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Balsalazide

Colazide, Giazo

Technical Data

Chemical name:Balsalazide
Formula:C17H15N3O6
Molecular weight:357.3
CAS number:80573-04-2
SMILES:OC(=O)CCNC(=O)c1ccc(cc1)N=Nc1ccc(O)c(c1)C(O)=O

Cat. No. BRC0842

BRC0842

Prices

1.0 mg $ 83.0
2.0 mg $ 86.0
5.0 mg $ 91.0
10.0 mg $ 119.0
20.0 mg $ 205.0
25.0 mg $ 225.0

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Biological activity

It belongs to next groups of Bioreference compounds:
Therapeutic areas:

Analgesics    Anti-Inflammatory   

Target:

Enzymes    Lipoxygenases    Nuclear Receptors (nuclear hormone receptors)    Peroxisome proliferator-activated receptor (PPAR)   

Description:

Balsalazide is a prodrug that produce mesalamine (5-aminosalicylic acid), an anti inflammatory drug.

Targets:Peroxisome proliferator-activated receptor gamma, Prostaglandin G/H synthase 2, Prostaglandin G/H synthase 1, Arachidonate 5-lipoxygenase
References:
1. J. Med. Chem. 2001; 44, 18, 3001 - 3013.; 
2. Science. 2008; 321(5886), 263-266.; 
3. J. Med. Chem. 2010; 53(7), 2719-2740.;