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Chloroxine

Endiaron; NSC 3904; Quesyl; CHQ;

Technical Data

Chemical name:Chloroxine
Formula:C9H5Cl2NO
Molecular weight:214.0
CAS number:773-76-2
SMILES:OC1=C2N=CC=CC2=C(Cl)C=C1Cl

Cat. No. BRC0580

BRC0580

Prices

1.0 mg $ 61.0
2.0 mg $ 62.0
5.0 mg $ 65.0
10.0 mg $ 86.0
20.0 mg $ 94.0
25.0 mg $ 102.0

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Biological activity

It belongs to next groups of Bioreference compounds:
Therapeutic areas:

Anti-infective    Antifungals    Antibacterial   

Target:

Kinases    Vascular endothelial growth factor (VEGF)    Enzymes    Kinases    Lipoxygenases    Integrases    Enzyme-Linked Receptors    Receptor Tyrosine Kinase   

Description:

Chloroxine is a synthetic antibacterial compound. It inhibits the growth of gram-positive as well as some gram-negative organisms.

Targets:arachidonate 15-lipoxygenase; Integrase - Pc4 And Sfrs1 Interacting Protein 1 Complex; Botulinum neurotoxin type A; Vascular endothelial growth factor receptor 2; Tyrosine-protein kinase JAK2; Glycogen synthase kinase-3 beta; Receptor-type tyrosine-protein kinase FLT3; Ribosomal protein S6 kinase beta-1;
References:
1. ChemMedChem. 2015; 10, 7,  1157 - 1162.; 2. J Med Chem. 2011; 54, 15, 5485 - 5497.; 3. PLoS ONE. 2015; 10, 7.;