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Diamine scaffolds


Diamine scaffolds are particularly useful templates for lead generation and lead optimization. Incorporation of such scaffolds can impart restricted confirmations with enhanced desirable physiochemical profile of the resulting products. Moreover these scaffolds have a proven track record in target class areas such as GCPRs. At the EnamineStore you will find readily available examples of diamine scaffold encompassing aliphatic ring systems including spiro, bridged and fused examples with appropriate ‘protection’ of one of the amine groups. Take a look below for representative examples.
StructureProduct infoAvailabilityQuantity / Price
Catalog IDEN300-101454
Product class Building Block
Nametert-butyl 3-(aminomethyl)azetidine-1-carboxylate
ACD numberMFCD01861762
CAS number325775-44-8
Formula
MW186.3
CLogP0.906
Storage conditions+4
Transport conditionsNormal
Purity: 95%Global stock:0.5 g(5 business days)  
Catalog IDEN300-343327
Product class Building Block
Nametert-butyl (1S,4S)-2,5-diazabicyclo[2.2.1]heptane-2-carboxylate
ACD numberMFCD01569250
CAS number113451-59-5
Formula
MW198.3
CLogP1.692
Storage conditions+4
Transport conditionsNormal
EU Rush delivery : (2 business days)
1x5 g
Catalog IDEN300-100907
Product class Building Block
Namerac-tert-butyl (3aR,6aS)-octahydropyrrolo[3,4-c]pyrrole-2-carboxylate, cis
ACD numberMFCD04116224
CAS number250275-15-1
Formula
MW212.3
CLogP1.507
Storage conditions+4
Transport conditionsNormal
USA Rush delivery(2 business days)
available in New Jersey stock : 1x1 g
Catalog IDEN300-154247
Product class Building Block
Nametert-butyl 4-aminoazepane-1-carboxylate
ACD numberMFCD07371372
CAS number196613-57-7
Formula
MW214.3
CLogP1.44
Storage conditionsRT
Transport conditionsNormal
USA Rush delivery(2 business days)
available in New Jersey stock : 2x1 g
Catalog IDEN300-90561
Product class Building Block
Nametert-butyl 3,9-diazabicyclo[3.3.1]nonane-9-carboxylate
ACD numberMFCD20441693
CAS number941295-31-4
Formula
MW226.3
CLogP2.438
Storage conditionsRT
Transport conditionsNormal
EU Rush delivery : (2 business days)
1x1 g
Catalog IDEN300-73843
Product class Building Block
Nametert-butyl 2,7-diazaspiro[3.5]nonane-2-carboxylate
ACD numberMFCD09834803
CAS number236406-55-6
Formula
MW226.3
CLogP1.322
Storage conditionsRT
Transport conditionsNormal
EU Rush delivery : (2 business days)
1x1 gUSA Rush delivery(2 business days)
available in New Jersey stock : 2x1 g
Catalog IDEN300-366826
Product class Building Block
Namerac-tert-butyl (3aR,6aS)-3a-methyl-octahydropyrrolo[3,4-c]pyrrole-2-carboxylate, trans
ACD numberMFCD30737568
CAS number2095396-65-7
Formula
MW226.3
CLogP2.026
Storage conditions+4
Transport conditionsNormal
Purity: 95%Global stock:0.2 g(5 business days)  
Catalog IDEN300-100953
Product class Building Block
Nametert-butyl 3,9-diazabicyclo[4.2.1]nonane-9-carboxylate
ACD numberMFCD18785763
CAS number1251015-63-0
Formula
MW226.3
CLogP1.88
Storage conditionsRT
Transport conditionsNormal
Purity: 95%Global stock:0.1 g(5 business days)  
Catalog IDEN300-212044
Product class Building Block
Nametert-butyl 2,7-diazaspiro[4.5]decane-2-carboxylate
ACD numberMFCD08234437
CAS number885268-42-8
Formula
MW240.3
CLogP2.253
Storage conditions+4
Transport conditionsNormal
USA Rush delivery(2 business days)
available in New Jersey stock : 1x1 g
Catalog IDEN300-247408
Product class Building Block
Nametert-butyl N-({6-azaspiro[3.4]octan-8-yl}methyl)carbamate
ACD numberMFCD29762660
CAS number1909336-06-6
Formula
MW240.3
CLogP1.624
Storage conditionsRT
Transport conditionsNormal
USA Rush delivery(2 business days)
available in New Jersey stock : 1x1 g
Catalog IDEN300-365073
Product class Building Block
Nametert-butyl 2,7-diazaspiro[3.5]nonane-7-carboxylate hydrochloride
