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L-Pyroglutamic acid

NSC 143034; Oxoproline; Glutiminic acid; Pidolidone; Pidolic Acid;

Technical Data

Chemical name:L-Pyroglutamic acid
Formula:C5H7NO3
Molecular weight:129.1
CAS number:98-79-3
SMILES:OC(=O)[C@@H]1CCC(=O)N1

Cat. No. BRC1245

BRC1245

Prices

1.0 mg $ 86.0
2.0 mg $ 88.0
5.0 mg $ 94.0
10.0 mg $ 121.0
20.0 mg $ 146.0
25.0 mg $ 159.0

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Biological activity

It belongs to next groups of Bioreference compounds:
Target:

Enzyme-Linked Receptors    Cytokine receptors    Receptor Tyrosine Kinase    Ion Channels    Ligand-gated ion channels   

Description:

L-Pyroglutamic acid is an amino acid that is used in the synthesis of peptides. It is cyclooxygenase inhibitor.

Targets:Prostaglandin G/H synthase 1; Prostaglandin G/H synthase 2; cannabinoid receptor; thromboxane A2 receptor; Prostaglandin D2 receptor; Prostaglandin D2 receptor 2; Fatty-acid amide hydrolase 1; Ionotropic glutamate NMDA receptor; Glutamate 5-kinase; Pyroglutamyl-peptidase 1; CTP synthase; C-C motif chemokine 8; Vascular endothelial growth factor A;
References:
1. J. Mol. Biol. 2010; 404, 5, 890 - 901.; 2. Mol. Pharmacol. 1995; 48, 2, 219 - 229.; 3. Biochem. J. 2001; 356, 1, 223 - 232.;