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Hydrocortisone

NSC-10483

Technical Data

Chemical name:Hydrocortisone
Formula:C21H30O5
Molecular weight:362.5
CAS number:50-23-7
SMILES:C[C@]12C[C@H](O)[C@H]3[C@@H](CCC4=CC(=O)CC[C@]34C)[C@@H]1CC[C@]2(O)C(=O)CO |t:9|

Cat. No. BRC0836

BRC0836

Prices

1.0 mg $ 86.0
2.0 mg $ 88.0
5.0 mg $ 94.0
10.0 mg $ 121.0
20.0 mg $ 146.0
25.0 mg $ 159.0

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Biological activity

It belongs to next groups of Bioreference compounds:
Therapeutic areas:

Anti-Inflammatory    Steroids   

Target:

Enzymes    Dehydrogenase    Nuclear Receptors (nuclear hormone receptors)    Glucocorticoid receptor    Multidrug Transporter Inhibitors    P-glycoprotein/ABCB1   

Description:

Hydrocortisone is steroid hormone of the adrenal cortex with anti-inflammatory properties.

Targets:Glucocorticoid receptor, Annexin A1, Corticosteroid 11-beta-dehydrogenase isozyme 2, 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1
References:
1. Mol Endocrinol. 2004; 18, 9, 2151 - 2165.; 
2. Biochem. Pharmacol. 2000; 59, 2, 167 - 175.; 
3. Steroids. 1996; 61, 3, 133 - 137.;