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Morpholine mimetics


Morpholine, a six-member-ring system containing both oxygen and nitrogen, is considerable less basic than its parent piperidine (pkas of 8.4 and 11.2 respectively). Ring systems incorporating morpholine are found in many natural products and drug molecules and are useful in exploring structure activity relationships. The EnamineStore has over 1000 such analogues containing spiro, bridged and fused examples. See selected examples below:

Search returned 196 hits.

StructureProduct infoAvailabilityQuantity / Price
Catalog IDEN300-1091632
Product class Building Block
Name4-methyl-1,3-oxazinane
ACD numberMFCD31559826
CAS number267419-10-3
Formula
MW101.1
CLogP0.181
Storage conditions+4
Transport conditionsNormal
See details
Purity: 95%Global stock:6.9 g(5 business days)   USA Rush delivery(2 business days)
available in New Jersey stock : 1x1 g
Catalog IDEN300-708637
Product class Building Block
Namerac-(3aR,6aR)-hexahydrofuro[3,4-d][1,2]oxazole, cis
ACD numberMFCD31665904
CAS number2227843-18-5
Formula
MW115.1
CLogP-0.45
Storage conditions+4
Transport conditionsNormal
See details
Purity: 95%Global stock:> 10 g(5 business days)   USA Rush delivery(2 business days)
available in New Jersey stock : 1x1 g
Catalog IDEN300-75420
Product class Building Block
Name3-methoxyazetidine hydrochloride
ACD numberMFCD06804514
CAS number148644-09-1
Formula
MW123.6
CLogP0.097
Storage conditionsRT
Transport conditionsNormal
See details
Purity: 95%Global stock:> 10 g(5 business days)   EU Rush delivery : (2 business days)
1x5 g
Catalog IDEN300-208936
Product class Building Block
Name6-oxa-2-azaspiro[3.5]nonane
ACD numberMFCD14581252
CAS number1214875-08-7
Formula
MW127.2
CLogP0.113
Storage conditions-10
Transport conditionsIce pack
See details
Purity: 95%Global stock:> 10 g(5 business days)  
Catalog IDEN300-105822
Product class Building Block
Name2-oxa-7-azaspiro[4.4]nonane
ACD numberMFCD14581261
CAS number175-97-3
Formula
MW127.2
CLogP-0.109
Storage conditionsRT
Transport conditionsNormal
See details
Purity: 95%Global stock:> 10 g(5 business days)   EU Rush delivery : (2 business days)
1x5 g
Catalog IDEN300-252467
Product class Building Block
Namerac-(4aR,7aS)-octahydrofuro[3,4-b]pyridine, cis
ACD numberMFCD29055426
CAS number1807939-96-3
Formula
MW127.2
CLogP0.419
Storage conditions+4
Transport conditionsNormal
See details
Purity: 95%Global stock:> 10 g(5 business days)  
Catalog IDEN300-804985
Product class Building Block
Nameoctahydropyrano[4,3-b]pyrrole
ACD numberMFCD24447823
CAS number1517624-23-5
Formula
MW127.2
CLogP-0.239
Storage conditions+4
Transport conditionsNormal
See details
Purity: 95%Global stock:> 10 g(5 business days)  
Catalog IDEN300-2963532
Product class Building Block
NameN-cyclobutyloxetan-3-amine
ACD numberMFCD18849537
CAS number1341378-53-7
Formula
MW127.2
CLogP0.703
Storage conditions+4
Transport conditionsNormal
See details
Purity: 95%Global stock:> 10 g(5 business days)  
Catalog IDEN300-303385
Product class Building Block
Namerac-(2R,7S)-2,7-dimethyl-1,4-oxazepane
ACD numberMFCD30181810
CAS number1955515-06-6
Formula
MW129.2
CLogP0.661
Storage conditionsRT
Transport conditionsNormal
See details
Purity: 95%Global stock:> 10 g(5 business days)   USA Rush delivery(2 business days)
available in New Jersey stock : 1x5 g
Catalog IDEN300-321528
Product class Building Block
Name1-ethoxypiperazine
ACD numberMFCD19221321
CAS number1314933-43-1
Formula
MW130.2
CLogP0.676
