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α-Liponic acid

NSC 628502; NSC 90788; Octolipen; (±)-Lipoic acid; Thioctic acid;

Technical Data

Chemical name:α-Liponic acid
Formula:C8H14O2S2
Molecular weight:206.3
CAS number:1077-28-7
SMILES:OC(=O)CCCCC1CCSS1

Cat. No. BRC1313

BRC1313

Prices

1.0 mg $ 61.0
2.0 mg $ 62.0
5.0 mg $ 65.0
10.0 mg $ 86.0
20.0 mg $ 94.0
25.0 mg $ 102.0

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Biological activity

It belongs to next groups of Bioreference compounds:
Therapeutic areas:

Anti-cancer agents   

Target:

G-Protein-Coupled Receptors (GPCRs)    Adenosine receptor    Enzymes    Acetylcholinesterase    Dehydrogenase    Phosphatases   

Description:

α-Liponic acid is a metabolic antioxidant that regulates NFκB signal transduction and can protect against oxidative injury.

Targets:Nuclear receptor subfamily 1 group I member 2; Amyloid beta A4 protein; Prostaglandin G/H synthase 1; Major prion protein; 1-lipoxygenase; Acetylcholinesterase; Adenosine triphosphatase; Glutathione S-transferase; Lactate dehydrogenase;
References:
1. Free Radic. Biol. Med. 1996; 1997, 22(1/2), 359-378.; 2. Drug Metab. Dispos. 2011; 39, 1, 151 - 159.; 3. Curr. Med. Chem. 2010; 17, 27, 2990 - 3006.;