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Fluorinated amines


The fluorine atom is electronegative and reduces the basicity of adjacent amines, however, it is relatively small: only about 20% larger than hydrogen and significantly smaller that chlorine resulting in unique and useful properties. In many cases incorporation of fluorine results in improved DMPK properties. Below you will find examples of mono-fluoro, di-fluoro and trifluoromethyl substituted amines, many with a hydroxyl substituent or an ether linkage.

Search returned 606 hits.

StructureProduct infoAvailabilityQuantity / Price
Catalog IDEN300-115962
Product class Building Block
Name2,2-difluoroethan-1-amine
ACD numberMFCD00798137
CAS number430-67-1
Formula
MW81.1
CLogP-0.089
Storage conditionsRT
Transport conditionsNormal
See details
Purity: 95%Global stock:> 10 g(5 business days)   USA Rush delivery(2 business days)
available in New Jersey stock : 1x0.25 g, 1x0.5 g, 1x1 g
Catalog IDEN300-149340
Product class Building Block
Name2-amino-3-fluoropropan-1-ol
ACD numberMFCD19215451
CAS number166665-93-6
Formula
MW93.1
CLogP-1.113
Storage conditions+4
Transport conditionsNormal
See details
Purity: 95%Global stock:0.4 g(5 business days)  
Catalog IDEN300-194473
Product class Building Block
Name2-fluoroethan-1-amine hydrochloride
ACD numberMFCD00008161
CAS number460-08-2
Formula
MW99.5
CLogP-0.412
Storage conditionsRT
Transport conditionsNormal
See details
Purity: 95%Global stock:> 10 g(5 business days)   EU Rush delivery : (2 business days)
1x0.25 g, 1x0.5 g, 1x1 g
Catalog IDEN300-6970573
Product class Building Block
Name3-(fluoromethyl)oxetan-3-amine
ACD numberMFCD31727894
CAS number1782527-32-5
Formula
MW105.1
CLogP-0.095
Storage conditions-10
Transport conditionsIce pack
See details
Purity: 95%Global stock:> 10 g(5 business days)   USA Rush delivery(2 business days)
available in New Jersey stock : 1x1 g
Catalog IDEN300-204507
Product class Building Block
Name(3-fluoroazetidin-3-yl)methanol
ACD numberMFCD18633069
CAS number1268520-93-9
Formula
MW105.1
CLogP-0.908
Storage conditions+4
Transport conditionsNormal
See details
Now available as 91% pureGlobal stock:0.8 g(5 business days)  
Catalog IDEN300-175608
Product class Building Block
Name2-amino-4-fluorobutan-1-ol
ACD numberMFCD19216262
CAS number1314976-96-9
Formula
MW107.1
CLogP-1.034
Storage conditions+4
Transport conditionsNormal
See details
Purity: 95%Global stock:4.5 g(5 business days)  
Catalog IDEN300-100454
Product class Building Block
Name3-amino-1,1-difluoropropan-2-ol
ACD numberMFCD16805790
CAS number433-46-5
Formula
MW111.1
CLogP-0.94
Storage conditions-10
Transport conditionsIce pack
See details
Purity: 95%Global stock:> 10 g(5 business days)   USA Rush delivery(2 business days)
available in New Jersey stock : 1x1 g
Catalog IDEN300-190781
Product class Building Block
Name2-(difluoromethoxy)ethan-1-amine
ACD numberMFCD28397342
CAS number1599344-15-6
Formula
MW111.1
CLogP-0.226
Storage conditions-10
Transport conditionsIce pack
See details
Purity: 95%Global stock:> 10 g(5 business days)  
Catalog IDEN300-139846
Product class Building Block
Name3-amino-2,2-difluoropropan-1-ol
ACD numberMFCD19207959
CAS number155310-11-5
Formula
MW111.1
CLogP-0.011
Storage conditions+4
Transport conditionsNormal
See details
Purity: 95%Global stock:> 10 g(5 business days)   USA Rush delivery(2 business days)
available in New Jersey stock : 1x0.25 g, 1x0.5 g, 1x1 g, 1x2.5 g, 1x5 g
Catalog IDEN300-7461074
Product class Building Block
Name2-fluoroprop-2-en-1-amine hydrochloride
ACD numberMFCD17014871
CAS number322637-47-8
Formula
MW111.5
CLogP0.213
Storage conditionsRT
Transport conditionsNormal
See details
