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Methimazole

NSC 38608; UNII-554Z48XN5E; Danantizol; Metizol; Thiamazol;

Technical Data

Chemical name:Methimazole
Formula:C4H6N2S
Molecular weight:114.2
CAS number:60-56-0
SMILES:CN1C=CN=C1S

Cat. No. BRC0991

BRC0991

Prices

1.0 mg $ 57.0
2.0 mg $ 58.0
5.0 mg $ 62.0
10.0 mg $ 82.0
20.0 mg $ 98.0
25.0 mg $ 105.0

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Biological activity

It belongs to next groups of Bioreference compounds:
Target:

Enzymes    Peroxidases   

Description:

Methimazole is thioureylene antithyroid agent that inhibits the formation of thyroid hormones by interfering with the incorporation of iodine into tyrosyl residues of thyroglobulin.

Targets:Thyroid peroxidase;
References:
1. Bioorg Med Chem. 2014; 22, 9, 2809 - 2815.; 2. Proc Natl Acad Sci U S A. 2012; 109, 2, 378 - 383.; 3. J Med Chem. 2006; 49, 23, 6660 - 6671.;