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Theobromine

NSC-5039; SC-15090; Diurobromine;

Technical Data

Chemical name:Theobromine
Formula:C7H8N4O2
Molecular weight:180.2
CAS number:83-67-0
SMILES:CN1C=NC2=C1C(=O)NC(=O)N2C

Cat. No. BRC0968

BRC0968

Prices

1.0 mg $ 55.0
2.0 mg $ 56.0
5.0 mg $ 59.0
10.0 mg $ 78.0
20.0 mg $ 93.0
25.0 mg $ 100.0

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Biological activity

It belongs to next groups of Bioreference compounds:
Therapeutic areas:

Cardiovascular    Diuretics   

Target:

G-Protein-Coupled Receptors (GPCRs)    Adenosine receptor    Enzymes    Phosphodiesterases (PDE)    Transporters    Ion Pumps   

Description:

Theobromine is a purine alkaloid that is an adenosine receptor antagonist, weak PDE (phosphodiesterase) inhibitor. It is a diuretic and smooth-muscle relaxant.

Targets:Adenosine receptor A1; Adenosine receptor A2a; cAMP-specific 3,5-cyclic phosphodiesterase 4B;
References:
1. Curr Top Med Chem. 2012; 12, 13, 1392 - 1407.; 2. J Med Chem. 1990; 33, 10, 2818 - 2821.; 3. Bioorg Med Chem Lett. 2010; 20, 1, 141 - 144.;