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Nalidixic Acid

NSC-82174

Technical Data

Chemical name:Nalidixic Acid
Formula:C12H12N2O3
Molecular weight:232.2
CAS number:389-08-2
SMILES:CCn1cc(C(O)=O)c(=O)c2ccc(C)nc12

Cat. No. BRC0408

BRC0408

Prices

1.0 mg $ 82.0
2.0 mg $ 84.0
5.0 mg $ 89.0
10.0 mg $ 116.0
20.0 mg $ 139.0
25.0 mg $ 151.0

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Biological activity

It belongs to next groups of Bioreference compounds:
Therapeutic areas:

Anti-cancer agents    Anti-infective    Antibacterial   

Target:

Enzymes    Topoisomerase    DNA    SUBDNA   

Description:

Nalidixic acid is a quinolone antibacterial agent for oral administration. Nalidixic acid has marked antibacterial activity against gram-negative bacteria including Enterobacter species, Escherichia coli, Morganella Morganii; Proteus Mirabilis, Proteus vulgaris, and Providencia rettgeri. Pseudomonas species are generally resistant to the drug.

Targets:DNA
References:
1. Br Med J. 1977; 2 (6101): 1518.; 
2. Proc R Soc Med. 1973; 66 (8): 747.; 
3. Br Med J. 1972; 4 (5838): 493.; 
4. Cjem. 2006; 8 (2): 78.;