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Podophyllotoxin

Condylox, Podofilox, PPT

Technical Data

Chemical name:Podophyllotoxin
Formula:C22H22O8
Molecular weight:414.4
CAS number:518-28-5
SMILES:COc1cc(cc(OC)c1OC)[C@H]1[C@@H]2[C@H](COC2=O)[C@@H](O)c2cc3OCOc3cc12

Cat. No. BRC0315

BRC0315

Prices

1.0 mg $ 82.0
2.0 mg $ 84.0
5.0 mg $ 89.0
10.0 mg $ 116.0
20.0 mg $ 139.0
25.0 mg $ 151.0

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Biological activity

It belongs to next groups of Bioreference compounds:
Therapeutic areas:

Anti-cancer agents    Antiviral   

Target:

DNA    SUBDNA   

Description:

Podofilox, also called podophyllotoxin, is a purer and more stable form of podophyllin in which only the biologically active portion of the compound is present.

Targets:DNA topoisomerase 2-alpha, Tubulin alpha-4A chain, Tubulin beta chain,
References:
1. Cancer Res. 1983; 43, 505.; 
2. Chem. Pharmacol. Bull. (Tokyo). 1992; 40, 2720.; 
3. Pharmacol. Therap. 1993; 59, 163.; 
4. Arch. Pharmacol. 1994; 327, 175.; 
5. Cosmet. Laser Ther. 2003; 5, 35.; 
6. Dermatol. Online J. 2006; 12, 5.;