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Amantadine hydrochloride

Aminoadamantane, Viregyt, Virosol, PK-Merz, Symadine, Symmetrel

Technical Data

Chemical name:Amantadine hydrochloride
Formula:C10H18ClN
Molecular weight:187.7
CAS number:665-66-7
SMILES:Cl.NC12CC3CC(CC(C3)C1)C2

Cat. No. BRC0260

BRC0260

Prices

1.0 mg $ 55.0
2.0 mg $ 56.0
5.0 mg $ 59.0
10.0 mg $ 78.0
20.0 mg $ 93.0
25.0 mg $ 100.0

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Biological activity

It belongs to next groups of Bioreference compounds:
Therapeutic areas:

Analgesics    Anti-infective    CNS Agents    Antiparkinson   

Target:

G-Protein-Coupled Receptors (GPCRs)    Dopamine receptor    Glutamate receptor    Ion Channels    Ligand-gated ion channels    Transporters    Ion Pumps   

Description:

Amantadine is an antiviral drug which also acts as an antiparkinson agent, for which it is usually combined with L-DOPA when L-DOPA responses decline (probably due to tolerance).

Targets:Matrix protein 2, Glutamate receptor ionotropic, NMDA 3A, D(2) dopamine receptor
References:
1. Journal of Infectious Diseases. 2007; 196 (2): 249–257.; 
2. Br Med J. 1971; 2 (5762): 627–8.; 
3. Proc. Natl. Acad. Sci. U.S.A. 2008; 105 (31): 10967–72.;