5-FU, Carzonal, Efudix, Efurix, Ftoruracil, NSC 19893
Cat. No. BRC0031
|It belongs to next groups of Bioreference compounds:|
Fluorouracil is an antineoplastic anti-metabolite. Anti-metabolites masquerade as purine or pyrimidine - which become the building blocks of DNA. They prevent these substances from becoming incorporated into DNA during the "S" phase (of the cell cycle), stopping normal development and division.
|Targets:||Thymidylate synthase, DNA, RNA|
1. Nat Rev Cancer. 2003 May; 3(5):330-8.; 2. J. Curr Cancer Drug Targets. 2004 Mar; 4(2):191-204.;