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Diamine scaffolds


Diamine scaffolds are particularly useful templates for lead generation and lead optimization. Incorporation of such scaffolds can impart restricted confirmations with enhanced desirable physiochemical profile of the resulting products. Moreover these scaffolds have a proven track record in target class areas such as GCPRs. At the EnamineStore you will find readily available examples of diamine scaffold encompassing aliphatic ring systems including spiro, bridged and fused examples with appropriate ‘protection’ of one of the amine groups. Take a look below for representative examples.

Search returned 220 hits.

StructureProduct infoAvailabilityQuantity / Price
Catalog IDEN300-204916
Product class Building Block
Name2,2-dimethyl-1,4-diazepane
ACD numberMFCD19221013
CAS number105627-82-5
Formula
MW128.2
CLogP0.113
Storage conditionsRT
Transport conditionsNormal
See details
Purity: 95%Global stock:> 10 g(5 business days)   USA Rush delivery(2 business days)
available in New Jersey stock : 1x5 g
Catalog IDEN300-366698
Product class Building Block
Name4H,5H,6H,7H-pyrazolo[1,5-a]pyrazin-2-amine
ACD numberMFCD28654772
CAS number1785544-01-5
Formula
MW138.2
CLogP-1.205
Storage conditionsRT
Transport conditionsNormal
See details
Now available as 94% pureGlobal stock:> 10 g(5 business days)  
Catalog IDEN300-136719
Product class Building Block
Name2,8-diazaspiro[4.5]decane
ACD numberMFCD16877059
CAS number176-67-0
Formula
MW140.2
CLogP-0.052
Storage conditions+4
Transport conditionsNormal
See details
Now available as 93% pureGlobal stock:> 10 g(5 business days)  
Catalog IDEN300-101297
Product class Building Block
NameN,N-dimethylpiperazine-2-carboxamide
ACD numberMFCD18268340
CAS number85817-21-6
Formula
MW157.2
CLogP-0.881
Storage conditionsRT
Transport conditionsNormal
See details
Purity: 95%Global stock:> 10 g(5 business days)   USA Rush delivery(2 business days)
available in New Jersey stock : 1x1 g
Catalog IDEN300-117558
Product class Building Block
Nametert-butyl N-(2-aminocyclobutyl)carbamate, Mixture of diastereomers
ACD numberMFCD20723359
CAS number1378864-01-7
Formula
MW186.3
CLogP0.871
Storage conditions+4
Transport conditionsNormal
See details
Purity: 95%Global stock:> 10 g(5 business days)   USA Rush delivery(2 business days)
available in New Jersey stock : 1x1 g
Catalog IDEN300-140744
Product class Building Block
Nametert-butyl 3-amino-3-methylazetidine-1-carboxylate
ACD numberMFCD12408556
CAS number1158758-77-0
Formula
MW186.3
CLogP1.887
Storage conditions+4
Transport conditionsIce pack
See details
Purity: 95%Global stock:> 10 g(5 business days)   USA Rush delivery(2 business days)
available in New Jersey stock : 1x1 g
Catalog IDEN300-53089
Product class Building Block
Namerac-tert-butyl N-[(1r,3r)-3-aminocyclobutyl]carbamate, trans
ACD numberMFCD09040641
CAS number871014-19-6
Formula
MW186.3
CLogP1.337
Storage conditions-10
Transport conditionsIce pack
See details
Purity: 95%Global stock:1.8 g(5 business days)   EU Rush delivery : (2 business days)
1x0.25 g, 1x0.5 g, 1x1 gUSA Rush delivery(2 business days)
available in New Jersey stock : 4x0.25 g, 4x0.5 g, 4x1 g
Catalog IDEN300-55580
Product class Building Block
Namerac-tert-butyl N-[(1s,3s)-3-aminocyclobutyl]carbamate, cis
ACD numberMFCD11099896
CAS number1212395-34-0
Formula
MW186.3
CLogP1.337
Storage conditions+4
Transport conditionsNormal
See details
Purity: 95%Global stock:7.5 g(5 business days)   EU Rush delivery : (2 business days)
1x1 gUSA Rush delivery(2 business days)
available in New Jersey stock : 2x1 g
Catalog IDEN300-101454
Product class Building Block
Nametert-butyl 3-(aminomethyl)azetidine-1-carboxylate
ACD numberMFCD01861762
CAS number325775-44-8
Formula
MW186.3
CLogP0.906
Storage conditions+4
