EnamineStore

Welcome, Guest
Tutorials

Return to Search menu

SB-347804

Technical Data

Chemical name:SB-347804
Formula:C16H13FN2OS
Molecular weight:300.4
CAS number:325979-58-6
SMILES:Fc1ccc(cc1)C(=O)Nc1sc2CCCCc2c1C#N

Cat. No. BRC0556

BRC0556

Prices

1.0 mg $ 82.0
2.0 mg $ 84.0
5.0 mg $ 89.0
10.0 mg $ 116.0
20.0 mg $ 139.0
25.0 mg $ 151.0

Make inquiry

Biological activity

It belongs to next groups of Bioreference compounds:
Target:

Kinases    c-Jun N-terminal kinases (JNKs)    Mitogen-activated protein kinase (MAPK)    Kinases    Enzyme-Linked Receptors    Receptor protein serine/threonine kinases   

Description:

SB-347804 is a potent and selective inhibitor of JNK3 kinase (IC50 = 3.16 μM).

Targets:Mitogen-activated protein kinase 1, c-Jun N-terminal kinase 2, c-Jun N-terminal kinase 3
References:
1. Bioorg. Med. Chem Letters. 2007; 17(5), 1296-1301.; 
2. Mini Rev Med Chem. 2008; 8, 8, 755 - 766.;