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Sulfonyl chlorides and their utile synthetic equivalents


Sulfonyl or sulphonyl chlorides are reactive derivatives of sulphonic acids and are used to prepare sulphonamides. The sulphonamide group is relatively stable, and found in many marketed drugs, such as antibacterial agents, diuretics, anti-convulsants and PDE-5 inhibitors. The EnamineStore contains a wide range of readily available sulfonyl chlorides: these contain groups like protected amines, nitriles, alicyclic and heterocyclic ring systems. We suggest the following selected compounds for your review:
StructureProduct infoAvailabilityQuantity / Price
Catalog IDEN300-98200
Product classBuilding Block
Nameethenesulfonyl chloride
ACD numberMFCD19200056
CAS number6608-47-5
Formula
MW126.6
CLogP-0.888
Storage conditions+4
Transport conditionsIce pack
Global stock:> 10 g(5 business days)  
Catalog IDEN300-112730
Product classBuilding Block
NameN-methylsulfamoyl chloride
ACD numberMFCD00126938
CAS number10438-96-7
Formula
MW129.6
CLogP-0.869
Storage conditions+4
Transport conditionsNormal
Global stock:> 10 g(5 business days)  
EU rush delivery(2 business days)EU Rush: 1x0.1gEU Rush: 1x0.25gEU Rush: 1x0.5gEU Rush: 1x1g  
Catalog IDEN300-138820
Product classBuilding Block
Namefluoromethanesulfonyl chloride
ACD numberMFCD19200094
CAS number42497-69-8
Formula
MW132.5
CLogP-1.66
Storage conditions-10
Transport conditionsIce pack
Global stock:> 10 g(5 business days)  
USA rush delivery(2 business days)USA Rush: 1x0.1gUSA Rush: 1x0.25gUSA Rush: 1x0.5g  
Catalog IDEN300-1723962
Product classBuilding Block
Name(1Z)-buta-1,3-diene-1-sulfonyl fluoride
ACD numberMFCD31667668
CAS number
Formula
MW136.1
CLogP1.135
Storage conditions-10
Transport conditionsIce pack
Global stock:> 10 g(5 business days)  
USA rush delivery(2 business days)USA Rush: 1x0.1gUSA Rush: 1x0.25gUSA Rush: 1x0.5gUSA Rush: 1x1g  
Catalog IDEN300-151791
Product classBuilding Block
Nameprop-2-yne-1-sulfonyl chloride
ACD numberMFCD19596879
CAS number32623-88-4
Formula
MW138.6
CLogP-1.233
Storage conditions-10
Transport conditionsIce pack
Global stock:3.7 g(5 business days)  
USA rush delivery(2 business days)USA Rush: 1x0.1g  
Catalog IDEN300-50576
Product classBuilding Block
Namecyanomethanesulfonyl chloride
ACD numberMFCD11646184
CAS number27869-04-1
Formula
MW139.6
CLogP-1.837
Storage conditions-10
Transport conditionsIce pack
Global stock:> 10 g(5 business days)  
USA rush delivery(2 business days)USA Rush: 1x0.1g  
Catalog IDEN300-817899
Product classBuilding Block
Name2-oxopropane-1-sulfonyl fluoride
ACD numberMFCD31559714
CAS number1888879-29-5
Formula
MW140.1
CLogP-0.524
Storage conditions+4
Transport conditionsNormal
Global stock:> 10 g(5 business days)  
USA rush delivery(2 business days)USA Rush: 1x0.1gUSA Rush: 1x0.25gUSA Rush: 1x0.5gUSA Rush: 1x1g  
Catalog IDEN300-66998
Product classBuilding Block
Namecyclopropanesulfonyl chloride
ACD numberMFCD01631933
CAS number139631-62-2
Formula
MW140.6
CLogP-0.749
Storage conditions+4
Transport conditionsNormal
Global stock:> 10 g(5 business days)  
EU rush delivery(2 business days)EU Rush: 1x1g  