ACD numberMFCD13185086
CAS number1023301-84-9
Formula
MW262.8
CLogP1.322
Storage conditions+4
Transport conditionsNormal
Purity: 95%Global stock:0.2 g(5 business days)  
Catalog IDEN300-373712
Product class Building Block
Nametert-butyl 2,6-diazaspiro[3.5]nonane-6-carboxylate hydrochloride
ACD numberMFCD22380770
CAS number1279844-25-5
Formula
MW262.8
CLogP2.066
Storage conditions+4
Transport conditionsNormal
Purity: 95%Global stock:0.2 g(5 business days)  
Catalog IDEN300-204916
Product class Building Block
Name2,2-dimethyl-1,4-diazepane
ACD numberMFCD19221013
CAS number105627-82-5
Formula
MW128.2
CLogP0.113
Storage conditionsRT
Transport conditionsNormal
USA Rush delivery(2 business days)
available in New Jersey stock : 1x5 g
Catalog IDEN300-366698
Product class Building Block
Name4H,5H,6H,7H-pyrazolo[1,5-a]pyrazin-2-amine
ACD numberMFCD28654772
CAS number1785544-01-5
Formula
MW138.2
CLogP-1.205
Storage conditionsRT
Transport conditionsNormal
 
Catalog IDEN300-136719
Product class Building Block
Name2,8-diazaspiro[4.5]decane
ACD numberMFCD16877059
CAS number176-67-0
Formula
MW140.2
CLogP-0.052
Storage conditions+4
Transport conditionsNormal
 
Catalog IDEN300-121071
Product class Building Block
Namedecahydroquinoxalin-6-ol
ACD numberMFCD23144011
CAS number1427378-50-4
Formula
MW156.2
CLogP-2.139
Storage conditionsRT
Transport conditionsNormal
Out of stock 20 working days
Catalog IDEN300-101297
Product class Building Block
NameN,N-dimethylpiperazine-2-carboxamide
ACD numberMFCD18268340
CAS number85817-21-6
Formula
MW157.2
CLogP-0.881
Storage conditionsRT
Transport conditionsNormal
USA Rush delivery(2 business days)
available in New Jersey stock : 1x1 g
Catalog IDEN300-120864
Product class Building Block
Name6-(trifluoromethyl)piperidin-3-amine, Mixture of diastereomers
ACD numberMFCD24279952
CAS number1141889-92-0
Formula
MW168.2
CLogP0.402
Storage conditions+4
Transport conditionsNormal
Out of stock 20 working days
Catalog IDEN300-55580
Product class Building Block
Namerac-tert-butyl N-[(1s,3s)-3-aminocyclobutyl]carbamate, cis
ACD numberMFCD11099896
CAS number1212395-34-0
Formula
MW186.3
CLogP1.337
Storage conditions+4
Transport conditionsNormal
EU Rush delivery : (2 business days)
1x1 gUSA Rush delivery(2 business days)
available in New Jersey stock : 1x1 g
Catalog IDEN300-117558
Product class Building Block
Nametert-butyl N-(2-aminocyclobutyl)carbamate
ACD numberMFCD20723359
CAS number1378864-01-7
Formula
MW186.3
CLogP0.871
Storage conditions+4
Transport conditionsNormal
USA Rush delivery(2 business days)
available in New Jersey stock : 1x1 g
Catalog IDEN300-27068
Product class Building Block
Nametert-butyl N-(3-aminocyclobutyl)carbamate, Mixture of diastereomers
ACD numberMFCD12755997
CAS number1090904-48-5
Formula
MW186.3
CLogP1.337
Storage conditions+4
Transport conditionsNormal
EU Rush delivery : (2 business days)
1x1 gUSA Rush delivery(2 business days)
available in New Jersey stock : 1x1 g
Catalog IDEN300-53089
Product class Building Block
Namerac-tert-butyl N-[(1r,3r)-3-aminocyclobutyl]carbamate
ACD numberMFCD09040641
CAS number871014-19-6
Formula
MW186.3
CLogP1.337
Storage conditions-10
Transport conditionsIce pack
EU Rush delivery : (2 business days)
1x0.25 g, 1x0.5 g, 1x1 g
Catalog IDEN300-140744
Product class Building Block
Nametert-butyl 3-amino-3-methylazetidine-1-carboxylate
ACD numberMFCD12408556
CAS number1158758-77-0
Formula
MW186.3
CLogP1.887
Storage conditions+4
Transport conditionsNormal
USA Rush delivery(2 business days)
available in New Jersey stock : 2x1 g
Catalog IDEN300-399915
Product class Building Block
Nametert-butyl (4R)-4-amino-1,2-oxazolidine-2-carboxylate
ACD numberMFCD31381394
CAS number2089610-73-9
Formula
MW188.2
CLogP1.229
Storage conditions+4
Transport conditionsIce pack
 
