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Metronidazole

Flagyl, Trichopol, Vagilen

Technical Data

Chemical name:Metronidazole
Formula:C6H9N3O3
Molecular weight:171.2
CAS number:443-48-1
SMILES:Cc1ncc(n1CCO)[N+]([O-])=O

Cat. No. BRC0170

BRC0170

Prices

1.0 mg $ 55.0
2.0 mg $ 56.0
5.0 mg $ 59.0
10.0 mg $ 78.0
20.0 mg $ 93.0
25.0 mg $ 100.0

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Biological activity

It belongs to next groups of Bioreference compounds:
Therapeutic areas:

Anti-infective   

Target:

Enzymes    Reductases    DNA    SUBDNA    RNA   

Description:

Metronidazole, a synthetic antibacterial and antiprotozoal agent of the nitroimidazole class, is used against protozoa. Metronidazole is a prodrug. Unionized metronidazole is selective for anaerobic bacteria due to their ability to intracellularly reduce metronidazole to its active form.

Targets:DNA, Oxygen-insensitive NADPH nitroreductase, Iron hydrogenase 1, Lanosterol 14-alpha demethylase
References:
1. BJOG. 2006 Jan; 113(1):65-74.; 
2. BJOG. 2005 Mar; 112 Suppl 1:67-73.; 
3. Ann Pharmacother. 2000 Feb; 34(2):255-7.; 
4. Ann Pharmacother. 2002 Jun; 36(6):971-4.;