NSC 79560; NSC 9791; Animal galactose factor;
|Chemical name:||Orotic Acid|
Cat. No. BRC1013
|It belongs to next groups of Bioreference compounds:|
Orotic acid is an intermediate in de novo pyrimidine biosynthesis that may be used to study the specificity and kinetics of orotate phosphoribosyltransferase (OPRT) which catalyzes the reversible phosphoribosyl transfer from 5′-phospho-α-d-ribose 1′-diphosphate (PRPP) to orotic acid, forming pyrophosphate and orotidine 5′-monophosphate (OMP). It may be used to study dependent cell signaling pathways and transcription regulation mechanisms that induce hepatic lipogenesis.
|Targets:||Orotate phosphoribosyltransferase; Dihydroorotate dehydrogenase (quinone), mitochondrial; Dihydroorotate dehydrogenase (quinone); Dihydroorotase; Dihydroorotate dehydrogenase A (fumarate);|
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