Catalog IDEN300-378067
Product class Building Block
Name1-[(3aR,6aS)-octahydropyrrolo[3,4-c]pyrrol-2-yl]ethan-1-one hydrochloride, cis
ACD numberMFCD30750058
CAS number2126144-11-2
Formula
MW190.7
CLogP-1.05
Storage conditionsRT
Transport conditionsNormal
USA Rush delivery(2 business days)
available in New Jersey stock : 1x5 g
Catalog IDEN300-82931
Product class Building Block
Nametert-butyl 5-amino-2-azabicyclo[2.1.1]hexane-2-carboxylate
ACD numberMFCD17977178
CAS number1258640-69-5
Formula
MW198.3
CLogP1.403
Storage conditions+4
Transport conditionsNormal
Out of stock 20 working days
Catalog IDEN300-268774
Product class Building Block
Namerac-tert-butyl N-[(1R,5S,6R)-3-azabicyclo[3.1.0]hexan-6-yl]carbamate, endo
ACD numberMFCD12198677
CAS number134575-17-0
Formula
MW198.3
CLogP1.185
Storage conditionsRT
Transport conditionsNormal
USA Rush delivery(2 business days)
available in New Jersey stock : 1x1 g
Catalog IDEN300-87141
Product class Building Block
Nametert-butyl (1R,5S,6R)-6-amino-3-azabicyclo[3.1.0]hexane-3-carboxylate
ACD numberMFCD09832898
CAS number273206-92-1
Formula
MW198.3
CLogP1.354
Storage conditions+4
Transport conditionsIce pack
USA Rush delivery(2 business days)
available in New Jersey stock : 1x1 g
Catalog IDEN300-26862
Product class Building Block
Nametert-butyl 6-amino-3-azabicyclo[3.1.0]hexane-3-carboxylate
ACD numberMFCD09040607
CAS number208837-83-6
Formula
MW198.3
CLogP1.354
Storage conditions+4
Transport conditionsNormal
Out of stock 20 working days
Catalog IDEN300-153078
Product class Building Block
Nametert-butyl (3-aminobicyclo[1.1.1]pentan-1-yl)carbamate
ACD numberMFCD27987307
CAS number1638767-25-5
Formula
MW198.3
CLogP1.758
Storage conditionsRT
Transport conditionsNormal
USA Rush delivery(2 business days)
available in New Jersey stock : 1x5 g
Catalog IDEN300-89740
Product class Building Block
Nametert-butyl 2,5-diazabicyclo[4.1.0]heptane-2-carboxylate
ACD numberMFCD17480504
CAS number1228675-18-0
Formula
MW198.3
CLogP1.78
Storage conditions-10
Transport conditionsIce pack
USA Rush delivery(2 business days)
available in New Jersey stock : 1x0.25 g, 1x0.5 g, 1x1 g
Catalog IDEN300-56094
Product class Building Block
Nametert-butyl N-{3-azabicyclo[3.1.0]hexan-6-yl}carbamate
ACD numberMFCD10698578
CAS number198211-38-0
Formula
MW198.3
CLogP1.185
Storage conditionsRT
Transport conditionsNormal
Out of stock 20 working days
Catalog IDEN300-179432
Product class Building Block
Nametert-butyl N-(4-methylpyrrolidin-3-yl)carbamate
ACD numberMFCD08461138
CAS number107610-92-4
Formula
MW200.3
CLogP1.47
Storage conditionsRT
Transport conditionsNormal
EU Rush delivery : (2 business days)
1x1 g
Catalog IDEN300-215193
Product class Building Block
Nametert-butyl N-[-2-methylpyrrolidin-3-yl]carbamate, cis
ACD numberMFCD31566986
CAS number1820571-09-2
Formula
MW200.3
CLogP1.47
Storage conditions+4
Transport conditionsNormal
Out of stock 20 working days
Catalog IDEN300-307325
Product class Building Block
Namerac-tert-butyl (3R,4S)-3-amino-4-hydroxypyrrolidine-1-carboxylate, cis
ACD numberMFCD14582421
CAS number138026-97-8
Formula
MW202.3
CLogP0.69
Storage conditions+4
Transport conditionsNormal
EU Rush delivery : (2 business days)
1x1 gUSA Rush delivery(2 business days)
available in New Jersey stock : 1x1 g
Catalog IDEN300-300052
Product class Building Block
Name6-benzyl-2,6-diazaspiro[3.4]octane
ACD numberMFCD08234736
CAS number135380-28-8
Formula
MW202.3
CLogP1.814
Storage conditions+4
Transport conditionsIce pack
Out of stock 20 working days
Catalog IDEN300-64022
Product class Building Block
Nametert-butyl N-[(1S,2S)-2-aminocyclopropyl]carbamate hydrochloride
ACD numberMFCD09878306
CAS number1332634-89-5
Formula
MW208.7
CLogP1.438
Storage conditions+4
Transport conditionsNormal
USA Rush delivery(2 business days)