Transport conditionsNormal
See details
Purity: 95%Global stock:> 10 g(5 business days)  
Catalog IDEN300-399915
Product class Building Block
Nametert-butyl (4R)-4-amino-1,2-oxazolidine-2-carboxylate
ACD numberMFCD31381394
CAS number2089610-73-9
Formula
MW188.2
CLogP1.229
Storage conditions+4
Transport conditionsIce pack
See details
Now available as 90% pureGlobal stock:> 10 g(5 business days)  
Catalog IDEN300-378067
Product class Building Block
Name1-[(3aR,6aS)-octahydropyrrolo[3,4-c]pyrrol-2-yl]ethan-1-one hydrochloride, cis
ACD numberMFCD30750058
CAS number2126144-11-2
Formula
MW190.7
CLogP-1.05
Storage conditionsRT
Transport conditionsNormal
See details
Purity: 95%Global stock:> 10 g(5 business days)   USA Rush delivery(2 business days)
available in New Jersey stock : 1x5 g
Catalog IDEN300-153078
Product class Building Block
Nametert-butyl (3-aminobicyclo[1.1.1]pentan-1-yl)carbamate
ACD numberMFCD27987307
CAS number1638767-25-5
Formula
MW198.3
CLogP1.758
Storage conditionsRT
Transport conditionsNormal
See details
Purity: 95%Global stock:> 10 g(5 business days)  
Catalog IDEN300-89740
Product class Building Block
Nametert-butyl 2,5-diazabicyclo[4.1.0]heptane-2-carboxylate
ACD numberMFCD17480504
CAS number1228675-18-0
Formula
MW198.3
CLogP1.78
Storage conditions-10
Transport conditionsIce pack
See details
Purity: 95%Global stock:> 10 g(5 business days)  
Catalog IDEN300-56094
Product class Building Block
Nametert-butyl N-{3-azabicyclo[3.1.0]hexan-6-yl}carbamate
ACD numberMFCD10698578
CAS number198211-38-0
Formula
MW198.3
CLogP1.185
Storage conditionsRT
Transport conditionsNormal
See details
Now available as 90% pureGlobal stock:0.3 g(5 business days)  
Catalog IDEN300-343327
Product class Building Block
Nametert-butyl (1S,4S)-2,5-diazabicyclo[2.2.1]heptane-2-carboxylate
ACD numberMFCD01569250
CAS number113451-59-5
Formula
MW198.3
CLogP1.692
Storage conditions+4
Transport conditionsNormal
See details
Purity: 95%Global stock:> 10 g(5 business days)   EU Rush delivery : (2 business days)
1x5 g
Catalog IDEN300-268774
Product class Building Block
Namerac-tert-butyl N-[(1R,5S,6R)-3-azabicyclo[3.1.0]hexan-6-yl]carbamate, endo
ACD numberMFCD12198677
CAS number134575-17-0
Formula
MW198.3
CLogP1.185
Storage conditionsRT
Transport conditionsNormal
See details
Purity: 95%Global stock:> 10 g(5 business days)   USA Rush delivery(2 business days)
available in New Jersey stock : 1x1 g
Catalog IDEN300-87141
Product class Building Block
Nametert-butyl (1R,5S,6R)-6-amino-3-azabicyclo[3.1.0]hexane-3-carboxylate
ACD numberMFCD09832898
CAS number273206-92-1
Formula
MW198.3
CLogP1.354
Storage conditions+4
Transport conditionsIce pack
See details
Purity: 95%Global stock:> 10 g(5 business days)   USA Rush delivery(2 business days)
available in New Jersey stock : 1x1 g
Catalog IDEN300-179432
Product class Building Block
Nametert-butyl N-(4-methylpyrrolidin-3-yl)carbamate
ACD numberMFCD08461138
CAS number107610-92-4
Formula
MW200.3
CLogP1.47
Storage conditionsRT
Transport conditionsNormal
See details
Purity: 95%Global stock:> 10 g(5 business days)   EU Rush delivery : (2 business days)
1x1 g
Catalog IDEN300-307325
Product class Building Block
Namerac-tert-butyl (3R,4S)-3-amino-4-hydroxypyrrolidine-1-carboxylate, cis
ACD numberMFCD14582421
CAS number138026-97-8
Formula
MW202.3
CLogP0.69
Storage conditions+4
Transport conditionsNormal
See details
Purity: 95%Global stock:> 10 g(5 business days)   EU Rush delivery : (2 business days)
1x1 g
Catalog IDEN300-300052
Product class Building Block
Name6-benzyl-2,6-diazaspiro[3.4]octane
ACD numberMFCD08234736
CAS number135380-28-8
Formula
MW202.3
CLogP1.814
Storage conditions+4
Transport conditionsIce pack
See details
Purity: 95%Global stock:0.5 g(5 business days)  
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