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Poly (ADP-ribose) polymerase (PARP)

StructureProduct infoAvailabilityQuantity / Price
BRC0961
Product IDBRC0961
Product classBioreference compound
CAS number98-92-0
MW122.1
Synonyms
Niacinamide; Nicotinic Acid Amide; NSC 13128; NSC 27452;
Transport conditionsNormal

Nicotinamide

Nicotinamide is an amide form of vitamin B3 (niacin), anti-inflammatory agent. It is poly(ADP-ribose) polymerase (PARP-1) enzymes inhibitor. NAD+ precursor. Promotes differentiation of mesenchymal stem cells to insulin-producing cells when used in combination with growth factors and high glucose concentration.

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BRC1068
Product IDBRC1068
Product classBioreference compound
CAS number3544-24-9
MW136.2
Synonyms
NSC 36962; SR 4294; WD 97-000835;
Transport conditionsNormal

INO-1001

INO-1001 is PARP (poly(ADP-ribose) polymerase) inhibitor (Ki = 1.8 μM), which protects cells from UV-B-induced apoptosis via influence on the cytoskeleton. Through its effects on PARPs, 3-amino benzamide causes telomere shortening and stimulates angiogenesis. It has PARP-mediated actions in such diverse diseases as atherosclerosis, neurogenesis, and cancer.

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BRC1290
Product IDBRC1290
Product classBioreference compound
CAS number97-59-6
MW158.1
Synonyms
NSC 7606; Psoralon; SD 101; Sebical;
Transport conditionsNormal

Allantoin

Allantoin is a purine metabolite via the uric acid pathway. It may be a useful biomarker for oxidative stress.

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BRC0724
Product IDBRC0724
Product classBioreference compound
CAS number420849-22-5
MW201.2
Synonyms
Transport conditionsNormal

TIQ-A

TIQ-A is a cell permeable, potent PARP-1 inhibitor (IC50 = 495 nM). Neuroprotective against oxygen-glucose deprivation injury in vitro in cultured murine cortical cells.

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