Storage conditions+4
Transport conditionsIce pack
See details
Purity: 95%Global stock:8.9 g(5 business days)  
Catalog IDEN300-367266
Product class Building Block
Name4-methyl-1,4lambda5-azaphosphinan-4-one
ACD numberMFCD19227137
CAS number945460-43-5
Formula
MW133.1
CLogP-0.736
Storage conditions+4
Transport conditionsIce pack
See details
Purity: 95%Global stock:> 10 g(5 business days)  
Catalog IDEN300-7493296
Product class Building Block
Namerac-(1R,5S)-3-oxa-6-azabicyclo[3.2.0]heptane hydrochloride, cis
ACD numberMFCD28892299
CAS number2408936-87-6
Formula
MW135.6
CLogP-0.347
Storage conditions+4
Transport conditionsNormal
See details
Purity: 95%Global stock:> 10 g(5 business days)   USA Rush delivery(2 business days)
available in New Jersey stock : 1x1 g
Catalog IDEN300-651665
Product class Building Block
Namerac-(1R,5R)-2-oxa-6-azabicyclo[3.2.0]heptane hydrochloride
ACD numberMFCD31542434
CAS number2137895-62-4
Formula
MW135.6
CLogP-0.653
Storage conditions+4
Transport conditionsNormal
See details
Purity: 95%Global stock:7.7 g(5 business days)   USA Rush delivery(2 business days)
available in New Jersey stock : 1x1 g
Catalog IDEN300-99596
Product class Building Block
Name(S)-3-methoxypyrrolidine hydrochloride
ACD numberMFCD11849817
CAS number685828-16-4
Formula
MW137.6
CLogP-0.169
Storage conditions+4
Transport conditionsNormal
See details
Purity: 95%Global stock:> 10 g(5 business days)  
Catalog IDEN300-178618
Product class Building Block
Nameoxan-3-amine hydrochloride
ACD numberMFCD08059238
CAS number675112-58-0
Formula
MW137.6
CLogP-0.275
Storage conditionsRT
Transport conditionsNormal
See details
Purity: 95%Global stock:> 10 g(5 business days)   EU Rush delivery : (2 business days)
1x1 gUSA Rush delivery(2 business days)
available in New Jersey stock : 2x1 g
Catalog IDEN300-312488
Product class Building Block
Name4-oxa-9-azatricyclo[5.3.0.0,2,6]decane
ACD numberMFCD30476184
CAS number2059937-00-5
Formula
MW139.2
CLogP-0.706
Storage conditions+4
Transport conditionsNormal
See details
Purity: 95%Global stock:7.2 g(5 business days)   USA Rush delivery(2 business days)
available in New Jersey stock : 1x1 g
Catalog IDEN300-1722997
Product class Building Block
Name8-oxa-5-azaspiro[3.6]decane
ACD numberMFCD31689929
CAS number1251713-04-8
Formula
MW141.2
CLogP0.496
Storage conditions+4
Transport conditionsNormal
See details
Purity: 95%Global stock:> 10 g(5 business days)   USA Rush delivery(2 business days)
available in New Jersey stock : 1x1 g
Catalog IDEN300-115251
Product class Building Block
Name3-(oxolan-3-yl)pyrrolidine
ACD numberMFCD16707136
CAS number1121057-47-3
Formula
MW141.2
CLogP0.098
Storage conditions+4
Transport conditionsNormal
See details
Now available as 94% pureGlobal stock:4.8 g(5 business days)  
Catalog IDEN300-98629
Product class Building Block
Name8-oxa-1-azaspiro[4.5]decane
ACD numberMFCD14581266
CAS number51130-63-3
Formula
MW141.2
CLogP-0.032
Storage conditionsRT
Transport conditionsNormal
See details
Purity: 95%Global stock:> 10 g(5 business days)   USA Rush delivery(2 business days)
available in New Jersey stock : 1x5 g
Catalog IDEN300-697622
Product class Building Block
Name7-oxa-1-azaspiro[4.5]decane
ACD numberMFCD14581265
CAS number82742-26-5
Formula
MW141.2
CLogP0.496
Storage conditionsRT
Transport conditionsNormal
See details
Purity: 95%Global stock:> 10 g(5 business days)   USA Rush delivery(2 business days)
available in New Jersey stock : 1x5 g
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