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BW 755C

Technical Data

Chemical name:BW 755C
Formula:C10H10F3N3
Molecular weight:229.2
CAS number:66000-40-6
SMILES:NC1=NN(CC1)c1cccc(c1)C(F)(F)F |t:1|

Cat. No. BRC0329

BRC0329

Prices

1.0 mg $ 83.0
2.0 mg $ 85.0
5.0 mg $ 90.0
10.0 mg $ 117.0
20.0 mg $ 150.0
25.0 mg $ 170.0

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Biological activity

It belongs to next groups of Bioreference compounds:
Therapeutic areas:

Anti-Inflammatory   

Target:

Enzymes    Cyclooxygenase (COX)    Lipoxygenases   

Description:

BW-755C is a dual inhibitor of both cyclooxygenase and lipoxygenase pathways. It exerts an anti-inflammatory effect by inhibiting the formation of prostaglandins and leukotrienes. The drug also enhances pulmonary hypoxic vasoconstriction and has a protective effect after myocardial ischemia.

Targets:5-LO, COX-1, COX-2
References:
1. J Med Chem. 1990 May; 33(5):1491-6.; 
2. J Med Chem. 1991 May; 34(5):1560-70.;