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Abacavir sulfate

Ziagen, UNII-WR2TIP26VS, 1592U89

Technical Data

Chemical name:Abacavir sulfate
Formula:C28H38N12O6S
Molecular weight:670.8
CAS number:188062-50-2
SMILES:OS(O)(=O)=O.Nc1nc(NC2CC2)c2ncn([C@@H]3C[C@H](CO)C=C3)c2n1.Nc1nc(NC2CC2)c2ncn([C@@H]3C[C@H](CO)C=C3)c2n1 |c:22,46|

Cat. No. BRC0146

BRC0146

Prices

1.0 mg $ 87.0
2.0 mg $ 89.0
5.0 mg $ 95.0
10.0 mg $ 122.0
20.0 mg $ 158.0
25.0 mg $ 179.0

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Biological activity

It belongs to next groups of Bioreference compounds:
Target:

Enzymes    Reverse Transcriptase    RNA   

Description:

Abacavir is a carbocyclic synthetic nucleoside analogue and an antiviral agent. Intracellularly, abacavir is converted by cellular enzymes to the active metabolite carbovir triphosphate, an analogue of deoxyguanosine-5'-triphosphate (dGTP).

Targets:Reverse transcriptase/RNaseH
References:
1. J Acquir Immune Defic Syndr. 2007 May 1;45(1):1-3.; 
2. J. Med. Chem. 2002; 45(12), 2615-2623.; 
3. JAMA. 2004; 292(2), 191-201.;