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MYC (c-Myc, proto-oncogene proteins)

StructureProduct infoAvailabilityQuantity / Price
BRC0452
Product IDBRC0452
Product classBioreference compound
CAS number1485-00-3
MW193.2
Synonyms
NSC 10120, NSC 105303, NSC 170724, Syk Inhibitor III
Transport conditionsNormal

MNS

MNS is selective inhibitor of Src and Syk tyrosine kinases. Displays antiaggregative activity via inhibition of GPIIb/IIIa activation (IC50 = 12.7 μM for thrombin-induced platelet aggregation). Exhibits no effects on Ca2+-dependent enzymes, PKC or arachidonic acid metabolism.

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BRC0324
Product IDBRC0324
Product classBioreference compound
CAS number403811-55-2
MW249.4
Synonyms
Transport conditionsNormal

10058-F4

10058-F4 is a c-Myc inhibitor that prevents c-Myc/Max dimerization. c-Myc is a proto-oncogene that plays an important role in cell proliferation, differentiation, and apoptosis.

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BRC0503
Product IDBRC0503
Product classBioreference compound
CAS number22816-60-0
MW271.6
Synonyms
Transport conditionsNormal

A 22 hydrochloride

A22 s a cell-permeable isothiourea compound that inhibits MreB, an actin-like bacterial protein, and has been shown to act as an antiobiotic adjuvant.

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BRC0545
Product IDBRC0545
Product classBioreference compound
CAS number330786-24-8
MW303.3
Synonyms
Transport conditionsNormal

3-(4-Phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine

The compound is a highly selective Bruton’s tyrosine kinase (BTK) irreversible inhibitor (IC50 < 10 µM) and useful synthetic intermediate in the synthesis of Ibrutinib.

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BRC0793
Product IDBRC0793
Product classBioreference compound
CAS number710323-58-3
MW356.2
Synonyms
GSK 3 Inhibitor IX; MLS 2052; 6-Bromoindirubin-3-oxime;
Transport conditionsNormal

BIO

BIO is a cell-permeable, highly potent, selective, reversible and ATP-competitive glycogen synthase kinase-3 inhibitor. Maintains self-renewal and pluripotency in embryonic stem cells via activation of the Wnt signaling pathway in vitro. Also, promotes proliferation and dedifferentiation in cardiomyocytes.

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BRC0766
Product IDBRC0766
Product classBioreference compound
CAS number863405-60-1
MW456.5
Synonyms
Transport conditionsNormal

JW74

JW 74 is an inhibitor of canonical Wnt signaling (IC50 = 790 nM). Targets the β-catenin destruction complex (GSK-3 beta /AXIN/APC). Decreases active β-catenin levels in colorectal cancer (CRC) cells. Also, arrests cell cycle in G1 and inhibits proliferation of CRC cells in vitro.

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