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Morpholine mimetics


Morpholine, a six-member-ring system containing both oxygen and nitrogen, is considerable less basic than its parent piperidine (pkas of 8.4 and 11.2 respectively). Ring systems incorporating morpholine are found in many natural products and drug molecules and are useful in exploring structure activity relationships. The EnamineStore has over 1000 such analogues containing spiro, bridged and fused examples. See selected examples below:
StructureProduct infoAvailabilityQuantity / Price
Catalog IDEN300-1091632
Product class Building Block
Name4-methyl-1,3-oxazinane
ACD numberMFCD31559826
CAS number267419-10-3
Formula
MW101.1
CLogP0.181
Storage conditions+4
Transport conditionsNormal
Purity: 95%Global stock:7.2 g(5 business days)   USA Rush delivery(2 business days)
available in New Jersey stock: 1 g 1x0.25, 1x0.5, 1x1
Catalog IDEN300-708637
Product class Building Block
Namerac-(3aR,6aR)-hexahydrofuro[3,4-d][1,2]oxazole, cis
ACD numberMFCD31665904
CAS number2227843-18-5
Formula
MW115.1
CLogP-0.45
Storage conditions+4
Transport conditionsNormal
Purity: 95%Global stock:> 10 g(5 business days)   USA Rush delivery(2 business days)
available in New Jersey stock: 1 g 1x0.25, 1x0.5, 1x1
Catalog IDEN300-2007913
Product class Building Block
Name(S)-1,4-oxazepan-6-ol
ACD numberMFCD22201127
CAS number1373232-31-5
Formula
MW117.1
CLogP-0.9
Storage conditions+4
Transport conditionsNormal
Purity: 95%Global stock:1.9 g(5 business days)  
Catalog IDEN300-75420
Product class Building Block
Name3-methoxyazetidine hydrochloride
ACD numberMFCD06804514
CAS number148644-09-1
Formula
MW123.6
CLogP0.097
Storage conditionsRT
Transport conditionsNormal
Purity: 95%Global stock:> 10 g(5 business days)  
Catalog IDEN300-208936
Product class Building Block
Name6-oxa-2-azaspiro[3.5]nonane
ACD numberMFCD14581252
CAS number1214875-08-7
Formula
MW127.2
CLogP0.113
Storage conditions-10
Transport conditionsIce pack
Purity: 95%Global stock:> 10 g(5 business days)   USA Rush delivery(2 business days)
available in Ohio stock: 1 g 1x0.25, 1x0.5, 1x1
Catalog IDEN300-105822
Product class Building Block
Name2-oxa-7-azaspiro[4.4]nonane
ACD numberMFCD14581261
CAS number175-97-3
Formula
MW127.2
CLogP-0.109
Storage conditionsRT
Transport conditionsNormal
Purity: 95%Global stock:> 10 g(5 business days)   USA Rush delivery(2 business days)
available in New Jersey stock: 1 g 1x0.25, 1x0.5, 1x1EU Rush delivery(5 g)(2 business days)
1x0.25, 1x0.5, 1x1, 1x2.5, 1x5
Catalog IDEN300-252467
Product class Building Block
Namerac-(4aR,7aS)-octahydrofuro[3,4-b]pyridine, cis
ACD numberMFCD29055426
CAS number1807939-96-3
Formula
MW127.2
CLogP0.419
Storage conditions+4
Transport conditionsNormal
Purity: 95%Global stock:> 10 g(5 business days)  
Catalog IDEN300-804985
Product class Building Block
Nameoctahydropyrano[4,3-b]pyrrole
ACD numberMFCD24447823
CAS number1517624-23-5
Formula
MW127.2
CLogP-0.239
Storage conditions+4
Transport conditionsNormal
Purity: 95%Global stock:> 10 g(5 business days)   USA Rush delivery(2 business days)
available in New Jersey stock: 1 g 1x0.25, 1x0.5, 1x1
Catalog IDEN300-2963532
Product class Building Block
NameN-cyclobutyloxetan-3-amine
ACD numberMFCD18849537
CAS number1341378-53-7
Formula
MW127.2
CLogP0.703
Storage conditions+4
Transport conditionsNormal
Purity: 95%Global stock:> 10 g(5 business days)   USA Rush delivery(2 business days)
