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Temozolomide

BRN 5547136, CCRG 81045, CCRIS 8996, MB 39831, Methazolastone, NSC 362856, Sch 52365, Temodal, Temodar, TMZ

Technical Data

Chemical name:Temozolomide
Formula:C6H6N6O2
Molecular weight:194.2
CAS number:85622-93-1
SMILES:Cn1nnc2c(ncn2c1=O)C(N)=O

Cat. No. BRC0164

BRC0164

Prices

1.0 mg $ 82.0
2.0 mg $ 84.0
5.0 mg $ 89.0
10.0 mg $ 116.0
20.0 mg $ 139.0
25.0 mg $ 151.0

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Biological activity

It belongs to next groups of Bioreference compounds:
Therapeutic areas:

Anti-cancer agents   

Target:

DNA    SUBDNA   

Description:

Temozolomide is an imidazotetrazine deritave and an antineoplastic agent. It is a prodrug that has little to no pharmacological activity until it is hydrolyzed in vivo to 5-(3-methyltriazen-1-yl)imidazole-4-carboxamide (MTIC).

Targets:DNA
References:
1. Cancer. 2010 Jun 15; 116(12):2868-77.; 
2. Neuro Oncol. 2009 Feb; 11(1):69-79.; 
3. Cancer Chemother Pharmacol. 2009 Sep; 64(4):647-55.;