Product classBioreference compound
CAS number147-94-4
MW243.2
Synonyms
Ara-C, Cytosine arabinoside, Cytosar, Arabinosylcytosine,
Transport conditionsNormal
Restrictions Included in California Proposition 65 list  WARNING! This product contains a chemical known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

Cytarabine

Cytarabine is an antineoplastic anti-metabolite used in the treatment of several forms of leukemia including acute myelogenous leukemia and meningeal leukemia.

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BRC0115
Product IDBRC0115
Product classBioreference compound
CAS number320-67-2
MW244.2
Synonyms
Ladakamycin, Vidaza, NSC 102816
Transport conditionsNormal
Restrictions Included in California Proposition 65 list  WARNING! This product contains a chemical known to the State of California to cause cancer. For more information go to www.P65Warnings.ca.gov.

Azacitidine

Azacitidine (5-azacytidine) is a chemical analogue of the cytosine nucleoside used in DNA and RNA. Azacitidine is believed to exert its antineoplastic effects by causing hypomethylation of DNA and direct cytotoxicity on abnormal hematopoietic cells in the bone marrow. The concentration of azacitidine required for maximum inhibition of DNA methylation in vitro does not cause major suppression of DNA synthesis.

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BRC0178
Product IDBRC0178
Product classBioreference compound
CAS number36791-04-5
MW244.2
Synonyms
RBV; Rebretron; Ribamide; Vilona; Viramid; Virazide; NSC-163039; ICN-1229; RTCA; Tribavirin;
Transport conditionsNormal
Restrictions Included in California Proposition 65 list  WARNING! This product contains a chemical known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

Ribavirin

Ribavirin is a guanosine analog with antiviral properties against DNA and RNA viruses, including respiratory syncytial virus, hepatitis C, and influenza.

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BRC0351
Product IDBRC0351
Product classBioreference compound
CAS number50-91-9
MW246.2
Synonyms
NSC 26740, NSC 27640, 5-FDU, 5-Fluorodeoxyuridine
Transport conditionsNormal

Floxuridine

Antineoplastic antimetabolite. Exhibits antiproliferative activity; inhibits thymidylate synthetase and disrupts DNA replication in human cells. Induces double-strand DNA breaks; activates ATR and ATM signaling pathways. Induces phosphorylation of Chk1 and Chk2 in OVCAR-8 and SKOV3ip ovarian cancer cell lines.

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BRC0041
Product IDBRC0041
Product classBioreference compound
CAS number55-98-1
MW246.3
Synonyms
Busulphan, Mielosan, Milecitan, Myeloleukon, Mylecytan, Myleran, NCI C01592, NSC 750
Transport conditionsNormal
Restrictions Included in California Proposition 65 list  WARNING! This product contains a chemical known to the State of California to cause cancer and birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

Busulfan

Busulfan is an antineoplastic in the class of alkylating agents and is used to treat various forms of cancer.

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BRC0238
Product IDBRC0238
Product classBioreference compound
CAS number19387-91-8
MW247.3
Synonyms
Fasigyn, CP12574
Transport conditionsNormal

Tinidazole

Tinidazole is a prodrug and antiprotozoal agent. The nitro group of tinidazole is reduced in Trichomonas by a ferredoxin-mediated electron transport system. The free nitro radical generated as a result of this reduction is believed to be responsible for the antiprotozoal activity.

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BRC0893
Product IDBRC0893
Product classBioreference compound
CAS number39809-25-1
MW253.3
Synonyms
BRL-39123; PCV; PE2;
Transport conditionsNormal

Penciclovir

Penciclovir is a guanosine analog with antiviral activity, an active metabolite of the oral product famciclovir. It has in vitro activity against herpes simplex virus types 1 and 2.

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BRC0233
Product IDBRC0233
Product classBioreference compound
CAS number82410-32-0
MW255.2
Synonyms
GA2, Cytovene, Vitrasert, RS-21592, BW-759
Transport conditionsNormal
Restrictions Included in California Proposition 65 list  WARNING! This product contains a chemical known to the State of California to cause cancer and birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

Ganciclovir

Ganciclovir is a synthetic nucleoside analogue of 2'-deoxyguanosine that inhibits replication of herpes viruses both in vitro and in vivo. Ganciclovir is a prodrug that is structurally similar to acyclovir.

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BRC0099
Product IDBRC0099
Product classBioreference compound
CAS number366-70-1
MW257.8
Synonyms
Natulan, Ibenzmethyzin, NSC-77213 HCl
Transport conditionsNormal
Restrictions Included in California Proposition 65 list  WARNING! This product contains a chemical known to the State of California to cause cancer and birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

Procarbazine hydrochloride

Procarbazine is an antineoplastic in the class of alkylating agents and is used to treat various forms of cancer.

