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2-Oxoglutaric acid

NSC 17391; 2-Ketoglutaric acid;

Technical Data

Chemical name:2-Oxoglutaric acid
Formula:C5H6O5
Molecular weight:146.1
CAS number:328-50-7
SMILES:OC(=O)CCC(=O)C(O)=O

Cat. No. BRC1316

BRC1316

Prices

1.0 mg $ 57.0
2.0 mg $ 58.0
5.0 mg $ 62.0
10.0 mg $ 82.0
20.0 mg $ 98.0
25.0 mg $ 105.0

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Biological activity

It belongs to next groups of Bioreference compounds:
Target:

Kinases    Mammalian target of rapamycin (mTOR)    Enzymes    Kinases    Dehydrogenase   

Description:

2-Oxoglutaric acid is an intermediate in the Krebs cycle catalyzed by glutamate dehydrogenase enzyme on glutamate.

Targets:Lysine-specific demethylase 2A; Serine/threonine-protein kinase mTOR; Pyruvate kinase (gene pyk); Alanine aminotransferase; Aspartate aminotransferase; Lactate dehydrogenase; Superoxide dismutase;
References:
1. Nature. 2014; 510, 7505, 397 - 401.; 2. Science. 2009; 324(5929), 930-935.; 3. Cancer Cell. 2010; 18(6), 553-567.;