available in New Jersey stock: 1 g 1x0.25, 1x0.5, 1x1
Catalog IDEN300-200454
Product class Building Block
Name7-oxa-1-azaspiro[4.4]nonane
ACD numberMFCD14581262
CAS number128389-81-1
Formula
MW127.2
CLogP0.067
Storage conditions+4
Transport conditionsNormal
Purity: 95%Global stock:3.8 g(5 business days)  
Catalog IDEN300-303385
Product class Building Block
Namerac-(2R,7S)-2,7-dimethyl-1,4-oxazepane, cis
ACD numberMFCD30181810
CAS number1955515-06-6
Formula
MW129.2
CLogP0.661
Storage conditionsRT
Transport conditionsNormal
Purity: 95%Global stock:> 10 g(5 business days)   USA Rush delivery(2 business days)
available in Ohio stock: 5 g 1x0.25, 1x0.5, 1x1, 1x2.5, 1x5
Catalog IDEN300-321528
Product class Building Block
Name1-ethoxypiperazine
ACD numberMFCD19221321
CAS number1314933-43-1
Formula
MW130.2
CLogP0.676
Storage conditions+4
Transport conditionsIce pack
Purity: 95%Global stock:8.9 g(5 business days)   USA Rush delivery(2 business days)
available in New Jersey stock: 1 g 1x0.25, 1x0.5, 1x1
Catalog IDEN300-367266
Product class Building Block
Name4-methyl-1,4lambda5-azaphosphinan-4-one
ACD numberMFCD19227137
CAS number945460-43-5
Formula
MW133.1
CLogP-0.736
Storage conditions+4
Transport conditionsIce pack
Purity: 95%Global stock:> 10 g(5 business days)   USA Rush delivery(2 business days)
available in New Jersey stock: 1 g 1x0.002, 1x0.005, 1x0.01, 1x0.02, 1x0.025, 1x0.05, 1x0.1, 1x0.25, 1x0.5, 1x1
Catalog IDEN300-7493296
Product class Building Block
Namerac-(1R,5S)-3-oxa-6-azabicyclo[3.2.0]heptane hydrochloride, cis
ACD numberMFCD28892299
CAS number2408936-87-6
Formula
MW135.6
CLogP-0.347
Storage conditions+4
Transport conditionsNormal
Purity: 95%Global stock:> 10 g(5 business days)  
Catalog IDEN300-651665
Product class Building Block
Namerac-(1R,5R)-2-oxa-6-azabicyclo[3.2.0]heptane hydrochloride, cis
ACD numberMFCD31542434
CAS number2137895-62-4
Formula
MW135.6
CLogP-0.653
Storage conditions+4
Transport conditionsNormal
Purity: 95%Global stock:> 10 g(5 business days)  
Catalog IDEN300-99596
Product class Building Block
Name(S)-3-methoxypyrrolidine hydrochloride
ACD numberMFCD11849817
CAS number685828-16-4
Formula
MW137.6
CLogP-0.169
Storage conditions+4
Transport conditionsNormal
Purity: 95%Global stock:> 10 g(5 business days)  
Catalog IDEN300-178618
Product class Building Block
Nameoxan-3-amine hydrochloride
ACD numberMFCD08059238
CAS number675112-58-0
Formula
MW137.6
CLogP-0.275
Storage conditionsRT
Transport conditionsNormal
Purity: 95%Global stock:> 10 g(5 business days)   USA Rush delivery(2 business days)
available in Ohio stock: 1 g 1x0.25, 1x0.5, 1x1EU Rush delivery(1 g)(2 business days)
1x0.25, 1x0.5, 1x1
Catalog IDEN300-312488
Product class Building Block
Name4-oxa-9-azatricyclo[5.3.0.0,2,6]decane
ACD numberMFCD30476184
CAS number2059937-00-5
Formula
MW139.2
CLogP-0.706
Storage conditions+4
Transport conditionsNormal
Purity: 95%Global stock:7.5 g(5 business days)   USA Rush delivery(2 business days)
available in New Jersey stock: 1 g 1x0.25, 1x0.5, 1x1
Catalog IDEN300-1722997
Product class Building Block
Name8-oxa-5-azaspiro[3.6]decane
ACD numberMFCD31689929
CAS number1251713-04-8
Formula
MW141.2
CLogP0.496
Storage conditions+4
Transport conditionsNormal
Purity: 95%Global stock:> 10 g(5 business days)   USA Rush delivery(2 business days)
available in New Jersey stock: 1 g 1x0.25, 1x0.5, 1x1
Catalog IDEN300-115251