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BRC0121
Product IDBRC0121
Product classBioreference compound
CAS number50-35-1
MW258.2
Synonyms
Thalomid, Distaval, Softenon, Talimol,
Transport conditionsNormal
Restrictions Included in California Proposition 65 list  WARNING! This product contains a chemical known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

Thalidomide

Thalidomide is an immunomodulatory agent with a spectrum of activity that is not fully characterized. Thalidomide is racemic — it contains both left and right handed isomers in equal amounts: one enantiomer is effective against morning sickness, and the other is teratogenic.

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BRC0698
Product IDBRC0698
Product classBioreference compound
CAS number28657-80-9
MW262.2
Synonyms
Compound 64716, NSC 304467, Noxigram, Uronorm
Transport conditionsNormal

Cinoxacin

Cinoxacin is an antibacterial quinolone analog of oxolinic acid with in vitro activity against many gram-negative aerobic bacteria. It blocks DNA synthesis through inhibition of Topo II (DNA gyrase) as well as topoisomerase IV.

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BRC0771
Product IDBRC0771
Product classBioreference compound
CAS number95058-81-4
MW263.2
Synonyms
LY188011, NSC 613327, Zefei, DDFC
Transport conditionsNormal

Gemcitabine

Gemcitabine is an antineoplastic anti-metabolite that inhibits DNA synthesis.

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BRC0942
Product IDBRC0942
Product classBioreference compound
CAS number614-39-1
MW271.8
Synonyms
NSC-27461; Biocoryl;
Transport conditionsNormal

Procainamide hydrochloride

Procainamide hydrochloride is a potent blocker of sodium channels. It demonstrates antiarrhythmic effects correlated with blockade of the Na+ channels. Procainamide hydrochloride is DNA methyltransferase inhibitor.

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BRC0941
Product IDBRC0941
Product classBioreference compound
CAS number51-05-8
MW272.8
Synonyms
Novocaine; Vitamin H3; Duracaine; NSC 169497; Nissocaine;
Transport conditionsNormal

Procaine Hydrochloride

Procaine hydrochloride is a local anesthetic. It is mainly used for infiltration anesthesia, peripheral nerve block, and spinal block. It is a sodium channel blocker with a variety of inhibitory effects. Procaine is also noted to act as a DNA methylation inhibitor and to cause demethylation and reactivation of methylation-silenced genes such as RARβ and GSTP1.

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BRC0380
Product IDBRC0380
Product classBioreference compound
CAS number6055-19-2
MW279.1
Synonyms
B 518, NSC 26271, Endoxan
Transport conditionsNormal
Restrictions Included in California Proposition 65 list  WARNING! This product contains a chemical known to the State of California to cause cancer and birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

Cyclophosphamide monohydrate

Cyclophosphamide is a nitrogen mustard alkylating agent used in the treatment of cancers and autoimmune disorders. In cells with low levels of aldehyde dehydrogenase, cyclophosphamide acts as a prodrug since it is metabolized to the active compound phosphoramide mustard, which crosslinks with DNA and causes cell death.

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BRC0995
Product IDBRC0995
Product classBioreference compound
CAS number21679-14-1
MW285.2
Synonyms
NSC-118218; 2-F-ARAA;
Transport conditionsNormal

Fludarabine

Fludarabine is purine analog that inhibits DNA synthesis. It exhibits antiproliferative activity (IC50 = 1.54 μM in RPMI cells). Inhibits cytokine-induced activation of STAT1 and STAT1-dependent gene transcription in lymphocytes. Also displays anticancer activity against hematological malignancies in vivo.

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BRC0265
Product IDBRC0265
Product classBioreference compound
CAS number34156-56-4
MW300.0
Synonyms
Carboxyphosphonic acid, Phosphonoformate, Phosphonoformic acid, Triapten,
Transport conditionsNormal

Foscarnet Sodium Hexahydrate

Foscarnet is an organic analogue of inorganic pyrophosphate that inhibits replication of herpes viruses in vitro including cytomegalovirus (CMV) and herpes simplex virus types 1 and 2 (HSV-1 and HSV-2).

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BRC0775
Product IDBRC0775
Product classBioreference compound
CAS number1143525-19-2
MW301.3
Synonyms
NSC 19994, Vernine
Transport conditionsNormal

Guanosine hydrate

Guanosine is a nucleoside comprising guanine attached to a ribose (ribofuranose) ring via a β-N9-glycosidic bond. It is required as a coenzyme for protein biosynthesis in a cell-free system.

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BRC0545
Product IDBRC0545
Product classBioreference compound
CAS number330786-24-8
MW303.3
Synonyms
Transport conditionsNormal

3-(4-Phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine

The compound is a highly selective Bruton’s tyrosine kinase (BTK) irreversible inhibitor (IC50 < 10 µM) and useful synthetic intermediate in the synthesis of Ibrutinib.

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BRC0209
Product IDBRC0209
Product classBioreference compound
CAS number123318-82-1
MW303.7
Synonyms
CAFdA, CL-F-Ara-a, Clofarex, Clolar, Evoltra, Clofarex,
Transport conditionsNormal

Clofarabine

Clofarabine is a purine nucleoside antimetabolite that is being studied in the treatment of cancer.

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