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Progesterone

BP 14, NSC-64377, NSC-9704, U 3672

Technical Data

Chemical name:Progesterone
Formula:C21H30O2
Molecular weight:314.5
CAS number:57-83-0
SMILES:CC(=O)[C@H]1CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3CC[C@]12C |t:10|

Cat. No. BRC0866

BRC0866

Prices

1.0 mg $ 86.0
2.0 mg $ 88.0
5.0 mg $ 94.0
10.0 mg $ 121.0
20.0 mg $ 146.0
25.0 mg $ 159.0

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Biological activity

It belongs to next groups of Bioreference compounds:
Therapeutic areas:

Steroids   

Target:

Nuclear Receptors (nuclear hormone receptors)    Progesterone receptor    Glucocorticoid receptor    Androgen receptor   

Description:

Progesterone is steroid hormone produced by the corpus luteum. It is endogenous progesterone receptor (PR) agonist (EC50 = 0.5 nM).

Targets:Progesterone receptor, Estrogen receptor alpha, Mineralocorticoid receptor, Steroid 17-alpha-hydroxylase/17,20 lyase, Kappa-type opioid receptor, Nuclear receptor subfamily 1 group I member 2, Alpha-1-acid glycoprotein 1, Glucocorticoid receptor, Androgen receptor, Sex hormone-binding globulin
References:
1. Biochem. Pharmacol. 2009; 77, 2, 204 - 215.; 
2. Eur. J. Pharmacol. 1996; 303, 3, 227 - 234.; 
3. Steroids. 2002; 67, 5, 323 - 332.;