Catalog IDEN300-103670
Product classBuilding Block
Nameprop-1-ene-2-sulfonyl chloride
ACD numberMFCD19200127
CAS number874009-75-3
Formula
MW140.6
CLogP-0.579
Storage conditions-10
Transport conditionsIce pack
Global stock:6.7 g(5 business days)  
Catalog IDEN300-761367
Product classBuilding Block
Name1-ethynylcyclopropane-1-sulfonyl fluoride
ACD numberMFCD31559372
CAS number2137823-37-9
Formula
MW148.2
CLogP1.0
Storage conditions+4
Transport conditionsNormal
Global stock:> 10 g(5 business days)  
USA rush delivery(2 business days)USA Rush: 1x0.1gUSA Rush: 1x0.25gUSA Rush: 1x0.5gUSA Rush: 1x1g  
Catalog IDEN300-252900
Product classBuilding Block
Name1H-pyrrole-2-sulfonyl fluoride
ACD numberMFCD29762745
CAS number1909325-87-6
Formula
MW149.1
CLogP1.479
Storage conditions-10
Transport conditionsIce pack
Global stock:2.4 g(5 business days)  
USA rush delivery(2 business days)USA Rush: 1x0.25g  
Catalog IDEN300-256911
Product classBuilding Block
Name1H-pyrazole-5-sulfonyl fluoride
ACD number
CAS number
Formula
MW150.1
CLogP0.972
Storage conditionsRT
Transport conditionsNormal
Global stock:> 10 g(5 business days)  
Catalog IDEN300-219830
Product classBuilding Block
Name1H-imidazole-2-sulfonyl fluoride
ACD numberMFCD29968596
CAS number1934502-26-7
Formula
MW150.1
CLogP0.497
Storage conditions+4
Transport conditionsNormal
Global stock:> 10 g(5 business days)  
USA rush delivery(2 business days)USA Rush: 1x1g  
Catalog IDEN300-31728
Product classBuilding Block
Namedifluoromethanesulfonyl chloride
ACD numberMFCD09971548
CAS number1512-30-7
Formula
MW150.5
CLogP-1.037
Storage conditions+4
Transport conditionsIce pack
Global stock:> 10 g(5 business days)  
USA rush delivery(2 business days)USA Rush: 1x0.25gUSA Rush: 1x0.5gUSA Rush: 1x1g  
Catalog IDEN300-170688
Product classBuilding Block
Name4H-1,2,4-triazole-3-sulfonyl fluoride
ACD numberMFCD20683378
CAS number78201-15-7
Formula
MW151.1
CLogP-0.55
Storage conditions+4
Transport conditionsNormal
Global stock:> 10 g(5 business days)  
USA rush delivery(2 business days)USA Rush: 1x1g  
Catalog IDEN300-727933
Product classBuilding Block
Name2-azidoethane-1-sulfonyl fluoride
ACD numberMFCD31445066
CAS number2137568-76-2
Formula
MW153.1
CLogP1.258
Storage conditions+4
Transport conditionsIce pack
Global stock:7.4 g(5 business days)  
Catalog IDEN300-182096
Product classBuilding Block
Namecyclobutanesulfonyl chloride
ACD numberMFCD09743768
CAS number338453-16-0
Formula
MW154.6
CLogP-0.42
Storage conditions-10
Transport conditionsIce pack
Global stock:> 10 g(5 business days)  
EU rush delivery(2 business days)EU Rush: 1x1g  
USA rush delivery(2 business days)USA Rush: 1x5g  
Catalog IDEN300-100820
Product classBuilding Block
Name1-methylcyclopropane-1-sulfonyl chloride
ACD numberMFCD19200529
CAS number923032-55-7
Formula
MW154.6
CLogP-0.46
Storage conditions+4
Transport conditionsIce pack
Global stock:> 10 g(5 business days)  
USA rush delivery(2 business days)USA Rush: 1x5g  
Catalog IDEN300-76109
Product classBuilding Block
Namecyclopropylmethanesulfonyl chloride
ACD numberMFCD10697744
CAS number114132-26-2
Formula
MW154.6
CLogP-0.36
Storage conditions-10