Purity: 95%Global stock:> 10 g(5 business days)   USA Rush delivery(2 business days)
available in New Jersey stock : 1x0.001 g, 1x0.002 g, 1x0.005 g, 1x0.01 g, 1x0.02 g, 1x0.025 g, 1x0.05 g, 1x0.1 g, 1x0.25 g, 1x0.5 g, 1x1 g
Catalog IDEN300-89604
Product class Building Block
Name1,1,1-trifluoropropan-2-amine
ACD numberMFCD04973020
CAS number421-49-8
Formula
MW113.1
CLogP0.438
Storage conditions+4
Transport conditionsIce pack
See details
Purity: 95%Global stock:> 10 g(5 business days)  
Catalog IDEN300-344955
Product class Building Block
Name5-fluoropyrimidin-2-amine
ACD numberMFCD11846500
CAS number1683-85-8
Formula
MW113.1
CLogP-0.135
Storage conditionsRT
Transport conditionsNormal
See details
Purity: 95%Global stock:9.4 g(5 business days)  
Catalog IDEN300-7461639
Product class Building Block
Name3-fluoropropan-1-amine hydrochloride
ACD numberMFCD07369956
CAS number64068-31-1
Formula
MW113.6
CLogP-0.183
Storage conditions+4
Transport conditionsIce pack
See details
Purity: 95%Global stock:> 10 g(5 business days)   USA Rush delivery(2 business days)
available in New Jersey stock : 2x0.25 g, 2x0.5 g, 2x1 g
Catalog IDEN300-214040
Product class Building Block
Name1-fluoropropan-2-amine hydrochloride
ACD numberMFCD20489620
CAS number921602-78-0
Formula
MW113.6
CLogP-0.103
Storage conditionsRT
Transport conditionsNormal
See details
Purity: 95%Global stock:> 10 g(5 business days)   EU Rush delivery : (2 business days)
1x0.001 g, 1x0.002 g, 1x0.005 g, 1x0.01 g, 1x0.02 g, 1x0.025 g, 1x0.05 g, 1x0.1 g, 1x0.25 g, 1x0.5 g, 1x1 g
Catalog IDEN300-1081128
Product class Building Block
NameO-(2-fluoroethyl)hydroxylamine hydrochloride
ACD numberMFCD13196691
CAS number95068-26-1
Formula
MW115.5
CLogP-0.801
Storage conditions+4
Transport conditionsNormal
See details
Purity: 95%Global stock:> 10 g(5 business days)   USA Rush delivery(2 business days)
available in New Jersey stock : 1x0.001 g, 1x0.002 g, 1x0.005 g, 1x0.01 g, 1x0.02 g, 1x0.025 g, 1x0.05 g, 1x0.1 g, 1x0.25 g, 1x0.5 g, 1x1 g
Catalog IDEN300-200827
Product class Building Block
Name2-(1-fluorocyclobutyl)ethan-1-amine
ACD numberMFCD28246495
CAS number1803593-31-8
Formula
MW117.2
CLogP0.94
Storage conditions-10
Transport conditionsIce pack
See details
Purity: 95%Global stock:7.6 g(5 business days)   USA Rush delivery(2 business days)
available in New Jersey stock : 1x1 g
Catalog IDEN300-96615
Product class Building Block
Name2,2-difluoroethan-1-amine hydrochloride
ACD numberMFCD04038283
CAS number79667-91-7
Formula
MW117.5
CLogP-0.089
Storage conditionsRT
Transport conditionsNormal
See details
Purity: 95%Global stock:> 10 g(5 business days)   EU Rush delivery : (2 business days)
1x0.25 g, 1x0.5 g, 1x1 g
Catalog IDEN300-6430616
Product class Building Block
Name3-(difluoromethyl)oxetan-3-amine
ACD numberMFCD32663199
CAS number1779926-68-9
Formula
MW123.1
CLogP-0.072
Storage conditions-10
Transport conditionsIce pack
See details
Purity: 95%Global stock:> 10 g(5 business days)   USA Rush delivery(2 business days)
available in New Jersey stock : 1x1 g
Catalog IDEN300-156762
Product class Building Block
Name3-(difluoromethoxy)azetidine
ACD numberMFCD28132440
CAS number1403993-56-5
Formula
MW123.1
CLogP0.403
Storage conditions-10
Transport conditionsIce pack
See details
Now available as 85% pureGlobal stock:5.2 g(5 business days)  
Catalog IDEN300-90869
Product class Building Block
Name2-(trifluoromethyl)azetidine
ACD numberMFCD11042768
CAS number1040331-55-2
Formula
MW125.1
CLogP0.51
Storage conditions-10
Transport conditionsIce pack
See details
Purity: 95%Global stock:> 10 g(5 business days)   USA Rush delivery(2 business days)
available in New Jersey stock : 4x1 g
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