EnamineStore

Welcome, Guest
Tutorials

Return to Search menu

Methoxyflurane

DA-759; NSC-110432;

Technical Data

Chemical name:Methoxyflurane
Formula:C3H4Cl2F2O
Molecular weight:165.0
CAS number:76-38-0
SMILES:COC(F)(F)C(Cl)Cl

Cat. No. BRC0692

BRC0692

Prices

1.0 mg $ 86.0
2.0 mg $ 88.0
5.0 mg $ 94.0
10.0 mg $ 121.0
20.0 mg $ 146.0
25.0 mg $ 159.0

Make inquiry

Biological activity

It belongs to next groups of Bioreference compounds:
Therapeutic areas:

Analgesics    CNS Agents   

Target:

G-Protein-Coupled Receptors (GPCRs)    Glutamate receptor    GABA receptors    Enzymes    Reductases    Ion Channels    Potassium channel    Ligand-gated ion channels    Transporters    Ion Pumps   

Description:

Methoxyflurane is an anesthetic used for induction and maintenance of general anesthesia. It induces muscle relaxation and reduces pains sensitivity by altering tissue excitability.

Targets:Gamma-aminobutyric acid receptor subunit alpha-1; Glutamate receptor 1; Glycine receptor subunit alpha-1; Calcium-transporting ATPase type 2C member 1; Potassium voltage-gated channel subfamily A member 1; ATP synthase subunit delta, mitochondrial; NADH-ubiquinone oxidoreductase chain 1; GABA-A receptor (anion channel);
References:
1. Br J Pharmacol. 2000; 129(4), 731-43.; 2. J Biol Chem. 1995; 270(47), 28239-45.; 3. Nat Rev Drug Discov. 2006; 5(12):993-6.;