EnamineStore

Welcome, Guest
Tutorials

Return to Search menu

Antipyrine

Technical Data

Chemical name:Antipyrine
Formula:C11H12N2O
Molecular weight:188.2
CAS number:60-80-0
SMILES:CN1N(C(=O)C=C1C)C1=CC=CC=C1

Cat. No. BRC0978

BRC0978

Prices

1.0 mg $ 55.0
2.0 mg $ 56.0
5.0 mg $ 59.0
10.0 mg $ 78.0
20.0 mg $ 93.0
25.0 mg $ 100.0

Make inquiry

Biological activity

It belongs to next groups of Bioreference compounds:
Therapeutic areas:

Analgesics    Anti-Inflammatory    CNS Agents   

Target:

Description:

Antipyrine is an analgesic and antipyretic. It inhibits isoforms of cyclooxygenase, COX-1, COX-2, and COX-3 enzymes involved in prostaglandin (PG) synthesis. Antipyrine is often used in testing the effects of other drugs or diseases on drug-metabolizing enzymes in the liver.

Targets:Prostaglandin G/H synthase 2; Prostaglandin G/H synthase 1;
References:
1. Curr Drug Metab. 2010; 11, 2, 153 - 161.; 2. Drug Metab Dispos. 2000; 28, 12, 1518 - 1523.; 3. Clin Pharmacol Ther. 2007; 82, 3, 265 - 274.;