Product class Building Block
Name3-(oxolan-3-yl)pyrrolidine
ACD numberMFCD16707136
CAS number1121057-47-3
Formula
MW141.2
CLogP0.098
Storage conditions+4
Transport conditionsNormal
Purity: 95%Global stock:4.7 g(5 business days)  
Catalog IDEN300-205914
Product class Building Block
Name7-oxa-2-azaspiro[4.5]decane
ACD numberMFCD14581264
CAS number72088-42-7
Formula
MW141.2
CLogP0.32
Storage conditionsRT
Transport conditionsNormal
Purity: 95%Global stock:> 10 g(5 business days)  
Catalog IDEN300-98629
Product class Building Block
Name8-oxa-1-azaspiro[4.5]decane
ACD numberMFCD14581266
CAS number51130-63-3
Formula
MW141.2
CLogP-0.032
Storage conditionsRT
Transport conditionsNormal
Purity: 95%Global stock:> 10 g(5 business days)   USA Rush delivery(2 business days)
available in Ohio stock: 5 g 1x0.25, 1x0.5, 1x1, 1x2.5, 1x5
Catalog IDEN300-697622
Product class Building Block
Name7-oxa-1-azaspiro[4.5]decane
ACD numberMFCD14581265
CAS number82742-26-5
Formula
MW141.2
CLogP0.496
Storage conditionsRT
Transport conditionsNormal
Purity: 95%Global stock:> 10 g(5 business days)   USA Rush delivery(2 business days)
available in Ohio stock: 5 g 1x0.25, 1x0.5, 1x1, 1x2.5, 1x5
Catalog IDEN300-110343
Product class Building Block
Nameoctahydro-2H-pyrano[3,2-c]pyridine, Mixture of diastereomers
ACD numberMFCD18073359
CAS number71671-81-3
Formula
MW141.2
CLogP0.32
Storage conditionsRT
Transport conditionsNormal
Purity: 95%Global stock:> 10 g(5 business days)   USA Rush delivery(2 business days)
available in Ohio stock: 0.25 g 1x0.25EU Rush delivery(1 g)(2 business days)
1x0.25, 1x0.5, 1x1
Catalog IDEN300-96084
Product class Building Block
Name8-oxa-2-azaspiro[4.5]decane
ACD numberMFCD12028170
CAS number310-93-0
Formula
MW141.2
CLogP-0.032
Storage conditionsRT
Transport conditionsNormal
Purity: 95%Global stock:> 10 g(5 business days)  
Catalog IDEN300-204317
Product class Building Block
Name2-(oxolan-2-yl)pyrrolidine
ACD numberMFCD02663538
CAS number383127-91-1
Formula
MW141.2
CLogP0.626
Storage conditionsRT
Transport conditionsNormal
Purity: 95%Global stock:> 10 g(5 business days)   USA Rush delivery(2 business days)
available in Ohio stock: 1 g 1x0.25, 1x0.5, 1x1EU Rush delivery(1 g)(2 business days)
1x0.25, 1x0.5, 1x1
Catalog IDEN300-1672563
Product class Building Block
Name9-oxa-5-azaspiro[3.6]decane
ACD numberMFCD29042951
CAS number1251713-00-4
Formula
MW141.2
CLogP0.496
Storage conditions+4
Transport conditionsNormal
Purity: 95%Global stock:> 10 g(5 business days)   USA Rush delivery(2 business days)
available in New Jersey stock: 1 g 1x0.002, 1x0.005, 1x0.01, 1x0.02, 1x0.025, 1x0.05, 1x0.1, 1x0.25, 1x0.5, 1x1
Catalog IDEN300-746138
Product class Building Block
Namerac-(3aR,4R,6aS)-4-methoxy-octahydrocyclopenta[c]pyrrole
ACD number
CAS number2174000-23-6
Formula
MW141.2
CLogP0.416
Storage conditions+4
Transport conditionsNormal
Purity: 95%Global stock:> 10 g(5 business days)   USA Rush delivery(2 business days)
available in New Jersey stock: 1 g 1x0.25, 1x0.5, 1x1
Catalog IDEN300-132111
Product class Building Block
Namerac-(3aR,6aS)-hexahydro-1H-furo[3,4-c]pyrrole hydrochloride, cis
ACD numberMFCD20527059
CAS number2351095-72-0
Formula
MW149.6
CLogP-0.316
Storage conditions+4
Transport conditionsNormal
Purity: 95%Global stock:> 10 g(5 business days)   EU Rush delivery(1 g)(2 business days)
1x0.25, 1x0.5, 1x1
Catalog IDEN300-312471
Product class Building Block
