EnamineStore Blog

How It's Made

In this video overview we are going to show how Enamine's various departments are organized and how our chemists synthesize thousands of novel compounds each month to meet the ever growing demand of the drug discovery community for novel building blocks and screening compounds.

Enamine Empowers Drug Discovery Research With Innovative Chemistry

   by Enamine   
Enamine Empowers Drug Discovery Research With Innovative Chemistry

Founded in 1991, Enamine has grown into an industry leader with more than 500 full-time chemists, supplying building blocks and screening compounds to pharmaceutical and biotech companies as well as research organizations worldwide. 

In this video you can overview Enamine's main campus and its different departments and have a closer look at our operations. We are proud to have the world's largest pharma brands among our customers and therefore we put a great deal of effort into building a sustainable company with a reliable background. 

 

Enamine is active in synthesis of fluorinated building blocks

   by Enamine   
Enamine is active in synthesis of fluorinated building blocks

Since today around 25% of marketed drugs contain fluorine, the demand for fluorinated building blocks is growing. The introduction of fluorine into lead molecules during their optimization is a proved way to improve the pharmacokinetic and pharmacodynamic properties of drug candidates: increase metabolic stability, solubility, permeability, potency and allow conformational control due to the so-called gauche effect. 

At Enamine we perform a variety of fluorination reactions to synthesize fluorinated amines, carboxylic acids, pyrrolidines, morpholine analogues  and other fluorine-containing building blocks, especially popular among medicinal chemists.