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ETP-45835

Technical Data

Chemical name:ETP-45835
Formula:C13H18Cl2N4
Molecular weight:301.2
CAS number:794510-70-6
SMILES:Cl.Cl.C1CC(CCN1)c1cc([nH]n1)-c1ccncc1

Cat. No. BRC0340

BRC0340

Prices

1.0 mg $ 144.0
2.0 mg $ 150.0
5.0 mg $ 162.0
10.0 mg $ 180.0
20.0 mg $ 350.0
25.0 mg $ 420.0

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Biological activity

It belongs to next groups of Bioreference compounds:
Target:

Kinases    Mitogen-activated protein kinase (MAPK)    Kinases   

Description:

Mnk2 and Mnk1 inhibitor (IC50 values are 575 and 646 nM respectively). Exhibits selectivity against a panel of 24 protein kinases, including those upstream of Mnk1/2.

Targets:MNK1, MNK2
References:
1. J. Med. Chem. 2010; 53, 6618.; 
2. SAR and QSAR in Environmental Research. 2015; 26(5), 343-361.;