Name5-oxa-2-azaspiro[3.4]octane hydrochloride
ACD numberMFCD21364490
CAS number1359656-11-3
Formula
MW149.6
CLogP-0.094
Storage conditions+4
Transport conditionsNormal
Purity: 95%Global stock:> 10 g(5 business days)  
Catalog IDEN300-26977606
Product class Building Block
Namerac-(1R,6R)-3-oxa-7-azabicyclo[4.2.0]octane hydrochloride, cis
ACD number
CAS number
Formula
MW149.6
CLogP
Storage conditions+4
Transport conditionsNormal
Purity: 95%Global stock:> 10 g(5 business days)  
Catalog IDEN300-133936
Product class Building Block
Name6-oxa-3-azabicyclo[3.2.1]octane hydrochloride
ACD numberMFCD25970397
CAS number1461708-41-7
Formula
MW149.6
CLogP-0.14
Storage conditionsRT
Transport conditionsNormal
Purity: 95%Global stock:> 10 g(5 business days)   EU Rush delivery(1 g)(2 business days)
1x0.25, 1x0.5, 1x1
Catalog IDEN300-256027
Product class Building Block
Name6-oxa-1-azaspiro[3.4]octane hydrochloride
ACD numberMFCD27920764
CAS number1909319-43-2
Formula
MW149.6
CLogP-0.492
Storage conditionsRT
Transport conditionsNormal
Purity: 95%Global stock:5.5 g(5 business days)  
Catalog IDEN300-341973
Product class Building Block
Name2-oxa-3-azabicyclo[2.2.2]octane hydrochloride
ACD numberMFCD30502176
CAS number110590-22-2
Formula
MW149.6
CLogP0.531
Storage conditionsRT
Transport conditionsNormal
Purity: 95%Global stock:> 10 g(5 business days)   USA Rush delivery(2 business days)
available in Ohio stock: 5 g 1x0.25, 1x0.5, 1x1, 1x2.5, 1x5
Catalog IDEN300-1704474
Product class Building Block
Name6-oxa-2-azabicyclo[3.2.1]octane hydrochloride
ACD numberMFCD31666238
CAS number2219379-77-6
Formula
MW149.6
CLogP-0.14
Storage conditionsRT
Transport conditionsNormal
Purity: 95%Global stock:> 10 g(5 business days)  
Catalog IDEN300-364997
Product class Building Block
Name2H,3H,4H,5H-pyrido[2,3-f][1,4]oxazepine
ACD numberMFCD26710348
CAS number1526186-14-0
Formula
MW150.2
CLogP0.299
Storage conditions+4
Transport conditionsNormal
Purity: 95%Global stock:> 10 g(5 business days)  
Catalog IDEN300-123494
Product class Building Block
Name3-methoxypiperidine hydrochloride
ACD numberMFCD07781094
CAS number688809-94-1
Formula
MW151.6
CLogP0.39
Storage conditions+4
Transport conditionsNormal
Purity: 95%Global stock:> 10 g(5 business days)   EU Rush delivery(1 g)(2 business days)
1x0.25, 1x0.5, 1x1
Catalog IDEN300-30331
Product class Building Block
Name4-methoxypiperidine hydrochloride
ACD numberMFCD06800959
CAS number4045-25-4
Formula
MW151.6
CLogP-0.436
Storage conditionsRT
Transport conditionsNormal
Purity: 95%Global stock:> 10 g(5 business days)  
Catalog IDEN300-251623
Product class Building Block
Name(1S,4S)-2-thia-5-azabicyclo[2.2.1]heptane hydrochloride
ACD numberMFCD20487628
CAS number125136-43-8
Formula
MW151.7
CLogP0.388
Storage conditions+4
Transport conditionsNormal
Purity: 95%Global stock:> 10 g(5 business days)   USA Rush delivery(2 business days)
available in New Jersey stock: 1 g 1x0.002, 1x0.005, 1x0.01, 1x0.02, 1x0.025, 1x0.05, 1x0.1, 1x0.25, 1x0.5, 1x1
Catalog IDEN300-118087
Product class Building Block
Name3-(oxan-4-yl)pyrrolidine
ACD numberMFCD16746204
CAS number1247566-45-5
Formula
MW155.2
CLogP0.527
Storage conditionsRT
Transport conditionsNormal
Purity: 95%Global stock:9.3 g(5 business days)   EU Rush delivery(1 g)(2 business days)
1x0.25, 1x0.5, 1x1
Catalog IDEN300-1461636
Product class Building Block
Name8-OXA-1-AZASPIRO[5.5]UNDECANE
ACD numberMFCD22069641
CAS number867178-17-4
