EnamineStore

Welcome, Guest
Tutorials

Return to Search menu

Hydrochlorothiazide

HCTZ, NSC 53477, SU 5879

Technical Data

Chemical name:Hydrochlorothiazide
Formula:C7H8ClN3O4S2
Molecular weight:297.7
CAS number:58-93-5
SMILES:NS(=O)(=O)c1cc2c(NCNS2(=O)=O)cc1Cl

Cat. No. BRC0370

BRC0370

Prices

1.0 mg $ 82.0
2.0 mg $ 84.0
5.0 mg $ 89.0
10.0 mg $ 116.0
20.0 mg $ 139.0
25.0 mg $ 151.0

Make inquiry

Biological activity

It belongs to next groups of Bioreference compounds:
Therapeutic areas:

Antihypertensive    Cardiovascular   

Target:

Ion Channels    Potassium channel    Calcium channel    Solute carrier family (SLC)   

Description:

A thiazide diuretic often considered the prototypical member of this class. It reduces the reabsorption of electrolytes from the renal tubules. Hydrochlorothiazide results in increased excretion of water and electrolytes, including sodium, potassium, chloride, and magnesium.

Targets:Solute carrier family 12 member 3, Carbonic anhydrase 1, Carbonic anhydrase 2, Carbonic anhydrase 4, Carbonic anhydrase 9, Carbonic anhydrase 12, Calcium-activated potassium channel subunit alpha-1
References:
1. J. Pharmacol. Exp. Ther. 1961; 134, 273.; 
2. Anal. Profiles Drug Subs. 1981; 10, 405.;