Transport conditionsIce pack
Global stock:> 10 g(5 business days)  
Catalog IDEN300-134034
Product classBuilding Block
NameN-cyclopropylsulfamoyl chloride
ACD numberMFCD14529124
CAS number391912-54-2
Formula
MW155.6
CLogP-0.285
Storage conditions+4
Transport conditionsNormal
Global stock:> 10 g(5 business days)  
EU rush delivery(2 business days)EU Rush: 1x0.1gEU Rush: 1x0.25gEU Rush: 1x0.5g  
Catalog IDEN300-207569
Product classBuilding Block
Nameazetidine-1-sulfonyl chloride
ACD numberMFCD19200214
CAS number639519-67-8
Formula
MW155.6
CLogP-0.158
Storage conditions-10
Transport conditionsIce pack
Global stock:> 10 g(5 business days)  
USA rush delivery(2 business days)USA Rush: 1x1g  
Catalog IDEN300-76495
Product classBuilding Block
Nameoxetane-3-sulfonyl chloride
ACD numberMFCD21645423
CAS number1393585-06-2
Formula
MW156.6
CLogP-0.998
Storage conditions-10
Transport conditionsIce pack
Global stock:> 10 g(5 business days)  
USA rush delivery(2 business days)USA Rush: 1x0.1g  
Catalog IDEN300-132862
Product classBuilding Block
Name1-[(chlorosulfonyl)amino]ethan-1-one
ACD numberMFCD19200128
CAS number50881-23-7
Formula
MW157.6
CLogP-1.298
Storage conditions-10
Transport conditionsIce pack
Global stock:> 10 g(5 business days)  
Catalog IDEN300-245261
Product classBuilding Block
Name2,2-difluorocyclopropane-1-sulfonyl fluoride
ACD number
CAS number1936720-48-7
Formula
MW160.1
CLogP0.926
Storage conditions+4
Transport conditionsNormal
Global stock:> 10 g(5 business days)  
Catalog IDEN300-734595
Product classBuilding Block
Namepyrazine-2-sulfonyl fluoride
ACD numberMFCD31559322
CAS number2090368-34-4
Formula
MW162.1
CLogP0.048
Storage conditions+4
Transport conditionsNormal
Global stock:> 10 g(5 business days)  
USA rush delivery(2 business days)USA Rush: 1x0.1gUSA Rush: 1x0.25gUSA Rush: 1x0.5g  
Catalog IDEN300-6732929
Product classBuilding Block
Name3-cyanocyclobutane-1-sulfonyl fluoride, Mixture of diastereomers
ACD numberMFCD31745935
CAS number2287343-20-6
Formula
MW163.2
CLogP0.088
Storage conditions-10
Transport conditionsIce pack
Global stock:4.8 g(5 business days)  
USA rush delivery(2 business days)USA Rush: 1x1g  
Catalog IDEN300-6731219
Product classBuilding Block
Name(1r,3r)-3-cyanocyclobutane-1-sulfonyl fluoride, trans
ACD number
CAS number2260918-03-2
Formula
MW163.2
CLogP0.088
Storage conditions-10
Transport conditionsIce pack
Global stock:> 10 g(5 business days)  
USA rush delivery(2 business days)USA Rush: 1x1g  
Catalog IDEN300-1693736
Product classBuilding Block
Name2-AMINOETHANE-1-SULFONYL FLUORIDE HYDROCHLORIDE
ACD numberMFCD20703078
CAS number1169199-27-2
Formula
MW163.6
CLogP-0.688
Storage conditions+4
Transport conditionsNormal
Global stock:> 10 g(5 business days)  
USA rush delivery(2 business days)USA Rush: 1x0.1gUSA Rush: 1x0.25g  
Catalog IDEN300-391793
Product classBuilding Block
Namecyclohex-3-ene-1-sulfonyl fluoride
ACD numberMFCD31381302
CAS number2126160-97-0
Formula
MW164.2
CLogP1.603
Storage conditions+4
Transport conditionsNormal
Global stock:> 10 g(5 business days)  
Catalog IDEN300-73503
Product classBuilding Block
Name2,2-difluoroethane-1-sulfonyl chloride