available in New Jersey stock : 1x1 g
Catalog IDEN300-378608
Product class Building Block
Nametert-butyl 3-(1-aminocyclopropyl)azetidine-1-carboxylate
ACD numberMFCD22566184
CAS number1352012-69-1
Formula
MW212.3
CLogP0.636
Storage conditions+4
Transport conditionsNormal
 
Catalog IDEN300-67165
Product class Building Block
Nametert-butyl N-{2-azaspiro[3.3]heptan-6-yl}carbamate
ACD numberMFCD11858159
CAS number1118786-85-8
Formula
MW212.3
CLogP0.446
Storage conditionsRT
Transport conditionsNormal
Out of stock 20 working days
Catalog IDEN300-366886
Product class Building Block
Nametert-butyl N-({3-aminobicyclo[1.1.1]pentan-1-yl}methyl)carbamate
ACD numberMFCD27987306
CAS number1630906-49-8
Formula
MW212.3
CLogP0.379
Storage conditionsRT
Transport conditionsNormal
USA Rush delivery(2 business days)
available in New Jersey stock : 1x1 g
Catalog IDEN300-26877
Product class Building Block
Nametert-butyl (3aS,6aS)-octahydropyrrolo[3,4-b]pyrrole-5-carboxylate
ACD numberMFCD09040441
CAS number370882-55-6
Formula
MW212.3
CLogP1.693
Storage conditions+4
Transport conditionsNormal
Out of stock 20 working days
Catalog IDEN300-27794
Product class Building Block
Nametert-butyl 5-amino-2-azabicyclo[2.2.1]heptane-2-carboxylate, Mixture of diastereomers
ACD number
CAS number207405-62-7
Formula
MW212.3
CLogP1.16
Storage conditions+4
Transport conditionsNormal
EU Rush delivery : (2 business days)
1x1 gUSA Rush delivery(2 business days)
available in New Jersey stock : 1x1 g
Catalog IDEN300-56100
Product class Building Block
Nametert-butyl 3,7-diazabicyclo[4.2.0]octane-3-carboxylate
ACD numberMFCD08234914
CAS number885271-67-0
Formula
MW212.3
CLogP1.507
Storage conditions-10
Transport conditionsIce pack
Out of stock 20 working days
Catalog IDEN300-128723
Product class Building Block
Nametert-butyl 1-(aminomethyl)-2-azabicyclo[2.1.1]hexane-2-carboxylate
ACD numberMFCD17017103
CAS number1250997-62-6
Formula
MW212.3
CLogP1.499
Storage conditions+4
Transport conditionsNormal
USA Rush delivery(2 business days)
available in New Jersey stock : 1x0.1 g
Catalog IDEN300-224766
Product class Building Block
Nametert-butyl 3-(azetidin-3-yl)azetidine-1-carboxylate
ACD numberMFCD14581434
CAS number1251018-87-7
Formula
MW212.3
CLogP0.763
Storage conditions-10
Transport conditionsIce pack
Out of stock 20 working days
Catalog IDEN300-257954
Product class Building Block
Namerac-tert-butyl (1R,6S)-3,8-diazabicyclo[4.2.0]octane-3-carboxylate, cis
ACD numberMFCD17016497
CAS number370881-06-4
Formula
MW212.3
CLogP1.321
Storage conditionsRT
Transport conditionsNormal
USA Rush delivery(2 business days)
available in New Jersey stock : 1x0.25 g, 2x1 g
Catalog IDEN300-27793
Product class Building Block
Nametert-butyl 6-amino-2-azabicyclo[2.2.1]heptane-2-carboxylate, Mixture of diastereomers
ACD numberMFCD09040750
CAS number1005077-74-6
Formula
MW212.3
CLogP1.439
Storage conditions+4
Transport conditionsNormal
 
Catalog IDEN300-55271
Product class Building Block
Nametert-butyl 3,8-diazabicyclo[4.2.0]octane-3-carboxylate
ACD numberMFCD09056864
CAS number928754-14-7
Formula
MW212.3
CLogP1.321
Storage conditions-10
Transport conditionsIce pack
Out of stock 20 working days
Catalog IDEN300-1074346
Product class Building Block
Namerac-tert-butyl N-{[(1R,5S,6R)-3-azabicyclo[3.1.0]hexan-6-yl]methyl}carbamate
ACD numberMFCD14581078
CAS number134575-12-5
Formula
MW212.3
CLogP0.506
Storage conditions+4
Transport conditionsNormal
EU Rush delivery : (2 business days)
1x5 g
Catalog IDEN300-366466
Product class Building Block
Nametert-butyl 1-amino-3-azabicyclo[3.2.0]heptane-3-carboxylate
ACD numberMFCD14581339
CAS number1251009-41-2
Formula
MW212.3
CLogP1.962
Storage conditions+4
Transport conditionsNormal
Out of stock 20 working days
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