Formula
MW155.2
CLogP1.055
Storage conditionsRT
Transport conditionsNormal
Purity: 95%Global stock:> 10 g(5 business days)   USA Rush delivery(2 business days)
available in New Jersey stock: 1 g 1x0.002, 1x0.005, 1x0.01, 1x0.02, 1x0.025, 1x0.05, 1x0.1, 1x0.25, 1x0.5, 1x1
Catalog IDEN300-97807
Product class Building Block
Name2-oxa-8-azaspiro[5.5]undecane
ACD numberMFCD18073358
CAS number67952-11-8
Formula
MW155.2
CLogP0.879
Storage conditionsRT
Transport conditionsNormal
Purity: 95%Global stock:> 10 g(5 business days)  
Catalog IDEN300-155697
Product class Building Block
Name4-(oxolan-2-yl)piperidine
ACD numberMFCD11040366
CAS number1314966-66-9
Formula
MW155.2
CLogP0.657
Storage conditionsRT
Transport conditionsNormal
Purity: 95%Global stock:1.9 g(5 business days)   EU Rush delivery(1 g)(2 business days)
1x0.25, 1x0.5, 1x1
Catalog IDEN300-183387
Product class Building Block
Name1-oxa-8-azaspiro[5.5]undecane
ACD numberMFCD18073357
CAS number70399-19-8
Formula
MW155.2
CLogP1.055
Storage conditionsRT
Transport conditionsNormal
Purity: 95%Global stock:1.9 g(5 business days)   USA Rush delivery(2 business days)
available in Ohio stock: 1 g 1x0.25, 1x0.5, 1x1
Catalog IDEN300-2988832
Product class Building Block
Name6,6-dimethyl-7-oxa-1-azaspiro[3.5]nonane
ACD numberMFCD21304115
CAS number1478748-54-7
Formula
MW155.2
CLogP0.447
Storage conditions+4
Transport conditionsIce pack
Purity: 95%Global stock:> 10 g(5 business days)   USA Rush delivery(2 business days)
available in New Jersey stock: 1 g 1x0.002, 1x0.005, 1x0.01, 1x0.02, 1x0.025, 1x0.05, 1x0.1, 1x0.25, 1x0.5, 1x1
Catalog IDEN300-1605260
Product class Building Block
Name8-THIA-2-AZASPIRO[4.5]DECANE
ACD numberMFCD16737819
CAS number310-94-1
Formula
MW157.3
CLogP1.018
Storage conditionsRT
Transport conditionsNormal
Purity: 95%Global stock:6.8 g(5 business days)   USA Rush delivery(2 business days)
available in New Jersey stock: 1 g 1x0.25, 1x0.5, 1x1
Catalog IDEN300-1692802
Product class Building Block
Name5-OXA-2-AZASPIRO[3.5]NON-7-ENE HCL
ACD numberMFCD27978669
CAS number1823869-00-6
Formula
MW161.6
CLogP0.181
Storage conditions+4
Transport conditionsNormal
Purity: 95%Global stock:> 10 g(5 business days)   USA Rush delivery(2 business days)
available in New Jersey stock: 1 g 1x0.002, 1x0.005, 1x0.01, 1x0.02, 1x0.025, 1x0.05, 1x0.1, 1x0.25, 1x0.5, 1x1
Catalog IDEN300-133818
Product class Building Block
Name3-methanesulfonylpiperidine
ACD numberMFCD09942240
CAS number290328-56-2
Formula
MW163.2
CLogP-0.759
Storage conditionsRT
Transport conditionsNormal
Purity: 95%Global stock:> 10 g(5 business days)   USA Rush delivery(2 business days)
available in Ohio stock: 1 g 1x0.25, 1x0.5, 1x1
Catalog IDEN300-23566283
Product class Building Block
Name5-oxa-8-azaspiro[2.6]nonane hydrochloride
ACD numberMFCD28894611
CAS number
Formula
MW163.6
CLogP0.289
Storage conditionsRT
Transport conditionsNormal
Purity: 95%Global stock:> 10 g(5 business days)  
Catalog IDEN300-191423
Product class Building Block
Name3-(oxolan-3-yl)azetidine hydrochloride
ACD numberMFCD28125179
CAS number1795438-09-3
Formula
MW163.6
CLogP-0.461
Storage conditionsRT
Transport conditionsNormal
Purity: 95%Global stock:> 10 g(5 business days)   USA Rush delivery(2 business days)
available in Ohio stock: 5 g 1x0.25, 1x0.5, 1x1, 1x2.5, 1x5EU Rush delivery(1 g)(2 business days)
1x0.25, 1x0.5, 1x1
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