ACD numberMFCD16990719
CAS number1033906-60-3
Formula
MW164.6
CLogP-0.758
Storage conditions+4
Transport conditionsIce pack
Global stock:> 10 g(5 business days)  
EU rush delivery(2 business days)EU Rush: 2x0.1gEU Rush: 2x0.25gEU Rush: 2x0.5gEU Rush: 2x1g  
USA rush delivery(2 business days)USA Rush: 1x0.1g  
Catalog IDEN300-746798
Product classBuilding Block
Name2-methyl-2H-1,2,3,4-tetrazole-5-sulfonyl fluoride
ACD numberMFCD31559336
CAS number2137575-68-7
Formula
MW166.1
CLogP-0.254
Storage conditions+4
Transport conditionsNormal
Global stock:> 10 g(5 business days)  
USA rush delivery(2 business days)USA Rush: 1x0.1gUSA Rush: 1x0.25gUSA Rush: 1x0.5gUSA Rush: 1x1g  
Catalog IDEN300-7445026
Product classBuilding Block
Name(3-oxocyclobutyl)methanesulfonyl fluoride
ACD numberMFCD32199753
CAS number2377035-96-4
Formula
MW166.2
CLogP-0.901
Storage conditions+4
Transport conditionsIce pack
Global stock:> 10 g(5 business days)  
Catalog IDEN300-139041
Product classBuilding Block
Namefuran-2-sulfonyl chloride
ACD numberMFCD06658968
CAS number52665-48-2
Formula
MW166.6
CLogP-0.654
Storage conditions-10
Transport conditionsIce pack
Global stock:> 10 g(5 business days)  
USA rush delivery(2 business days)USA Rush: 2x1g  
Catalog IDEN300-82810
Product classBuilding Block
Namefuran-3-sulfonyl chloride
ACD numberMFCD08271875
CAS number52665-49-3
Formula
MW166.6
CLogP-0.654
Storage conditions+4
Transport conditionsIce pack
Global stock:> 10 g(5 business days)  
EU rush delivery(2 business days)EU Rush: 1x0.25gEU Rush: 1x0.5gEU Rush: 1x1g  
Catalog IDEN300-75269
Product classBuilding Block
Name1H-imidazole-4-sulfonyl chloride
ACD numberMFCD08687938
CAS number58767-51-4
Formula
MW166.6
CLogP-2.001
Storage conditions+4
Transport conditionsIce pack
Global stock:1.6 g(5 business days)  
Catalog IDEN300-218284
Product classBuilding Block
Name1H-imidazole-2-sulfonyl chloride
ACD numberMFCD18250099
CAS number281221-70-3
Formula
MW166.6
CLogP-2.001
Storage conditions-10
Transport conditionsIce pack
Global stock:> 10 g(5 business days)  
Catalog IDEN300-49990
Product classBuilding Block
Name1H-pyrazole-4-sulfonyl chloride
ACD numberMFCD09701481
CAS number438630-64-9
Formula
MW166.6
CLogP-1.731
Storage conditions-10
Transport conditionsIce pack
Global stock:> 10 g(5 business days)  
EU rush delivery(2 business days)EU Rush: 2x0.1gEU Rush: 2x0.25gEU Rush: 2x0.5gEU Rush: 2x1g  
USA rush delivery(2 business days)USA Rush: 1x0.1g  
Catalog IDEN300-224692
Product classBuilding Block
Name1,3-thiazole-2-sulfonyl fluoride
ACD numberMFCD09265516
CAS number934236-38-1
Formula
MW167.2
CLogP0.934
Storage conditions-10
Transport conditionsIce pack
Global stock:> 10 g(5 business days)  
USA rush delivery(2 business days)USA Rush: 1x5g  
Catalog IDEN300-70482
Product classBuilding Block
Name1,2-oxazole-4-sulfonyl chloride
ACD numberMFCD09803793
CAS number933740-94-4
Formula
MW167.6
CLogP-1.851
Storage conditions+4
Transport conditionsNormal
Global stock:> 10 g(5 business days)  
Catalog IDEN300-364777
Product classBuilding Block
Namemethyl (2E)-3-sulfoprop-2-enoate
ACD numberMFCD29047239
CAS number1909358-92-4
Formula
MW168.1
