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LY294002

NSC 697286, SF 1101, LY 294002

Technical Data

Chemical name:LY294002
Formula:C19H17NO3
Molecular weight:307.3
CAS number:154447-36-6
SMILES:O=c1cc(oc2c(cccc12)-c1ccccc1)N1CCOCC1

Cat. No. BRC0433

BRC0433

Prices

1.0 mg $ 112.0
2.0 mg $ 117.0
5.0 mg $ 126.0

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Biological activity

It belongs to next groups of Bioreference compounds:
Therapeutic areas:

Anti-cancer agents   

Target:

Kinases    Phosphatidylinositol 3-kinase (PDK)    Kinases    Autophagy   

Description:

LY294002 is a potent inhibitor of numerous proteins, and a strong inhibitor of phosphoinositide 3-kinases (PI3Ks).

Targets:Serine/threonine-protein kinase pim-1, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
References:
1. Biochem.J. 2007; 408, 297; 
2. Cell Biol.Int. 2007; 31, 330.; 
3. Eur.J.Biochem. 1997; 243, 240.; 
4. J.Biol.Chem. 1994; 269, 5241.;