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Tioxolone

Camyna; OL 110; Stepin; Acnosan;

Technical Data

Chemical name:Tioxolone
Formula:C7H4O3S
Molecular weight:168.2
CAS number:4991-65-5
SMILES:OC1=CC=C2SC(=O)OC2=C1

Cat. No. BRC1057

BRC1057

Prices

1.0 mg $ 82.0
2.0 mg $ 84.0
5.0 mg $ 89.0
10.0 mg $ 116.0
20.0 mg $ 139.0
25.0 mg $ 151.0

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Biological activity

It belongs to next groups of Bioreference compounds:
Therapeutic areas:

Anti-infective    Antibacterial   

Target:

Enzymes    Carbonic Anhydrase   

Description:

Tioxolone is a metalloenzyme carbonic anhydrase I inhibitor (Ki of 91 nM). It possess cytostatic, antipsoriatic, antibacterial and anti-mycotic properties. Tioxolone is also added to some cosmetics.

Targets:Carbonic anhydrase 1; Carbonic anhydrase 2; Carbonic anhydrase 6; Carbonic anhydrase 7; Carbonic anhydrase-related protein 10; Carbonic anhydrase 4; Carbonic anhydrase 5; Carbonic anhydrase 14; Carbonic anhydrase 12; Carbonic anhydrase 15; Carbonic anhydrase 13; Carbonic anhydrase-related protein 11; Carbonic anhydrase 3; Carbonic anhydrase-related protein 8; Carbonic anhydrase 9;
References:
1. Bioorg Med Chem Lett. 2008; 18, 14, 3938 - 3941.; 2. J Enzyme Inhib Med Chem. 2012; 27, 4, 467 - 475.; 3. Bioorg Med Chem Lett. 2016; 26, 4, 1200 - 1204.;