CLogP0.43
Storage conditions+4
Transport conditionsNormal
Global stock:> 10 g(5 business days)  
Catalog IDEN300-103781
Product classBuilding Block
Name(3-methyloxetan-3-yl)methanesulfonyl fluoride
ACD number
CAS number1935988-09-2
Formula
MW168.2
CLogP0.479
Storage conditions+4
Transport conditionsIce pack
Global stock:8.2 g(5 business days)  
Catalog IDEN300-321662
Product classBuilding Block
Name3-oxocyclobutane-1-sulfonyl chloride
ACD numberMFCD30641231
CAS number2090334-26-0
Formula
MW168.6
CLogP-1.046
Storage conditions-10
Transport conditionsIce pack
Global stock:6.6 g(5 business days)  
Catalog IDEN300-341823
Product classBuilding Block
Name1-methylcyclobutane-1-sulfonyl chloride
ACD numberMFCD31381256
CAS number2090155-98-7
Formula
MW168.6
CLogP0.099
Storage conditions+4
Transport conditionsNormal
Global stock:> 10 g(5 business days)  
Catalog IDEN300-117451
Product classBuilding Block
Namecyclobutylmethanesulfonyl chloride
ACD numberMFCD16036603
CAS number1220695-06-6
Formula
MW168.6
CLogP0.199
Storage conditions+4
Transport conditionsNormal
Global stock:> 10 g(5 business days)  
USA rush delivery(2 business days)USA Rush: 1x0.1gUSA Rush: 1x0.25g  
Catalog IDEN300-190372
Product classBuilding Block
Name(1-methylcyclopropyl)methanesulfonyl chloride
ACD numberMFCD10566319
CAS number1314903-62-2
Formula
MW168.6
CLogP0.159
Storage conditions-10
Transport conditionsIce pack
Global stock:> 10 g(5 business days)  
Catalog IDEN300-292199
Product classBuilding Block
Name3-methylcyclobutane-1-sulfonyl chloride, Mixture of diastereomers
ACD numberMFCD30336505
CAS number1691815-73-2
Formula
MW168.6
CLogP0.099
Storage conditions+4
Transport conditionsIce pack
Global stock:5.1 g(5 business days)  
USA rush delivery(2 business days)USA Rush: 1x1g  
Catalog IDEN300-6489868
Product classBuilding Block
Name2H-1,2,3-triazole-4-sulfonyl fluoride hydrofluoride
ACD numberMFCD31736478
CAS number2247103-77-9
Formula
MW171.1
CLogP-0.023
Storage conditions-10
Transport conditionsIce pack
Global stock:> 10 g(5 business days)  
USA rush delivery(2 business days)USA Rush: 1x0.1gUSA Rush: 1x0.25gUSA Rush: 1x0.5g  
Catalog IDEN300-30852
Product classBuilding Block
Namemethyl 2-(chlorosulfonyl)acetate
ACD numberMFCD00075558
CAS number56146-83-9
Formula
MW172.6
CLogP-1.203
Storage conditions+4
Transport conditionsIce pack
Global stock:> 10 g(5 business days)  
USA rush delivery(2 business days)USA Rush: 3x0.25gUSA Rush: 1x0.5gUSA Rush: 1x1g  
Catalog IDEN300-266428
Product classBuilding Block
Nameazetidine-3-sulfonyl fluoride hydrochloride
ACD numberMFCD29907176
CAS number1909305-42-5
Formula
MW175.6
CLogP-0.259
Storage conditions+4
Transport conditionsNormal
Global stock:> 10 g(5 business days)  
USA rush delivery(2 business days)USA Rush: 1x0.1gUSA Rush: 1x0.25gUSA Rush: 1x0.5gUSA Rush: 1x1gUSA Rush: 1x2.5g  
Catalog IDEN300-1478773
Product classBuilding Block
Name(E)-2-(furan-2-yl)ethene-1-sulfonyl fluoride
ACD numberMFCD31629519
CAS number1819971-32-8
Formula
MW176.2
CLogP1.965
Storage conditions+4
Transport conditionsNormal
Global stock:> 10 g(5 business days)  
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