EnamineStore

Welcome, Guest
Tutorials

Return to Search menu

Simvastatin

C10AA01, MK 733, Eucor, Kolestevan, L 644128-000U

Technical Data

Chemical name:Simvastatin
Formula:C25H38O5
Molecular weight:418.6
CAS number:79902-63-9
SMILES:CCC(C)(C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CC[C@@H]3C[C@@H](O)CC(=O)O3)[C@@H]12 |c:14,t:12|

Cat. No. BRC0768

BRC0768

Prices

1.0 mg $ 82.0
2.0 mg $ 84.0
5.0 mg $ 89.0
10.0 mg $ 116.0
20.0 mg $ 139.0
25.0 mg $ 151.0

Make inquiry

Biological activity

It belongs to next groups of Bioreference compounds:
Target:

Enzymes    Reductases    Enzyme-Linked Receptors    Integrin    Multidrug Transporter Inhibitors    P-glycoprotein/ABCB1   

Description:

Simvastatin is the methylated form of lovastatin, an oral antilipemic agent which inhibits HMG-CoA reductase.

Targets:3-hydroxy-3-methylglutaryl-coenzyme A reductase, Integrin beta-2, Integrin alpha-L
References:
1. BMC Med. 2007 Jul 19; 5:20.; 
2. Bioorg. Med. Chem. Lett. 2005; 15, 4, 989.; 
3. ChemMedChem. 2012; 7, 11, 1882.;